MCRPC(MK-5684-003)에서 MK-5684 대 대체 NHA에 대한 연구 (OMAHA-003)
2026년 11월 4일 업데이트: Merck Sharp & Dohme LLC
이전에 차세대 호르몬제(NHA) 및 탁산 기반 화학요법으로 치료받은 전이성 거세저항성 전립선암(mCRPC) 참가자를 대상으로 MK-5684 대 대체 아비라테론 아세테이트 또는 엔잘루타마이드의 제3상 무작위 공개 라벨 연구
This is a phase 3, randomized, open-label study of opevesostat compared to alternative abiraterone acetate or enzalutamide in participants with metastatic castration-resistant prostate cancer (mCRPC) with respect to overall survival (OS) in participants with mCRPC previously treated with next-generation hormonal agent (NHA) and taxane-based chemotherapy. It is hypothesized that opevesostat is superior with respect to OS in androgen receptor ligand binding domain (AR LBD) mutation-negative and -positive participants.
연구 개요
상태
모병
정황
연구 유형
중재적
등록 (추정된)
1310
단계
- 3단계
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 연락처
- 이름: Toll Free Number
- 전화번호: 1-888-577-8839
- 이메일: Trialsites@msd.com
연구 장소
-
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Gelderland
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Nijmegen, Gelderland, 네덜란드, 6525 GA
- 모병
- Radboudumc-Medical Oncology ( Site 1152)
-
연락하다:
- Study Coordinator
- 전화번호: +31 (0)24 361 0353
-
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Limburg
-
Sittard-Geleen, Limburg, 네덜란드, 6162 BG
- 모병
- Zuyderland Medical Centre-Trialbureau Interne Geneeskunde ( Site 1163)
-
연락하다:
- Study Coordinator
- 전화번호: +31884599740
-
Venlo, Limburg, 네덜란드, 5912 BL
- 완전한
- VieCuri Medisch Centrum ( Site 1173)
-
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North Brabant
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Tilburg, North Brabant, 네덜란드, 5022 GC
- 모병
- ETZ Elisabeth-Internal Medicine ( Site 1160)
-
연락하다:
- Study Coordinator
- 전화번호: +3113221 0210
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North Holland
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Amsterdam, North Holland, 네덜란드, 1066 CX
- 모병
- Nederlands Kanker Instituut - Antoni van Leeuwenhoek - NKI-AVL ( Site 1153)
-
연락하다:
- Study Coordinator
- 전화번호: +31205122569
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Amsterdam, North Holland, 네덜란드, 1081 HV
- 완전한
- Amsterdam UMC, locatie VUmc ( Site 1156)
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Hoofddorp, North Holland, 네덜란드, 2134 TM
- 모집하지 않고 적극적으로
- Spaarne Gasthuis - Hoofddorp-Oncology ( Site 1170)
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Provincie Friesland
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Leeuwarden, Provincie Friesland, 네덜란드, 8934 AD
- 모집하지 않고 적극적으로
- Medische Centrum Leeuwarden ( Site 1172)
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South Holland
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Schiedam, South Holland, 네덜란드, 3118 JH
- 모병
- Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 1151)
-
연락하다:
- Study Coordinator
- 전화번호: 003110- 4617590
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The Hague, South Holland, 네덜란드, 2545 AA
- 모병
- Haga Ziekenhuis locatie Leyweg-Oncology ( Site 1164)
-
연락하다:
- Study Coordinator
- 전화번호: +31702102143
-
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Utrecht
-
Amersfoort, Utrecht, 네덜란드, 3813 TZ
- 모병
- Meander Medisch Centrum ( Site 1157)
-
연락하다:
- Study Coordinator
- 전화번호: +003133 - 850 1189
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Akershus
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Lørenskog, Akershus, 노르웨이, 1474
- 모병
- Akershus Universitetssykehus-Onkologisk avdeling ( Site 1227)
-
연락하다:
- Study Coordinator
- 전화번호: +4767963800
-
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Sor-Trondelag
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Trondheim, Sor-Trondelag, 노르웨이, 7030
- 모집하지 않고 적극적으로
- St. Olavs Hospital-Kreftklinikken ( Site 1231)
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Østfold fylke
-
Sarpsborg, Østfold fylke, 노르웨이, 1714
- 완전한
- Sykehuset Østfold Kalnes ( Site 1228)
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Bay of Plenty
-
Tauranga, Bay of Plenty, 뉴질랜드, 3112
- 모병
- Tauranga Hospital-Bay of Plenty Clinical Trials Unit ( Site 1201)
-
연락하다:
- Study Coordinator
- 전화번호: +64277033845
-
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Otago
-
Dunedin, Otago, 뉴질랜드, 9016
- 모병
- Dunedin Hospital-Southern Blood and Cancers Service ( Site 1203)
-
연락하다:
- Study Coordinator
- 전화번호: +64 3 470 9692
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-
-
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Taichung, 대만, 40447
- 모병
- China Medical University Hospital-Department of Urology ( Site 1503)
-
연락하다:
- Study Coordinator
- 전화번호: +886-4-2205-2121
-
Tainan, 대만, 704
- 모병
- National Cheng Kung University Hospital-Urology ( Site 1502)
-
연락하다:
- Study Coordinator
- 전화번호: +886-6-2353535
-
Taipei, 대만, 112
- 모병
- Taipei Veterans General Hospital ( Site 1505)
-
연락하다:
- Study Coordinator
- 전화번호: +886-2-28712121
-
Taipei, 대만, 10002
- 모병
- National Taiwan University Hospital-Urology ( Site 1506)
-
연락하다:
- Study Coordinator
- 전화번호: +886-2-2312-3456
-
Taoyuan, 대만, 333
- 모병
- Chang Gung Medical Foundation-Linkou Branch-Medical Oncology ( Site 1504)
-
연락하다:
- Study Coordinator
- 전화번호: +886-3-3281200
-
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Seoul, 대한민국, 06351
- 모병
- Samsung Medical Center ( Site 1405)
-
연락하다:
- Study Coordinator
- 전화번호: +82234101767
-
Seoul, 대한민국, 03080
- 모병
- Seoul National University Hospital-Oncology ( Site 1401)
-
연락하다:
- Study Coordinator
- 전화번호: +82220721672
-
Seoul, 대한민국, 03722
- 모병
- Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1404)
-
연락하다:
- Study Coordinator
- 전화번호: +82222288138
-
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Seoul
-
Songpagu, Seoul, 대한민국, 05505
- 모병
- Asan Medical Center-Oncology ( Site 1402)
-
연락하다:
- Study Coordinator
- 전화번호: +82230106095
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Capital Region
-
Copenhagen, Capital Region, 덴마크, 2100
- 모병
- Rigshospitalet ( Site 0576)
-
연락하다:
- Study Coordinator
- 전화번호: +45 35453545
-
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Region Syddanmark
-
Odense, Region Syddanmark, 덴마크, 5000
- 모집하지 않고 적극적으로
- Odense Universitetshospital-Department of oncology ( Site 0579)
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Vejle, Region Syddanmark, 덴마크, 7100
- 모병
- Vejle Sygehus ( Site 0578)
-
연락하다:
- Study Coordinator
- 전화번호: +45 79405000
-
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-
-
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Berlin, 독일, 10117
- 모병
- Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0679)
-
연락하다:
- Study Coordinator
- 전화번호: 0049 30 450615285
-
Hamburg, 독일, 20246
- 모병
- Universitaetsklinikum Hamburg-Eppendorf-Onkologisches Zentrum ( Site 0705)
-
연락하다:
- Study Coordinator
- 전화번호: +4915222815585
-
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Bavaria
-
Munich, Bavaria, 독일, 81675
- 모집하지 않고 적극적으로
- klinikum rechts der isar der technischen universität münchen-Urologische Klinik und Poliklinik ( Site 0696)
-
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Mecklenburg-Vorpommern
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Schwerin, Mecklenburg-Vorpommern, 독일, 19055
