Eccentric Exercise in Community-dwelling Older Adults (HEX:AGEUK)
The Effects of an Eccentric-biased Strengthening Programme Delivered to Community-dwelling Older Adults"
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of a 12-month eccentric-biased strengthening programme in community-dwelling older adults aged 65 years and older. The main questions it aims to answer are:
Can an eccentric-biased strengthening programme be feasibly delivered to community-dwelling older adults in a community setting? Does participation in the programme improve functional mobility, lower-limb strength, falls self-efficacy, and health-related quality of life?
Participants will:
Attend a 12-month supervised eccentric-biased strengthening programme delivered in a community setting.
Complete assessments of functional mobility, lower-limb strength, falls self-efficacy, and health-related quality of life before and after the intervention.
Provide information regarding their experience of participating in the programme to evaluate its acceptability.
연구 개요
상태
상태
정황
정황
개입 / 치료
개입 / 치료
상세 설명
Age-related declines in muscle strength, power, and physical function contribute to reduced mobility, loss of independence, and an increased risk of falls among older adults. Resistance exercise is recommended to mitigate these declines; however, conventional exercise programmes may be limited by physical capacity, fatigue, or accessibility. Eccentric muscle actions allow greater force production at a lower metabolic cost and may therefore represent an effective and practical training modality for older adults.
This study will evaluate the feasibility, acceptability, and preliminary effectiveness of a community-based eccentric-biased strengthening programme delivered to community-dwelling older adults. Participants will be recruited through community organisations and complete a 12-month supervised exercise intervention designed to improve lower-limb strength and functional performance.
Feasibility will be evaluated through recruitment, retention, attendance, adherence, and adverse event monitoring. Acceptability will be assessed through participant feedback and experiences of programme participation. Preliminary effectiveness will be explored through changes in measures of physical function, falls-related self-efficacy, and health-related quality of life collected before and after the intervention.
The findings will provide evidence regarding the practicality of delivering an eccentric-biased strengthening programme within a community setting and will inform the design of future adequately powered controlled studies investigating the effectiveness of eccentric exercise interventions in older adults.
연구 유형
연구 유형
등록 (추정된)
등록
단계
단계
- 해당 없음
연락처 및 위치
연구 연락처
연구 연락처
- 이름: Brett A Baxter, PhD
- 전화번호: 01604892293
- 이메일: brett.baxter@northampton.ac.uk
연구 연락처 백업
- 이름: Tony Kay, PhD
- 전화번호: 01604892577
- 이메일: tony.kay@northampton.ac.uk
연구 장소
-
-
Northamptonshire
-
Northampton, Northamptonshire, 영국, NN1 5PH
- University of Northampton
-
-
참여기준
자격 기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
Age ≥ 65 years Ambulant with or without a walking aid
Exclusion Criteria:
- Inability to provide informed consent, assessed using the Mental Capacity Act two-stage assessment
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 해당 없음
- 중재 모델: 단일 그룹 할당
- 마스킹: 없음(오픈 라벨)
팔의 수
무기와 개입
참가자 그룹 / 팔참가자 그룹 / 팔 |
개입 / 치료개입 / 치료 |
|---|---|
|
실험적: Intervention
Eccentric exercise programme |
Participants will undertake a 12-month supervised eccentric-biased strengthening programme delivered in a community setting, with the option of performing this at home. The intervention will consist of 6x 1-minute progressive lower-limb strengthening exercises emphasising the eccentric phase of movement, including functional tasks relevant to activities of daily living. Exercise difficulty will be progressively increased throughout the programme according to participant performance and tolerance. Community sessions will be led by staff at the community setting who will have been educated and trained by developers of the exercise programme in a group-based format. The intervention is designed to improve lower-limb strength, mobility, balance confidence, and physical function in community-dwelling older adults. |
연구는 무엇을 측정합니까?
주요 결과 측정
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Feasibility of Intervention Recruitment
기간: Up to 12 months
|
Feasibility of recruitment will be assessed through participant recruitment capacity, calculated as the number of participants enrolled on the study relative to total number of people invited to take part. |
Up to 12 months
|
|
Feasibility of Intervention Delivery
기간: Up to 12 months
|
Feasibility of delivery will be assessed through participant partiicpant adherence to the intervention, calculated as the number of sessions attended relative to the total number of sessions presrcibed. |
Up to 12 months
|
2차 결과 측정
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Timed Up and Go Test
기간: Up to 12 months
|
Timed Up and Go test wil require participants to rise from a chair, walk three metres, turn around, return to the chair, and sit down. The time taken to complete the test will be recorded in seconds. |
Up to 12 months
|
|
Sit-to-stand Test
기간: Up to 12 months
|
Lower-limb strength will be assessed using the Five Times Sit-to-Stand test. Participants will be asked to stand up and sit down five times as quickly as possible from a standard chair without using their arms for assistance. Time to completion will be recorded in seconds. |
Up to 12 months
|
|
Falls Efficacy Scale International
기간: Up to 12 months
|
The Falls Efficacy Scale International (FES-I) will be used to assess the fear of falling. The FES-I is a validated self-report questionnaire that evaluates an individual's concern about falling during a range of everyday activities. Higher scores indicate greater concern about falling. |
Up to 12 months
|
|
EuroQol Five-Dimension Five-Level Questionnaire
기간: Up to 12 months
|
Health-related quality of life will be assessed using the EQ-5D-5L questionnaire. The instrument evaluates mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, alongside a self-rated health visual analogue scale. |
Up to 12 months
|
|
Intervention Acceptability
기간: Up to 12 months
|
Participant acceptability of the eccentric-biased strengthening programme will be assessed through post-intervention feedback. Information regarding participant satisfaction, perceived benefits, barriers to participation, and willingness to continue exercise following programme completion will be collected. |
Up to 12 months
|
공동 작업자 및 조사자
수사관
수사관
- 수석 연구원: Brett A. Baxter, PhD, University of Northampton
연구 기록 날짜
연구 주요 날짜
연구 시작 (추정된)
연구 시작
기본 완료 (추정된)
기본 완료
연구 완료 (추정된)
연구 완료
연구 등록 날짜
최초 제출
최초 제출
QC 기준을 충족하는 최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
처음 게시됨
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
마지막 업데이트 게시됨
QC 기준을 충족하는 마지막 업데이트 제출
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
기타 연구 ID 번호
- FHSHEA000518
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
IPD 계획 설명
De-identified individual participant data for all primary and secondary outcome measures reported in study publications will be made available. This includes baseline and post-intervention values for TUG, 5×STS, Short FES-I, EQ-5D-5L, and intervention adherence metrics. No personally identifiable information will be shared.
IPD 공유 기간
IPD will be available indefinitely as it will be stored on a public resposiotory (PURE).
IPD 공유 액세스 기준
Public
IPD 공유 지원 정보 유형
- 연구_프로토콜
- 수액
연구 데이터/문서
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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