FET 준비 프로토콜이 자내막 연동운동에 미치는 영향: 전향적 코호트 연구 (EPFE)

Time point for measurement

Endometrial peristalsis will be assessed at three specific time points:

• On the second day to the fourth day of the menstrual cycle in the FET cycles.
• The day of hCG trigger, (before progesterone exposure)
• On the day of embryo transfer, immediately prior to the procedure

Hormone measurements

Serum levels of estradiol (E2) and progesterone (P4) will be assessed three times, on the same days as the endometrial peristalsis measurements, using electrochemiluminescence immunoassays. (Elecsys® Estradiol III and Elecsys® Progesterone III, Cobas® e 411, Roche Diagnostics, Germany):

• On the second day to the fourth day of the menstrual cycle in the FET cycles
• The day of hCG trigger
• On the transfer day prior to the procedure.

• Live birth was defined as the complete expulsion or extraction from a woman of a product of fertilization, after 22 completed weeks of gestational age; which, after such separation, breathes or shows any other evidence of life, such as heartbeat, umbilical cord pulsation, or definite movement of voluntary muscles, irrespective of whether the umbilical cord has been cut or the placenta is attached. A birth weight of 500 grams or more can be used if gestational age is unknown. Live births refer to the individual newborn; for example, a twin delivery represents two live births.
• Uterine contraction frequency is defined as the number of peristaltic waves per minute.