- 모병
- HELIOS Kliniken Schwerin ( Site 0694)
-
연락하다:
- Study Coordinator
- 전화번호: +493855202120
-
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North Rhine-Westphalia
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Bonn, North Rhine-Westphalia, 독일, 53127
- 모병
- Universitätsklinikum Bonn-Klinik und Poliklinik für Urologie und Kinderurologie ( Site 0680)
-
연락하다:
- Study Coordinator
- 전화번호: +4922828714249
-
Münster, North Rhine-Westphalia, 독일, 48149
- 모병
- Universitätsklinikum Münster - Albert Schweitzer Campus-Klinik für Urologie ( Site 0678)
-
연락하다:
- Study Coordinator
- 전화번호: 0049251-8344658
-
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Schleswig-Holstein
-
Lübeck, Schleswig-Holstein, 독일, 23538
- 모병
- Universitätsklinikum Schleswig-Holstein-Klinik für Urologie ( Site 0691)
-
연락하다:
- Study Coordinator
- 전화번호: +4945150043699
-
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Thuringia
-
Jena, Thuringia, 독일, 07747
- 모병
- Universitätsklinikum Jena-Klinik und Poliklinik für Urologie ( Site 0682)
-
연락하다:
- Study Coordinator
- 전화번호: +49 3641 9 32 9947
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-
-
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Kuala Lumpur, 말레이시아, 50586
- 모병
- Hospital Kuala Lumpur-Radiotherapy and Oncology ( Site 1078)
-
연락하다:
- Study Coordinator
- 전화번호: +60326155810
-
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Johor
-
Johor Bahru, Johor, 말레이시아, 81100
- 모병
- Hospital Sultan Ismail ( Site 1081)
-
연락하다:
- Study Coordinator
- 전화번호: +6073565155
-
-
Kuala Lumpur
-
Lembah Pantai, Kuala Lumpur, 말레이시아, 59100
- 완전한
- University Malaya Medical Centre ( Site 1077)
-
-
Putrajaya
-
Putrajaya, Putrajaya, 말레이시아, 62250
- 모병
- National Cancer Institute ( Site 1079)
-
연락하다:
- Study Coordinator
- 전화번호: +60388925418
-
-
Sarawak
-
Kuching, Sarawak, 말레이시아, 93586
- 모병
- Sarawak General Hospital-Radiotherapy Unit ( Site 1076)
-
연락하다:
- Study Coordinator
- 전화번호: +6082276820
-
-
-
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Jalisco
-
Guadalajara, Jalisco, 멕시코, 44630
- 모병
- CIO - Centro de Inmuno-Oncología de Occidente ( Site 1103)
-
연락하다:
- Study Coordinator
- 전화번호: +52 3313587270
-
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Mexico City
-
Mexico City, Mexico City, 멕시코, 14308
- 모병
- Quemex Medical and Research ( Site 1112)
-
연락하다:
- Study Coordinator
- 전화번호: +52555673461
-
Mexico City, Mexico City, 멕시코, 68020
- 모병
- Centro de Investigacion Clinica de Oaxaca ( Site 1109)
-
연락하다:
- Study Coordinator
- 전화번호: +529515473137
-
-
Nuevo León
-
Monterrey, Nuevo León, 멕시코, 64460
- 모병
- Filios Alta Medicina ( Site 1106)
-
연락하다:
- Study Coordinator
- 전화번호: +528110623583
-
Monterrey, Nuevo León, 멕시코, 64460
- 모병
- Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 1107)
-
연락하다:
- Study Coordinator
- 전화번호: +528183338111 Ext.9
-
-
Yucatán
-
Mérida, Yucatán, 멕시코, 97070
- 완전한
- Medical Care and Research SA de CV ( Site 1108)
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-
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California
-
Orange, California, 미국, 92868
- 완전한
- University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0040)
-
Palo Alto, California, 미국, 94304
- 모병
- Stanford Cancer Center ( Site 0036)
-
연락하다:
- Study Coordinator
- 전화번호: 650-725-2078
-
Riverside, California, 미국, 92505
- 모병
- Kaiser Permanente Riverside Medical Center ( Site 0099)
-
연락하다:
- Study Coordinator
- 전화번호: 951-809-8361
-
-
Colorado
-
Aurora, Colorado, 미국, 80045
- 모병
- Anschutz Cancer Pavilion ( Site 0046)
-
연락하다:
- Study Coordinator
- 전화번호: 302-290-3598
-
Highlands Ranch, Colorado, 미국, 80129
- 모병
- University of Colorado Health - Highlands Ranch Hospital ( Site 0111)
-
연락하다:
- Study Coordinator
- 전화번호: 302-290-3598
-
Lakewood, Colorado, 미국, 80228
- 완전한
- Colorado Clinical Research ( Site 0067)
-
Lone Tree, Colorado, 미국, 80124
- 모병
- University of Colorado Health - Lone Tree Medical Center ( Site 0112)
-
연락하다:
- Study Coordinator
- 전화번호: 720-848-5146
-
-
Connecticut
-
New Haven, Connecticut, 미국, 06510
- 모병
- Yale-New Haven Hospital-Yale Cancer Center ( Site 0064)
-
연락하다:
- Study Coordinator
- 전화번호: 203-737-8076
-
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Florida
-
Fort Myers, Florida, 미국, 33901
- 완전한
- Florida Cancer Specialists - South ( Site 7003)
-
Miami, Florida, 미국, 33136
- 모병
- University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 0051)
-
연락하다:
- Study Coordinator
- 전화번호: 305-243-1543
-
Miami, Florida, 미국, 33125
- 완전한
- Bruce W. Carter Veterans Affairs Medical Center ( Site 0082)
-
-
Illinois
-
Chicago, Illinois, 미국, 60637
- 모병
- University of Chicago Medical Center ( Site 0045)
-
연락하다:
- Study Coordinator
- 전화번호: 773-702-7609
-
Chicago, Illinois, 미국, 60612
- 모병
- University of Illinois at Chicago ( Site 0105)
-
연락하다:
- Study Coordinator
- 전화번호: 973-330-2391
-
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Iowa
-
Iowa City, Iowa, 미국, 52242
- 완전한
- University of Iowa ( Site 0047)
-
-
Kentucky
-
Lexington, Kentucky, 미국, 40536
- 완전한
- University of Kentucky Chandler Medical Center ( Site 0048)
-
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Louisiana
-
New Orleans, Louisiana, 미국, 70121
- 완전한
- Ochsner Clinic Foundation ( Site 0108)
-
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Maryland
-
Baltimore, Maryland, 미국, 21201
- 모병
- Baltimore Veterans Affairs Medical Center ( Site 0069)
-
연락하다:
- Study Coordinator
- 전화번호: 410-707-4011
-
Baltimore, Maryland, 미국, 21201
- 모병
- Greenebaum Comprehensive Cancer Center ( Site 0049)
-
연락하다:
- Study Coordinator
- 전화번호: 410-707-4011
-
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Michigan
-
Detroit, Michigan, 미국, 48202
- 완전한
- Henry Ford Hospital ( Site 0015)
-
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Minnesota
-
Marshall, Minnesota, 미국, 56258
- 모병
- Avera Cancer Institute - Marshall ( Site 0122)
-
연락하다:
- Study Coordinator
- 전화번호: 605-601-1830
-
Minneapolis, Minnesota, 미국, 55455
- 모병
- M Health Fairview Clinics and Surgery Center ( Site 0019)
-
연락하다:
- Study Coordinator
- 전화번호: 612-626-1422
-
Saint Louis Park, Minnesota, 미국, 55416
- 모집하지 않고 적극적으로
- Metro-Minnesota Community Clinical Oncology ( Site 0014)
-
-
Mississippi
-
Hattiesburg, Mississippi, 미국, 39401
- 모병
- Hattiesburg Clinic Hematology/Oncology ( Site 0120)
-
연락하다:
- Study Coordinator
- 전화번호: 601-261-1700
-
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Missouri
-
St Louis, Missouri, 미국, 63110
- 모병
- Washington University School of Medicine-Internal Medicine/Oncology ( Site 0062)
-
연락하다:
- Study Coordinator
- 전화번호: 314-286-2341
-
-
Nebraska
-
Omaha, Nebraska, 미국, 68105
- 모병
- University Of Nebraska Medical Center-Oncology/Hematology ( Site 0095)
-
연락하다:
- Study Coordinator
- 전화번호: 402-559-8500
-
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Nevada
-
Las Vegas, Nevada, 미국, 89148
- 모병
- Comprehensive Cancer Centers of Nevada ( Site 0010)
-
연락하다:
- Study Coordinator
- 전화번호: 702-952-1251
-
-
New Jersey
-
Morristown, New Jersey, 미국, 07960
- 모병
- Atlantic Health System Morristown Medical Center ( Site 0115)
