Clinical trial of Fecal Microbiota Transplantation in Postoperative Crohn's Disease

The company Tampere University Hospital is enrolling patients into the clinical trial investigating Fecal Microbiota Transplantation in Postoperative Crohn's Disease.

This pilot study aims to detect possible trends or signals suggesting efficacy of FMT on prevention of delay of POR, to determine the safety of FMT in post operative CD, and asses if a full randomised controlled trial is feasible in this setting. With microbiota analysis we aim to assess if changes in gut microbiota are related to disease course of CD after operation.

The trial is designed to enroll male and female 18 Years to 120 Years and is being conducted in the Tampere University Hospital.

The study start date is November 2020.

The patients that can be enrolled into this study include:

  • Over 18 years - Able to provide written consent - Stricturing and/or fistulizing Crohn's disease needing ileocecal or ileal resection Exclusion Criteria: - Pregnancy - Active infection, abscess or fistula at the time of the first colonoscopy - Life expectancy <1 year - Unable to provide written consent - Use on antibiotics or probiotics at the time of first colonoscopy.

The population that are excluded from participation:

  • Pregnancy - Active infection, abscess or fistula at the time of the first colonoscopy - Life expectancy <1 year - Unable to provide written consent - Use on antibiotics or probiotics at the time of first colonoscopy.

This page provides a more detailed overview of this clinical trial:

https://ichgcp.net/clinical-trials-registry/NCT04637438

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