-
연락하다:
- Study Coordinator
- 전화번호: 973-971-7960
-
New Brunswick, New Jersey, 미국, 08903
- 완전한
- Rutgers Cancer Institute of New Jersey ( Site 0033)
-
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New York
-
The Bronx, New York, 미국, 10468
- 모병
- James J. Peters VA Medical Center ( Site 0088)
-
연락하다:
- Study Coordinator
- 전화번호: 718-584-9000
-
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Ohio
-
Cleveland, Ohio, 미국, 44106
- 모병
- University Hospitals Cleveland Medical Center ( Site 0043)
-
연락하다:
- Study Coordinator
- 전화번호: 216-844-3951
-
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Oregon
-
Portland, Oregon, 미국, 97239
- 모병
- VA Portland Health Care System ( Site 0058)
-
연락하다:
- Study Coordinator
- 전화번호: 503-220-8262
-
Portland, Oregon, 미국, 97239
- 완전한
- Oregon Health and Science University ( Site 0028)
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Pennsylvania
-
Pittsburgh, Pennsylvania, 미국, 15212
- 완전한
- AHN Allegheny General Hospital ( Site 0001)
-
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South Carolina
-
Charleston, South Carolina, 미국, 29401
- 완전한
- Ralph H. Johnson VA Health Care System (RHJVAHCS)-Urology ( Site 0083)
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South Dakota
-
Aberdeen, South Dakota, 미국, 57401
- 모병
- Avera Cancer Institute - Aberdeen ( Site 0123)
-
연락하다:
- Study Coordinator
- 전화번호: 605-601-1830
-
Mitchell, South Dakota, 미국, 57301
- 모병
- Avera Cancer Institute - Mitchell ( Site 0121)
-
연락하다:
- Study Coordinator
- 전화번호: 605-601-1830
-
Pierre, South Dakota, 미국, 57501
- 모병
- Avera Cancer Institute - Pierre ( Site 0118)
-
연락하다:
- Study Coordinator
- 전화번호: 605-224-3370
-
Sioux Falls, South Dakota, 미국, 57105
- 모병
- Avera Cancer Institute- Research ( Site 0094)
-
연락하다:
- Study Coordinator
- 전화번호: 605-322-6900
-
Yankton, South Dakota, 미국, 57078
- 모병
- Avera Cancer Institute - Yankton ( Site 0117)
-
연락하다:
- Study Coordinator
- 전화번호: 605-655-1800
-
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Tennessee
-
Nashville, Tennessee, 미국, 37203
- 모병
- SCRI Oncology Partners ( Site 7000)
-
연락하다:
- Study Coordinator
- 전화번호: 615-218-4647
-
-
Texas
-
Austin, Texas, 미국, 78731
- 모병
- Texas Oncology - Central/South Texas ( Site 8003)
-
연락하다:
- Study Coordinator
- 전화번호: 512-427-9400
-
Dallas, Texas, 미국, 75246
- 완전한
- Texas Oncology - DFW ( Site 8001)
-
Houston, Texas, 미국, 77024
- 모병
- Texas Oncology - Gulf Coast ( Site 8002)
-
연락하다:
- Study Coordinator
- 전화번호: 713-467-1722
-
-
Virginia
-
Charlottesville, Virginia, 미국, 22908
- 모병
- University of Virginia Health System ( Site 0054)
-
연락하다:
- Study Coordinator
- 전화번호: 434-327-3029
-
Richmond, Virginia, 미국, 23219
- 완전한
- VCU Health Adult Outpatient Pavillion ( Site 0061)
-
Roanoke, Virginia, 미국, 24014
- 모병
- Blue Ridge Cancer Care ( Site 0004)
-
연락하다:
- Study Coordinator
- 전화번호: 540-982-0237
-
-
Washington
-
Seattle, Washington, 미국, 98109
- 모병
- Fred Hutchinson Cancer Center ( Site 0013)
-
연락하다:
- Study Coordinator
- 전화번호: 617-413-9079
-
-
Wisconsin
-
Milwaukee, Wisconsin, 미국, 53226
- 모병
- Medical College of Wisconsin ( Site 0020)
-
연락하다:
- Study Coordinator
- 전화번호: 414-805-4600
-
-
-
-
Espírito Santo
-
Vitória, Espírito Santo, 브라질, 29041-295
- 모병
- Hospital Santa Rita de Cassia-Centro de Pesquisa Clínica ( Site 0320)
-
연락하다:
- Study Coordinator
- 전화번호: +55 27 3334-8346
-
-
Estado de Bahia
-
Salvador, Estado de Bahia, 브라질, 41680-430
- 모병
- Obras Sociais Irma Dulce ( Site 0302)
-
연락하다:
- Study Coordinator
- 전화번호: +55 71 3310-1978
-
-
Minas Gerais
-
Belo Horizonte, Minas Gerais, 브라질, 30110-934
- 모병
- Hospital Felicio Rocho ( Site 0317)
-
연락하다:
- Study Coordinator
- 전화번호: +55 31 35147195
-
Belo Horizonte, Minas Gerais, 브라질, 30380-472
- 모병
- Hospital Mario Penna ( Site 0309)
-
연락하다:
- Study Coordinator
- 전화번호: +551 31 3299-9543
-
-
Paraná
-
Curitiba, Paraná, 브라질, 80440-220
- 모병
- Hospital Universitário Evangélico Mackenzie-Centro de Oncologia Mackenzie ( Site 0314)
-
연락하다:
- Study Coordinator
- 전화번호: 5541991681411
-
-
Santa Catarina
-
Itajaí, Santa Catarina, 브라질, 88301-220
- 모병
- Clínica de Neoplasias Litoral ( Site 0305)
-
연락하다:
- Study Coordinator
- 전화번호: +5547984046243
-
-
São Paulo
-
Bragança Paulista, São Paulo, 브라질, 12916-542
- 모병
- Hospital Universitário São Francisco de Assis - Bragança Paulista ( Site 0308)
-
연락하다:
- Study Coordinator
- 전화번호: +55 11 98337-1381
-
São Paulo, São Paulo, 브라질, 01509-010
- 모집하지 않고 적극적으로
- A. C. Camargo Cancer Center ( Site 0310)
-
-
-
-
Stockholm County
-
Stockholm, Stockholm County, 스웨덴, 171 64
- 모집하지 않고 적극적으로
- Karolinska Universitetssjukhuset Solna ( Site 1478)
-
-
Uppsala County
-
Uppsala, Uppsala County, 스웨덴, 751 85
- 모병
- Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 1477)
-
연락하다:
- Study Coordinator
- 전화번호: 0046186110000
-
-
Västra Götaland County
-
Gothenburg, Västra Götaland County, 스웨덴, 413 45
- 모병
- Sahlgrenska Universitetssjukhuset ( Site 1479)
-
연락하다:
- Study Coordinator
- 전화번호: 0046313421000
-
-
-
-
-
Lugo, 스페인, 27003
- 모병
- Hospital Lucus Augusti-Oncology ( Site 1432)
-
연락하다:
- Study Coordinator
- 전화번호: +34982296459
-
Seville, 스페인, 41013
- 모병
- HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 1428)
-
연락하다:
- Study Coordinator
- 전화번호: 34955013068
-
-
Cadiz
-
Jerez de la Frontera, Cadiz, 스페인, 11407
- 모병
- Hospital Jerez de la Frontera ( Site 1427)
-
연락하다:
- Study Coordinator
- 전화번호: +34661753582
-
-
Madrid, Comunidad de
-
Madrid, Madrid, Comunidad de, 스페인, 28034
- 모병
- Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 1431)
-
연락하다:
- Study Coordinator
- 전화번호: 34913368263
-
Madrid, Madrid, Comunidad de, 스페인, 28041
- 모병
- Hospital Universitario 12 de Octubre-Medical Oncology ( Site 1433)
-
연락하다:
- Study Coordinator
- 전화번호: 608464547
-
-
Orense
-
Ourense, Orense, 스페인, 32005
- 모병
- Complexo Hospitalario Universitario de Ourense ( Site 1426)
-
연락하다:
- Study Coordinator
- 전화번호: +34988385471
-
-
Valenciana, Comunitat
-
Valencia, Valenciana, Comunitat, 스페인, 46009
- 모병
- Fundación Instituto Valenciano de Oncología-Oncologico ( Site 1430)
-
연락하다:
- Study Coordinator
- 전화번호: +34 961114229
-
-
-
-
Central Singapore
-
Singapore, Central Singapore, 싱가포르, 168583
- 모병
- National Cancer Centre Singapore ( Site 1377)
-
연락하다:
- Study Coordinator
- 전화번호: +65-64368000
-
Singapore, Central Singapore, 싱가포르, 308433
- 모병
- Tan Tock Seng Hospital-Medical Oncology ( Site 1378)
-
연락하다:
- Study Coordinator
- 전화번호: +65-62566011
-
Singapore, Central Singapore, 싱가포르, 119074
- 모병
- National University Hospital ( Site 1376)
-
연락하다:
- Study Coordinator
- 전화번호: 6569082222
-
-
-
-
-
Buenos Aires, 아르헨티나, C1118AAT
- 모집하지 않고 적극적으로
- Hospital Aleman-Oncology ( Site 0207)
-
Mendoza, 아르헨티나, M5500AYB
- 모병
- Fundacion Centro Oncologico de Integración Regional-Medical Oncology ( Site 0204)
-
연락하다:
- Study Coordinator
- 전화번호: +5492615449901
-
-
Buenos Aires
-
Ciudad Autónoma de Buenos Aires, Buenos Aires, 아르헨티나, C1280AEB
- 모집하지 않고 적극적으로
- Hospital Británico de Buenos Aires-Oncology ( Site 0202)
-
Mar del Plata, Buenos Aires, 아르헨티나, B7600FZO
- 모집하지 않고 적극적으로
- Instituto de Investigaciones Clínicas Mar del Plata ( Site 0201)
-
-
Buenos Aires F.D.
-
Buenos Aires, Buenos Aires F.D., 아르헨티나, C1419AHN
- 모병
- Asociación de Beneficencia Hospital Sirio Libanés ( Site 0205)
-
연락하다:
- Study Coordinator
- 전화번호: +5491145744343
-
Buenos Aires, Buenos Aires F.D., 아르헨티나, C1426ANZ
- 모병
- Instituto Alexander Fleming-Alexander Fleming ( Site 0206)
-
연락하다:
- Study Coordinator
- 전화번호: +5491132218900
-
-
Santa Fe Province
-
Rosario, Santa Fe Province, 아르헨티나, S2000DSV
- 모병
- Sanatorio Parque ( Site 0208)
-
연락하다:
- Study Coordinator
- 전화번호: +5493414200222
-
-
-
-
-
Dublin, 아일랜드, D24 NR0A
- 모병
- Tallaght University Hospital ( Site 0801)
-
연락하다:
- Study Coordinator
- 전화번호: +35314144299
-
-
Dublin
-
Dublin, Dublin, 아일랜드, D04 T6F4
- 모병
- St. Vincent's University Hospital ( Site 0802)
-
연락하다:
- Study Coordinator
- 전화번호: +35312214000
-
-
-
-
-
Manchester, 영국, m20 4bx
- 모병
- The Christie NHS Foundation Trust ( Site 1608)
-
연락하다:
- Study Coordinator
- 전화번호: +441614463000
-
-
Cambridgeshire
-
Cambridge, Cambridgeshire, 영국, CB2 2QQ
- 모병
- Addenbrooke's Hospital ( Site 1605)
-
연락하다:
- Study Coordinator
- 전화번호: 01223216083
-
-
England
-
Truro, England, 영국, TR1 3LJ
- 모병
- The Royal Cornwall Hospital ( Site 1610)
-
연락하다:
- Study Coordinator
- 전화번호: 01872258345
-
-
Glasgow City
-
Glasgow, Glasgow City, 영국, G12 0YN
- 모병
- The Beatson West of Scotland Cancer Centre ( Site 1603)
-
연락하다:
- Study Coordinator
- 전화번호: +441413017000
-
-
Hammersmith and Fulham
-
London, Hammersmith and Fulham, 영국, W6 8RF
- 모병
- Charing Cross Hospital-Oncology Research ( Site 1606)
-
연락하다:
- Study Coordinator
- 전화번호: 0208 331 10277
-
-
London, City of
-
London, London, City of, 영국, NW1 2PG
- 모병
- University College London Hospital ( Site 1612)
-
연락하다:
- Study Coordinator
- 전화번호: 0203 447 3042
-
-
-
-
Styria
-
Graz, Styria, 오스트리아, 8036
- 모병
- Medizinische Universität Graz-Innere Medizin Klin. Abt. Onkologie ( Site 0280)
-
연락하다:
- Study Coordinator
- 전화번호: +4331638581307
-
-
Upper Austria
-
Linz, Upper Austria, 오스트리아, 4020
- 모병
- Ordensklinikum Linz GmbH Elisabethinen-Urologie ( Site 0276)
-
연락하다:
- Study Coordinator
- 전화번호: +4373276774724
-
Wels, Upper Austria, 오스트리아, 4600
- 모병
- Klinikum Wels-Grieskirchen GmbH ( Site 0279)
-
연락하다:
- Study Coordinator
- 전화번호: +4372424152328
-
-
-
-
-
Afula, 이스라엘, 1834111
- 모병
- Emek Medical Center ( Site 0830)
-
연락하다:
- Study Coordinator
- 전화번호: 0546708579
-
Haifa, 이스라엘, 3109601
- 모병
- Rambam Health Care Campus-Oncology Division ( Site 0826)
-
연락하다:
- Study Coordinator
- 전화번호: 04-7776234
-
Jerusalem, 이스라엘, 9112001
- 모병
- Hadassah Medical Center ( Site 0833)
-
연락하다:
- Study Coordinator
- 전화번호: 02-6777111
-
Kfar Saba, 이스라엘, 4428164
- 모병
- Meir Medical Center. ( Site 0832)
-
연락하다:
- Study Coordinator
- 전화번호: 0503745684
-
Petah Tikva, 이스라엘, 4941492
- 모병
- Rabin Medical Center ( Site 0828)
-
연락하다:
- Study Coordinator
- 전화번호: 972-50-3745684
-
Ramat Gan, 이스라엘, 5265601
- 모병
- Sheba Medical Center ( Site 0827)
-
연락하다:
- Study Coordinator
- 전화번호: : +972-35302191
-
-
-
-
-
Milan, 이탈리아, 20132
- 모병
- Ospedale San Raffaele-Oncologia Medica ( Site 0876)
-
연락하다:
- Study Coordinator
- 전화번호: +390226435668
-
-
Emilia-Romagna
-
Meldola, Emilia-Romagna, 이탈리아, 47014
- 모병
- IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 0879)
-
연락하다:
- Study Coordinator
- 전화번호: +390543739100
-
-
Lombardy
-
Milan, Lombardy, 이탈리아, 20133
- 모병
- Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 0877)
-
연락하다:
- Study Coordinator
- 전화번호: 00390223903033
-
-
-
-
-
Akita, 일본, 010-8543
- 모병
- Akita University Hospital ( Site 0904)
-
연락하다:
- Study Coordinator
- 전화번호: +81188341111
-
Fukuoka, 일본, 812-8582
- 모병
- Kyushu University Hospital ( Site 0919)
-
연락하다:
- Study Coordinator
- 전화번호: +81926411151
-
Fukushima, 일본, 960-1295
- 모병
- Fukushima Medical University Hospital ( Site 0933)
-
연락하다:
- Study Coordinator
- 전화번호: +81245471111
-
Gifu, 일본, 501-1112
- 모병
- Gifu University Hospital ( Site 0910)
-
연락하다:
- Study Coordinator
- 전화번호: +81-58-230-6000
-
Hiroshima, 일본, 734-8551
- 모병
- Hiroshima University Hospital ( Site 0916)
-
연락하다:
- Study Coordinator
- 전화번호: +81-82-257-5555
-
Kagoshima, 일본, 890-8520
- 모병
- Kagoshima University Hospital ( Site 0929)
-
연락하다:
- Study Coordinator
- 전화번호: +81-99-275-5111
-
Kumamoto, 일본, 860-0008
- 모병
- National Hospital Organization Kumamoto Medical Center ( Site 0924)
-
연락하다:
- Study Coordinator
- 전화번호: +81963536501
-
Miyazaki, 일본, 880-8510
- 모병
- Miyazaki Prefectural Miyazaki Hospital ( Site 0927)
-
연락하다:
- Study Coordinator
- 전화번호: +81985244181
-
Miyazaki, 일본, 889-1692
- 모병
- University of Miyazaki Hospital ( Site 0926)
-
연락하다:
- Study Coordinator
- 전화번호: +81-98-585-1510
-
Nagano, 일본, 381-8551
- 모병
- Nagano Municipal Hospital ( Site 0932)
-
연락하다:
- Study Coordinator
- 전화번호: +81-26-295-1199
-
Ōita, 일본, 870-0263
- 모병
- National Hospital Organization Oita Medical Center ( Site 0925)
-
연락하다:
- Study Coordinator
- 전화번호: +81-97-593-1111
-
-
Chiba
-
Sakura, Chiba, 일본, 285-8741
- 모병
- Toho University Sakura Medical Center ( Site 0906)
-
연락하다:
- Study Coordinator
- 전화번호: +81434628811
-
-
Ehime
-
Tōon, Ehime, 일본, 791-0295
- 모병
- Ehime University Hospital ( Site 0918)
-
연락하다:
- Study Coordinator
- 전화번호: +81-89-964-5111
-
-
Fukuoka
-
Kitakyushu, Fukuoka, 일본, 807-8556
- 완전한
- Hospital of the University of Occupational and Environmental Health, Japan ( Site 0921)
-
Kurume, Fukuoka, 일본, 830-0011
- 모병
- Kurume University Hospital ( Site 0920)
-
연락하다:
- Study Coordinator
- 전화번호: +81-942-35-3311
-
-
Hokkaido
-
Asahikawa, Hokkaido, 일본, 078-8510
- 모병
- Asahikawa Medical University Hospital ( Site 0901)
-
연락하다:
- Study Coordinator
- 전화번호: +81-166-65-2111
-
Sapporo, Hokkaido, 일본, 060-8543
- 모병
- Sapporo Medical University Hospital ( Site 0902)
-
연락하다:
- Study Coordinator
- 전화번호: +81-11-611-2111
-
Sapporo, Hokkaido, 일본, 060-8648
- 모병
- Hokkaido University Hospital ( Site 0931)
-
연락하다:
- Study Coordinator
- 전화번호: +81117161161
-
-
Hyōgo
-
Kobe, Hyōgo, 일본, 650-0017
- 모병
- Kobe University Hospital ( Site 0914)
-
연락하다:
- Study Coordinator
- 전화번호: +81783825111
-
-
Ishikawa-ken
-
Mukai-awagasaki, Ishikawa-ken, 일본, 920-0265
- 모병
- Kanazawa Medical University Hospital ( Site 0909)
-
연락하다:
- Study Coordinator
- 전화번호: +81-76-286-3511
-
-
Kagawa-ken
-
Kita, Kagawa-ken, 일본, 761-0701
- 모병
- Kagawa University Hospital ( Site 0917)
-
연락하다:
- Study Coordinator
- 전화번호: +81878985111
-
-
Kanagawa
-
Yokohama, Kanagawa, 일본, 232-0024
- 모병
- Yokohama City University Medical Center ( Site 0908)
-
연락하다:
- Study Coordinator
- 전화번호: +81452615656
-
-
Nagasaki
-
Ōmura, Nagasaki, 일본, 856-8562
- 모병
- National Hospital Organization Nagasaki Medical Center ( Site 0923)
-
연락하다:
- Study Coordinator
- 전화번호: +81-957-52-3121
-
-
Nara
-
Kashihara, Nara, 일본, 634-8522
- 완전한
- Nara Medical University Hospital ( Site 0915)
-
-
Okinawa
-
Shimajiri, Okinawa, 일본, 901-0417
- 모병
- Nanbu Tokushukai Hospital ( Site 0930)
-
연락하다:
- Study Coordinator
- 전화번호: +81-98-998-3221
-
-
Osaka
-
Hirakata, Osaka, 일본, 573-1191
- 모병
- Kansai Medical University Hospital ( Site 0912)
-
연락하다:
- Study Coordinator
- 전화번호: +81-72-804-0101
-
Sakai, Osaka, 일본, 599-8247
- 모병
- Bell Land General Hospital ( Site 0913)
-
연락하다:
- Study Coordinator
- 전화번호: +81722342001
-
Suita, Osaka, 일본, 565-0871
- 모병
- The University of Osaka Hospital ( Site 0911)
-
연락하다:
- Study Coordinator
- 전화번호: +81668795111
-
-
Saga-ken
-
Saga, Saga-ken, 일본, 840-8571
- 모병
- Saga-Ken Medical Centre Koseikan ( Site 0922)
-
연락하다:
- Study Coordinator
- 전화번호: +81952242171
-
-
Tokyo
-
Minato, Tokyo, 일본, 105-8471
- 완전한
- The Jikei University Hospital ( Site 0907)
-
-
-
-
Anhui
-
Hefei, Anhui, 중국, 230000
- 모병
- Second Affiliated hospital of Anhui Medical University-Urology ( Site 0408)
-
연락하다:
- Study Coordinator
- 전화번호: +86 02782201756
-
-
Beijing Municipality
-
Beijing, Beijing Municipality, 중국, 100034
- 모병
- Peking University First Hospital-Urology ( Site 0390)
-
연락하다:
- Study Coordinator
- 전화번호: +86 (010) 64008229
-
Beijing, Beijing Municipality, 중국, 100050
- 모병
- Beijing Friendship Hospital Affiliate of Capital University ( Site 0396)
-
연락하다:
- Study Coordinator
- 전화번호: +86(010)63138375
-
Beijing, Beijing Municipality, 중국, 100142
- 모병
- Beijing Cancer hospital-Urinary Surgery ( Site 0395)
-
연락하다:
- Study Coordinator
- 전화번호: 86 010 8812 1122
-
-
Chongqing Municipality
-
Chongqing, Chongqing Municipality, 중국, 400030
- 모병
- Chongqing University Cancer Hospital ( Site 0416)
-
연락하다:
- Study Coordinator
- 전화번호: 02365075629
-
Chongqing, Chongqing Municipality, 중국, 400038
- 모병
- Southwest Hospital of Third Military Medical University ( Site 0420)
-
연락하다:
- Study Coordinator
- 전화번호: 023 68765878
-
Chongqing, Chongqing Municipality, 중국, 404100
- 모병
- Chongqing Three Gorges Central Hospital's ( Site 0426)
-
연락하다:
- Study Coordinator
- 전화번호: 023 58103150
-
Chongqing, Chongqing Municipality, 중국, 400010
- 모병
- The First Affiliated Hospital of Chongqing Medical University ( Site 0427)
-
연락하다:
- Study Coordinator
- 전화번호: 023 89012012
-
-
Fujian
-
Fuzhou, Fujian, 중국, 350005
- 모병
- The First Affiliated Hospital Of Fujian Medical University-Urology ( Site 0414)
-
연락하다:
- Study Coordinator
- 전화번호: +86059187983333
-
Xiamen, Fujian, 중국, 361003
- 모병
- The First Affiliated hospital of Xiamen University-Urology ( Site 0415)
-
연락하다:
- Study Coordinator
- 전화번호: 0592-2132222
-
-
Guangdong
-
Guangzhou, Guangdong, 중국, 511400
- 모병
- Sun Yat-sen University Cancer Center-Internal medicine ( Site 0413)
-
연락하다:
- Study Coordinator
- 전화번호: +8602087343533
-
Guangzhou, Guangdong, 중국, 510230
- 모병
- The First Affiliated Hospital of Guangzhou Medical University ( Site 0412)
-
연락하다:
- Study Coordinator
- 전화번호: +8602034294311
-
-
Hubei
-
Wuhan, Hubei, 중국, 430079
- 모병
- Hubei Cancer Hospital-Urinary surgery ( Site 0406)
-
연락하다:
- Study Coordinator
- 전화번호: 8613907110640
-
Wuhan, Hubei, 중국, 430000
- 모병
- Tongji Hospital Tongji Medical,Science & Technology ( Site 0407)
-
연락하다:
- Study Coordinator
- 전화번호: 027-83665555
-
-
Hunan
-
Changsha, Hunan, 중국, 410013
- 모병
- Hunan Cancer Hospital ( Site 0405)
-
연락하다:
- Study Coordinator
- 전화번호: 073189762270
-
-
Jiangsu
-
Huaian, Jiangsu, 중국, 223300
- 모병
- First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 0436)
-
연락하다:
- Study Coordinator
- 전화번호: 0517-80872519
-
Nanjing, Jiangsu, 중국, 210008
- 모병
- Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( Site 0377)
-
연락하다:
- Study Coordinator
- 전화번호: 025-83105910
-
Wuxi, Jiangsu, 중국, 214122
- 모병
- Affiliated hospital of Jiangnan university ( Site 0434)
-
연락하다:
- Study Coordinator
- 전화번호: 0510-88682957
-
-
Jiangxi
-
Nanchang, Jiangxi, 중국, 330029
- 모병
- Jiangxi Cancer Hospital ( Site 0386)
-
연락하다:
- Study Coordinator
- 전화번호: 86079188317256
-
-
Shaanxi
-
Xi'an, Shaanxi, 중국, 710061
- 모병
- The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 0393)
-
연락하다:
- Study Coordinator
- 전화번호: 029-85323112
-
Xi'an, Shaanxi, 중국, 710004
- 모병
- The Second Affiliated Hospital of Xi'an Jiaotong University ( Site 0394)
-
연락하다:
- Study Coordinator
- 전화번호: 029-87679000
-
-
Shandong
-
Yantai, Shandong, 중국, 264099
- 모병
- Yantai Yuhuangding Hospital ( Site 0397)
-
연락하다:
- Study Coordinator
- 전화번호: 86 0535 6691999
-
-
Shanghai Municipality
-
Shanghai, Shanghai Municipality, 중국, 200000
- 모병
- Fudan University Shanghai Cancer Center-Urology department ( Site 0376)
-
연락하다:
- Study Coordinator
- 전화번호: 021-38196379
-
Shanghai, Shanghai Municipality, 중국, 200041
- 모병
- Huadong Hospital Affiliated to Fudan University-Urology ( Site 0388)
-
연락하다:
- Study Coordinator
- 전화번호: 021-62483180
-
Shanghai, Shanghai Municipality, 중국, 200032
- 모병
- Zhongshan Hospital Fudan University ( Site 0430)
-
연락하다:
- Study Coordinator
- 전화번호: 021-31587858
-
-
Sichuan
-
Chengdu, Sichuan, 중국, 500643
- 모병
- The Third People's Hospital of Chengdu (CDTPH) ( Site 0428)
-
연락하다:
- Study Coordinator
- 전화번호: 67566947
-
Chengdu, Sichuan, 중국, 610041
- 모병
- West China Hospital, Sichuan University-Urology Surgery ( Site 0417)
-
연락하다:
- Study Coordinator
- 전화번호: +86028-85422114
-
Nanchong, Sichuan, 중국, 500643
- 모병
- Nanchong Central Hospital-urology ( Site 0422)
-
연락하다:
- Study Coordinator
- 전화번호: 08172606822
-
Suining, Sichuan, 중국, 629000
- 모병
- Suining Central Hospital ( Site 0437)
-
연락하다:
- Study Coordinator
- 전화번호: 08252292093
-
-
Tianjin Municipality
-
Tianjin, Tianjin Municipality, 중국, 300060
- 모병
- Tianjin Medical University Cancer Institute & Hospital ( Site 0392)
-
연락하다:
- Study Coordinator
- 전화번호: +862223340123
-
Tianjin, Tianjin Municipality, 중국, 300211
- 모병
- The Second Hospital of Tianjin Medical University ( Site 0391)
-
연락하다:
- Study Coordinator
- 전화번호: +8602288326748
-
-
Xinjiang
-
Ürümqi, Xinjiang, 중국, 830000
- 모병
- Xinjiang Medical University Cancer Hospital - Urumqi-Urology ( Site 0419)
-
연락하다:
- Study Coordinator
- 전화번호: 86 09917819156
-
-
Yunnan
-
Kunming, Yunnan, 중국, 650033
- 모병
- The Second Affiliated Hospital Of Kunming Medical University ( Site 0429)
-
연락하다:
- Study Coordinator
- 전화번호: 087165351281
-
Kunming, Yunnan, 중국, 650107
- 모병
- Yunnan Province Cancer Hospital ( Site 0418)
-
연락하다:
- Study Coordinator
- 전화번호: 0871-68179210
-
-
Zhejiang
-
Hangzhou, Zhejiang, 중국, 310014
- 모병
- Zhejiang Provincial People's Hospital-Urology ( Site 0378)
-
연락하다:
- Study Coordinator
- 전화번호: +86 13858019285
-
Hangzhou, Zhejiang, 중국, 310022
- 모병
- Zhejiang Cancer Hospital ( Site 0435)
-
연락하다:
- Study Coordinator
- 전화번호: 0571-88122261
-
Jiaxing, Zhejiang, 중국, 314001
- 모병
- The First Hospital of Jiaxing-urology ( Site 0380)
-
연락하다:
- Study Coordinator
- 전화번호: +86 13957391616
-
Ningbo, Zhejiang, 중국, 315010
- 모병
- The First Affiliated Hospital of Ningbo University ( Site 0383)
-
연락하다:
- Study Coordinator
- 전화번호: 86057487085588
-
Wenzhou, Zhejiang, 중국, 325000
- 모병
- The First Affiliated Hospital of Wenzhou Medical University-Urology Surgery ( Site 0379)
-
연락하다:
- Study Coordinator
- 전화번호: +8618267857001
-
-
-
-
-
Prague, 체코, 150 06
- 모집하지 않고 적극적으로
- Fakultní nemocnice Motol a Homolka ( Site 0551)
-
-
Brno-mesto
-
Brno, Brno-mesto, 체코, 656 53
- 모병
- Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0553)
-
연락하다:
- Study Coordinator
- 전화번호: +420 543 136 216
-
-
Moravian-Silesian Region
-
Ostrava, Moravian-Silesian Region, 체코, 708 52
- 모병
- Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 0554)
-
연락하다:
- Study Coordinator
- 전화번호: +420597372264
-
-
Olomouc Region
-
Olomouc, Olomouc Region, 체코, 779 00
- 모병
- Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 0555)
-
연락하다:
- Study Coordinator
- 전화번호: +420 588 444 699
-
-
-
-
-
Antofagasta, 칠레, 1240000
- 모병
- Bradford Hill Norte ( Site 0357)
-
연락하다:
- Study Coordinator
- 전화번호: 56442023631
-
-
Coquimbo Region
-
La Serena, Coquimbo Region, 칠레, 1720430
- 완전한
- IC La Serena Research ( Site 0356)
-
-
Los Ríos Region
-
Valdivia, Los Ríos Region, 칠레, 5110683
- 모집하지 않고 적극적으로
- Clinical Research Chile SpA ( Site 0358)
-
-
Maule Region
-
Talca, Maule Region, 칠레, 3465584
- 모병
- Clinica Universidad Catolica del Maule-Oncology ( Site 0355)
-
연락하다:
- Study Coordinator
- 전화번호: +56947532700
-
-
Region M. de Santiago
-
Santiago, Region M. de Santiago, 칠레, 8330024
- 모병
- Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0354)
-
연락하다:
- Study Coordinator
- 전화번호: +56934331806
-
Santiago, Region M. de Santiago, 칠레, 8420383
- 모병
- Bradfordhill-Clinical Area ( Site 0351)
-
연락하다:
- Study Coordinator
- 전화번호: +56229490970
-
Santiago, Region M. de Santiago, 칠레, 7500921
- 모집하지 않고 적극적으로
- Fundación Arturo López Pérez ( Site 0353)
-
-
-
-
Alberta
-
Edmonton, Alberta, 캐나다, T6G 1Z2
- 모병
- Cross Cancer Institute ( Site 0332)
-
연락하다:
- Study Coordinator
- 전화번호: 7804328762
-
-
Ontario
-
Ottawa, Ontario, 캐나다, K1H 8L6
- 모병
- The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre ( Site 0336)
-
연락하다:
- Study Coordinator
- 전화번호: 613-737-7700
-
Toronto, Ontario, 캐나다, M4N 3M5
- 모병
- Sunnybrook Research Institute ( Site 0331)
-
연락하다:
- Study Coordinator
- 전화번호: 647-533-1023
-
Toronto, Ontario, 캐나다, M5G 2M9
- 모병
- Princess Margaret Cancer Centre ( Site 0330)
-
연락하다:
- Study Coordinator
- 전화번호: (416) 946-4501
-
-
Quebec
-
Greenfield Park, Quebec, 캐나다, J4V 2H1
- 모병
- Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre ( Site 0328)
-
연락하다:
- Study Coordinator
- 전화번호: 4504665000 ext 3226
-
Montreal, Quebec, 캐나다, H2X 3E4
- 모집하지 않고 적극적으로
- Centre Hospitalier de l'Université de Montréal ( Site 0326)
-
Québec, Quebec, 캐나다, G1J 1Z4
- 모병
- Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0327)
-
연락하다:
- Study Coordinator
- 전화번호: 418 525-4444
-
Sherbrooke, Quebec, 캐나다, J1H 5H4
- 모집하지 않고 적극적으로
- Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 0329)
-
-
-
-
Bogota D.C.
-
Bogotá, Bogota D.C., 콜롬비아, 111321
- 모병
- Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 0501)
-
연락하다:
- Study Coordinator
- 전화번호: 6017058333
-
-
Cesar Department
-
Valledupar, Cesar Department, 콜롬비아, 200001
- 모병
- Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0502)
-
연락하다:
- Study Coordinator
- 전화번호: +57 3158505190
-
-
Departamento de Córdoba
-
Montería, Departamento de Córdoba, 콜롬비아, 230002
- 모병
- IMAT S.A.S ( Site 0504)
-
연락하다:
- Study Coordinator
- 전화번호: +573135342052
-
-
Santander Department
-
Piedecuesta, Santander Department, 콜롬비아, 681017
- 모병
- Fundación Cardiovascular de Colombia ( Site 0503)
-
연락하다:
- Study Coordinator
- 전화번호: +573203400438
-
-
Valle del Cauca Department
-
Cali, Valle del Cauca Department, 콜롬비아, 760032
- 모병
- Fundación Valle del Lili ( Site 0505)
-
연락하다:
- Study Coordinator
- 전화번호: +573133288646
-
Cali, Valle del Cauca Department, 콜롬비아, 760042
- 완전한
- Clínica Imbanaco S.A.S ( Site 0509)
-
-
-
-
Bangkok
-
Bangkok, Bangkok, 태국, 10330
- 모병
- Chulalongkorn University ( Site 1530)
-
연락하다:
- Study Coordinator
- 전화번호: +6622564533
-
Bangkoknoi, Bangkok, 태국, 10700
- 모병
- Faculty of Medicine Siriraj Hospital ( Site 1531)
-
연락하다:
- Study Coordinator
- 전화번호: +6624194489
-
-
Changwat Khon Kaen
-
Muang, Changwat Khon Kaen, 태국, 40002
- 모병
- Faculty of Medicine - Khon Kaen University ( Site 1526)
-
연락하다:
- Study Coordinator
- 전화번호: +66 43 366568-9
-
-
Changwat Songkhla
-
Hat Yai, Changwat Songkhla, 태국, 90110
- 모병
- Songklanagarind hospital ( Site 1527)
-
연락하다:
- Study Coordinator
- 전화번호: +6674451469
-
-
-
-
-
Adana, 터키 (Türkiye), 01250
- 모병
- Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1554)
-
연락하다:
- Study Coordinator
- 전화번호: +903223444444
-
Ankara, 터키 (Türkiye), 06010
- 모병
- Gulhane Egitim Arastirma Hastanesi ( Site 1558)
-
연락하다:
- Study Coordinator
- 전화번호: 00903123042020
-
Ankara, 터키 (Türkiye), 06230
- 모병
- Hacettepe Universite Hastaneleri-oncology hospital ( Site 1551)
-
연락하다:
- Study Coordinator
- 전화번호: +90 (312) 305 29 41
-
Ankara, 터키 (Türkiye), 06520
- 모병
- Memorial Ankara Hastanesi-Medical Oncology ( Site 1557)
-
연락하다:
- Study Coordinator
- 전화번호: 903122536666
-
Ankara, 터키 (Türkiye), 06800
- 모병
- Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1552)
-
연락하다:
- Study Coordinator
- 전화번호: 00903125526060
-
Istanbul, 터키 (Türkiye), 34668
- 모병
- Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1555)
-
연락하다:
- Study Coordinator
- 전화번호: 0090212 414 30 00
-
Istanbul, 터키 (Türkiye), 34722
- 모병
- TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1553)
-
연락하다:
- Study Coordinator
- 전화번호: +902166065200
-
Istanbul, 터키 (Türkiye), 34010
- 모병
- Koc Universitesi Hastanesi ( Site 1561)
-
연락하다:
- Study Coordinator
- 전화번호: +908502508250
-
Samsun, 터키 (Türkiye), 55200
- 모병
- Samsun Medical Park Hastanesi-medical oncology ( Site 1560)
-
연락하다:
- Study Coordinator
- 전화번호: +90 (539) 780 90 07
-
-
-
-
-
Lima, 페루, 15038
- 모병
- INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS-Medical Oncology ( Site 1256)
-
연락하다:
- Study Coordinator
- 전화번호: +511 2016500
-
Lima, 페루, 15036
- 모집하지 않고 적극적으로
- Aliada-Oncologìa ( Site 1257)
-
Lima, 페루, 15036
- 모집하지 않고 적극적으로
- IPOR Instituto Peruano de Oncología & Radioterapia-Centro de Investigación ( Site 1254)
-
Lima, 페루, 15036
- 모집하지 않고 적극적으로
- Oncosalud-Clinical Research ( Site 1260)
-
-
Departamento de Junín
-
Concepción, Departamento de Junín, 페루, 12125
- 모병
- Instituto Regional de Enfermedades Neoplasicas del Centro (IREN CENTRO) ( Site 1258)
-
연락하다:
- Study Coordinator
- 전화번호: +51 958864658
-
-
La Libertad
-
Trujillo, La Libertad, 페루, 13009
- 모병
- Clínica Sánchez Ferrer ( Site 1261)
-
연락하다:
- Study Coordinator
- 전화번호: 948319999
-
-
-
-
Kuyavian-Pomeranian Voivodeship
-
Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 폴란드, 85-796
- 모집하지 않고 적극적으로
- Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1302)
-
Grudziądz, Kuyavian-Pomeranian Voivodeship, 폴란드, 86-300
- 완전한
- Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 1316)
-
Torun, Kuyavian-Pomeranian Voivodeship, 폴란드, 87-100
- 완전한
- Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 1304)
-
-
Masovian Voivodeship
-
Siedlce, Masovian Voivodeship, 폴란드, 08-110
- 모병
- Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1310)
-
연락하다:
- Study Coordinator
- 전화번호: +48256403301
-
-
West Pomeranian Voivodeship
-
Koszalin, West Pomeranian Voivodeship, 폴란드, 75-581
- 모병
- Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1303)
-
연락하다:
- Study Coordinator
- 전화번호: +48943488930
-
Szczecin, West Pomeranian Voivodeship, 폴란드, 71-730
- 모병
- Zachodniopomorskie Centrum Onkologii ( Site 1311)
-
연락하다:
- Study Coordinator
- 전화번호: +48914251502
-
-
Świętokrzyskie Voivodeship
-
Kielce, Świętokrzyskie Voivodeship, 폴란드, 25-734
- 모병
- Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch ( Site 1318)
-
연락하다:
- Study Coordinator
- 전화번호: +48413674811
-
-
-
-
-
Hato Rey, 푸에르토 리코, 00917
- 완전한
- Puerto Rico Medical Research Center LLC ( Site 1354)
-
Ponce, 푸에르토 리코, 00717
- 모집하지 않고 적극적으로
- Ad-Vance Medical Research-Research ( Site 1353)
-
San Juan, 푸에르토 리코, 00909
- 완전한
- Pan American Center for Oncology Trials - Ciudadela ( Site 1351)
-
-
-
-
-
Paris, 프랑스, 75015
- 모집하지 않고 적극적으로
- Hôpital Européen Georges Pompidou ( Site 0628)
-
-
Ain
-
Lille, Ain, 프랑스, 59020
- 모병
- Centre Oscar Lambret ( Site 0634)
-
연락하다:
- Study Coordinator
- 전화번호: +33320295959
-
-
Bas-Rhin
-
Strasbourg, Bas-Rhin, 프랑스, 67200
- 모병
- Hopitaux Universitaires de Strasbourg ( Site 0627)
-
연락하다:
- Study Coordinator
- 전화번호: +33368767207
-
-
Gard
-
Nîmes, Gard, 프랑스, 30029
- 모병
- Centre Hospitalier Universitaire de Nîmes - Institut de Cancérologie du Gard - Hôpital Universitaire ( Site 0630)
-
연락하다:
- Study Coordinator
- 전화번호: +33466683301
-
-
Ille-et-Vilaine
-
Rennes, Ille-et-Vilaine, 프랑스, 35042
- 모병
- Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 0632)
-
연락하다:
- Study Coordinator
- 전화번호: +33299253182
-
-
Puy-de-Dome
-
Clermont-Ferrand, Puy-de-Dome, 프랑스, 63003
- 모병
- Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne ( Site 0629)
-
연락하다:
- Study Coordinator
- 전화번호: +33473278005
-
-
Pyrenees-Atlantiques
-
Bayonne, Pyrenees-Atlantiques, 프랑스, 64109
- 모병
- Centre Hospitalier de la Cote Basque ( Site 0633)
-
연락하다:
- Study Coordinator
- 전화번호: 33559443535
-
-
Val-de-Marne
-
Villejuif, Val-de-Marne, 프랑스, 94800
- 모병
- Gustave Roussy ( Site 0626)
-
연락하다:
- Study Coordinator
- 전화번호: +33 1 42 11 42 11
-
-
-
-
Northern Savonia
-
Kuopio, Northern Savonia, 핀란드, 70200
- 모집하지 않고 적극적으로
- Kuopion Yliopistollinen Sairaala ( Site 0603)
-
-
Pirkanmaa
-
Tampere, Pirkanmaa, 핀란드, 33520
- 모병
- Tampereen yliopistollinen sairaala ( Site 0604)
-
연락하다:
- Study Coordinator
- 전화번호: 358331166811
-
-
Southwest Finland
-
Turku, Southwest Finland, 핀란드, 20520
- 모병
- Turku University Hospital-Department of Oncology ( Site 0601)
-
연락하다:
- Study Coordinator
- 전화번호: 35823130729
-
-
-
-
-
Debrecen, 헝가리, 4032
- 모병
- Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 0758)
-
연락하다:
- Study Coordinator
- 전화번호: +3652411717
-
-
Bács-Kiskun county
-
Kecskemét, Bács-Kiskun county, 헝가리, 6000
- 모병
- Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 0752)
-
연락하다:
- Study Coordinator
- 전화번호: +3676516719
-
-
Nógrád megye
-
Salgótarján, Nógrád megye, 헝가리, 3100
- 모병
- Nograd Varmegyei Szent Lazar Korhaz-Onkologia es Sugarterapias Osztaly ( Site 0761)
-
연락하다:
- Study Coordinator
- 전화번호: +3632522000
-
-
Pest County
-
Budapest, Pest County, 헝가리, 1122
- 모병
- Országos Onkológiai Intézet-Urogenitális Tumorok és Klinikai Farmakológiai Osztály ( Site 0756)
-
연락하다:
- Study Coordinator
- 전화번호: +36122486001171
-
-
-
-
New South Wales
-
Dubbo, New South Wales, 호주, 2830
- 모병
- Dubbo Hospital ( Site 0235)
-
연락하다:
- Study Coordinator
- 전화번호: 0268096200
-
Macquarie University, New South Wales, 호주, 2109
- 모병
- Macquarie University-MQ Health Clinical Trials Unit ( Site 0234)
-
연락하다:
- Study Coordinator
- 전화번호: 0298122979
-
Westmead, New South Wales, 호주, 2145
- 모병
- Westmead Hospital ( Site 0232)
-
연락하다:
- Study Coordinator
- 전화번호: +61288905555
-
-
Queensland
-
Brisbane, Queensland, 호주, 4102
- 모병
- Princess Alexandra Hospital-Cancer Care Serices ( Site 0237)
-
연락하다:
- Study Coordinator
- 전화번호: +6173176 9289
-
-
Victoria
-
Melbourne, Victoria, 호주, 3000
- 모병
- Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0230)
-
연락하다:
- Study Coordinator
- 전화번호: 03 8559 5000
-
-
-
-
-
Hong Kong, 홍콩
- 모집하지 않고 적극적으로
- Queen Mary Hospital ( Site 0727)
-
Shatin, 홍콩
- 모집하지 않고 적극적으로
- Prince of Wales Hospital ( Site 0730)
-
-
참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
18년 이상 (성인, 고령자)
건강한 자원 봉사자를 받아들입니다
아니
연구 대상 성별
모두
설명
Inclusion Criteria:
- Has histologically- or cytologically-confirmed adenocarcinoma of the prostate without small cell histology.
- Has prostate cancer progression while on androgen deprivation therapy (or post bilateral orchiectomy) within 6 months before Screening
- Has current evidence of distant metastatic disease (M1 disease) documented by either bone lesions on bone scan and/or soft tissue disease by computed tomography/magnetic resonance imaging (CT/MRI).
- Has disease that progressed during or after treatment with 1 novel hormonal agent (NHA)
- Has received 1 but no more than 2 taxane-based chemotherapy regimens for metastatic castration-resistant prostate cancer (mCRPC) and has had progressive disease (PD) during or after treatment
- Has ongoing androgen deprivation with serum testosterone <50 ng/dL (<1.7 nM)
- Has provided tumor tissue from a fresh core or excisional biopsy from soft tissue not previously irradiated
- Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 assessed within 7 days of randomization
- Has had prior treatment with PARPi or were deemed ineligible to receive treatment by the investigator or have refused PARPi treatment
- Has received prior 177Lu-PSMA-617 or were deemed ineligible to receive 177Lu-PSMA-617 treatment by the investigator or refused 177Lu-PSMA-617 treatment
- Participants who have not received cabazitaxel can be enrolled if they are ineligible for cabazitaxel treatment as determined by the investigator or have refused treatment
- If participant received first generation anti-androgen therapy before screening, the participant has evidence of disease progression >4 weeks since the last flutamide treatment and >6 weeks since the last bicalutamide or nilutamide treatment
- Participants receiving bone resorptive therapy (including, but not limited to, bisphosphonate or denosumab) must have been on stable doses for ≥ 4 weeks before the date of randomization
- Participants with human immunodeficiency virus (HIV) infection must have well controlled HIV on antiretroviral therapy (ART)
- Participants who are hepatitis B surface antigen (HBsAg) positive are eligible if they have received hepatitis B virus (HBV) antiviral therapy for at least 4 weeks and have undetectable HBV viral load before randomization
- Participants with history of hepatitis C virus (HCV) infection are eligible if HCV viral load is undetectable at Screening.
- Participants who can produce sperm must agree to the following during the study treatment period and for at least 7 days after the last dose of opevesostat, for at least 30 days after the last dose of abiraterone acetate, and for at least 3 months after the last dose of enzalutamide: EITHER be abstinent OR must agree to use male condom
Exclusion Criteria:
- Has a gastrointestinal disorder that might affect absorption
- Has a history of pituitary dysfunction
- Has poorly controlled diabetes mellitus
- Has clinically significant abnormal serum potassium or sodium level
- Has a history of active or unstable cardio/cerebro-vascular disease, including thromboembolic events
- Has a history of seizure within 6 months of providing documented informed consent or any condition that may predispose to seizures within 12 months before the date of randomization
- Has a history of clinically significant ventricular arrhythmias
- Has received an anticancer monoclonal antibody (mAb) within 4 weeks before the date of randomization, or has not recovered from adverse events (AEs) due to mAbs administered more than 4 weeks before the date of randomization
- Has undergone major surgery, including local prostate intervention (except prostate biopsy), within 28 days before the date of randomization, and has not recovered from the toxicities and/or complications
- Participants who have not adequately recovered from major surgery or have ongoing surgical complications
- Has used herbal or medicinal products that may have hormonal anti-prostate cancer activity and/or are known to decrease prostate-specific Antigen (PSA) (eg, saw palmetto, megesterol acetate, citrus pectin polysaccharide) within 4 weeks before the date of randomization
- Has received radium-223 or Lutetium-177 within 4 weeks before the date of randomization, or has not recovered to Grade ≤1 or baseline from AEs due to radium-223 or Lutetium-177 administered more than 4 weeks before the date of randomization
- Has received treatment with 5-αreductase inhibitors (eg, finasteride or dutasteride), estrogens, or cyproterone within 4 weeks before the date of randomization
- Has received colony-stimulating factors within 28 days before the date of randomization
- Has received a whole blood transfusion in the last 120 days before the date of randomization. Packed red blood cells and platelet transfusions are acceptable if not given within 28 days of the date of randomization
- Has received prior targeted small molecule therapy or NHA treatment within 4 weeks before the first dose of study intervention as follows: enzalutamide or apalutamide within 3 weeks or abiraterone acetate + prednisone or darolutamide within 2 weeks
- Has a "superscan" bone scan
- Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy or any other form of immunosuppressive therapy within 7 days prior the first dose of study medication
- Has a known additional malignancy that is progressing or has required active treatment within the past 3 years
- Has known active central nervous system (CNS) metastases and/or carcinomatous meningitis
- Has an active autoimmune disease that has required systemic treatment in past 2 years
- Has an active infection requiring systemic therapy
- Has concurrent active HBV or known active HCV infection
- Has a history of long QTc syndrome
- Has any of the following at Screening Visit: hypotension (systolic BP <110 mm Hg) or uncontrolled hypertension (systolic BP ≥160 mm Hg or diastolic BP ≥90 mm Hg, in 2 out of 3 recordings with optimized antihypertensive therapy)
- Is unable to swallow capsules/tablets
- Is currently being treated with cytochrome 450-inducing antiepileptic drugs for seizures
- Participants on an unstable dose of thyroid hormone therapy within 6 months before the start of the study intervention
- Received prior systemic anticancer therapy including investigational agents within 4 weeks before the first dose of study intervention
- Received prior radiotherapy within 2 weeks of start of study intervention, or radiation-related toxicities, requiring corticosteroids
- Received a live or live-attenuated vaccine within 30 days before the first dose of study intervention
- Systemic use of the following medications within 2 weeks before the first dose of study intervention: strong CYP3A4 inducers (eg, avasimibe, carbamazepine, lumacaftor, phenobarbital, rifampicin, rifapentine, or St John's Wort); P-gp inhibitors (eg, erythromycin, clarithromycin, rifampicin, ketoconazole, itraconazole, posaconazole, artesunate-pyronaridine, ritonavir, indinavir, nelfinavir, atazanavir, glecaprevir-pibrentasvir, simeprevir, ledipasvir-sofosbuvir, verapamil, diltiazem, dronedarone, propafenone, quinidine, cyclosporine, valspodar, or milk thistle [Silybum marianum])
- Use of aldosterone antagonist (eg, spironolactone, eplerenone) and phenytoin within 4 weeks before the start of the study intervention
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
|
실험적: Opevesostat
Participants receive opevesostat 5 mg by oral tablets twice daily (bid) plus dexamethasone 1.5 mg by oral tablets once daily (qd) and 0.1 mg fludrocortisone acetate by oral tablet qd until progression. Hydrocortisone 100 mg (oral or intramuscular [IM]) dose will also be provided to participants for use as rescue medication. Prior to study protocol amendment 9, prednisone was provided as a rescue medication during adrenal recovery, titrated at 5mg daily maintenance dose and then titrated to discontinuation. |
Administered orally
다른 이름들:
Administered orally or IM as a rescue medication Administered orally Administered orally as a rescue medication Administered orally as rescue medication |
|
활성 비교기: Abiraterone Acetate or Enzalutamide
Participants receive abiraterone 1000 mg qd by oral tablets plus prednisone 5 mg bid by oral tablets or enzalutamide 160 mg qd by oral tablets. |
Administered orally as a rescue medication Administered orally
다른 이름들:
Administered orally
다른 이름들:
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Overall Survival (OS) in Androgen Receptor Ligand Binding Domain (AR LBD) Mutation-Positive Participants
기간: Up to ~54 months
|
OS is defined as time from randomization to death due to any cause. OS in AR LBD mutation-positive participants will be reported for each study arm. |
Up to ~54 months
|
|
OS in AR LBD Mutation-Negative Participants
기간: Up to ~54 months
|
OS is defined as time from randomization to death due to any cause. OS in AR LBD mutation-negative participants will be reported for each study arm. |
Up to ~54 months
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Radiographic Progression-free Survival (rPFS) Per Prostate Cancer Working Group-modified Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as Assessed by Blinded Independent Central Review in AR LBD Mutation-Positive Participants
기간: Up to ~36 months
|
rPFS is defined as the time from randomization to the first documented disease progression per Prostate Cancer Working Group (PCWG)-modified Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as assessed by Blinded Independent Central Review (BICR) or death due to any cause, whichever occurs first. rPFS in AR LBD mutation-positive participants will be reported for each study arm. |
Up to ~36 months
|
|
rPFS Per Prostate Cancer Working Group-modifiedRECIST 1.1 as Assessed by Blinded Independent Central Review in AR LBD Mutation-Negative Participants
기간: Up to ~36 months
|
rPFS is defined as the time from randomization to the first documented disease progression per Prostate Cancer Working Group (PCWG)-modified Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as assessed by Blinded Independent Central Review (BICR) or death due to any cause, whichever occurs first. rPFS in AR LBD mutation-positive participants will be reported for each study arm. |
Up to ~36 months
|
|
Time to Initiation of the First Subsequent Anti-Cancer Therapy or Death (TFST)
기간: Up to ~54 months
|
TFST is defined as the time from randomization to initiation of the first subsequent anticancer therapy or death, whichever occurs first. |
Up to ~54 months
|
|
Objective Response (OR)
기간: Up to ~54 months
|
OR is determined by PCWG-modified RECIST 1.1 as assessed by BICR. |
Up to ~54 months
|
|
Duration of Response (DOR)
기간: Up to ~54 months
|
DOR is determined by PCWG-modified RECIST 1.1 as assessed by BICR. |
Up to ~54 months
|
|
Time to Pain Progression (TTPP)
기간: Up to ~54 months
|
TTPP is assessed by Brief Pain Inventory-Short Form (BPI-SF) Item 3 ("Worst Pain in 24 Hours") and opiate analgesic use (Analgesic Quantification Algorithm [AQA] Score). |
Up to ~54 months
|
|
Time to Prostate-specific Antigen (PSA) Progression
기간: Up to ~54 months
|
The time from randomization to PSA progression. The PSA progression date is defined as the date of either: 1) ≥25% increase and ≥2 ng/mL above the nadir, confirmed by a second value ≥3 weeks later if there is PSA decline from baseline 2) ≥25% increase and ≥2 ng/mL increase from baseline beyond 12 weeks if there is no PSA decline from baseline. |
Up to ~54 months
|
|
Time to First Symptomatic Skeletal-related Event (SSRE)
기간: Up to ~54 months
|
The time from randomization to the first occurrence of any of the following symptomatic skeletal-related events: 1) Use of EBRT to prevent or relieve skeletal symptoms; 2) new symptomatic pathologic bone fracture (vertebral or non-vertebral); 3) spinal cord compression; or 4) tumor-related orthopedic surgical intervention. |
Up to ~54 months
|
|
Number of Participants Who Experience an Adverse Event
기간: Up to ~54 months
|
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. |
Up to ~54 months
|
|
Number of Participants Who Discontinue Study Treatment Due to an Adverse Event
기간: Up to ~54 months
|
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. |
Up to ~54 months
|
공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
수사관
- 연구 책임자: Medical Director, Merck Sharp & Dohme LLC
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (실제)
2023년 12월 31일
기본 완료 (추정된)
2028년 11월 30일
연구 완료 (추정된)
2030년 3월 29일
연구 등록 날짜
최초 제출
2023년 11월 13일
QC 기준을 충족하는 최초 제출
2023년 11월 13일
처음 게시됨 (실제)
2023년 11월 18일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2026년 11월 5일
QC 기준을 충족하는 마지막 업데이트 제출
2026년 11월 4일
마지막으로 확인됨
2026년 11월 1일
추가 정보
이 연구와 관련된 용어
추가 관련 MeSH 약관
기타 연구 ID 번호
- 5684-003
- MK-5684-003 (기타 식별자: MSD)
- jRCT2031240029 (레지스트리 식별자: Japan Registry of Clinical Trials (jRCT))
- U1111-1287-5304 (레지스트리 식별자: UTN)
- 2023-504899-25-00 (기타 식별자: EU CT)
- 2023 (미국 NIH 보조금/계약)
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
예
IPD 계획 설명
https://trialstransparency.msdclinicaltrials.com/pdf/ProcedureAccessClinicalTrialData.pdf
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
예
미국 FDA 규제 기기 제품 연구
아니
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .