Epidural steroid injections for lumbar spinal stenosis

Mark A Harrast, Mark A Harrast

Abstract

Degenerative lumbar stenosis is a common source of pain and disability in the elderly. It presents clinically with a variety of symptoms, though neurogenic claudication is the hallmark. There is a multifactorial pathogenesis to lumbar stenosis and its symptoms, and thus, there are multiple management approaches available. Epidural steroid injections (ESIs) are a popular choice in management, however, the literature is vague in definitive support of their use, and providers that utilize injections can use variable techniques to access the spinal canal in order to deposit the steroid at the appropriate site. This article will review degenerative lumbar stenosis in general and focus on the use of ESIs to better define their role in this management process. In addition, the evidence to discern the optimal injection route will be presented.

Figures

Fig. 1
Fig. 1
An 64-year-old female with symptoms of bilateral lower limb neurogenic claudication with symptomatic improvement with a caudal epidural steroid injection. An interlaminar approach could have been considered appropriate, as well. (a) Sagittal view of a T2-weighted MRI of the lumbar spine. Note the grade I spondylolisthesis of L4 on L5 with severe central canal stenosis. (b) and (c) Axial views of a T2-weighted MRI through L4–5. Note the diffuse disc bulge in (b) and the marked ligamentum flavum hypertophy in (c), both contributing to the severe central stenosis. (d) The L5-S1 level showing no evidence of stenosis
Fig. 2
Fig. 2
An 84-year-old male with low back pain and right L4 radicular symptoms to the ankle worsened with walking with symptomatic improvement with a right L4-5 transforaminal epidural steroid injection. (a) Right sagittal view of a T2-weighted MRI of the lumbar spine. Note the multilevel degenerative changes and the foraminal stenosis at L4-5 related to disc bulge and facet hypertrophy. (b) Axial view of a T2-weighted MRI through L4-5. Note severe central stenosis on imaging, though symptomatically, he described right L4 radicular symptoms and thus a transforaminal route was chosen
Fig. 3
Fig. 3
Fluoroscopic images of an L3-4 interlaminar approach. (a) AP view, pre-contrast, (b) Lateral view, pre-contrast, and (c) Lateral view, post-contrast
Fig. 4
Fig. 4
Fluoroscopic images of a caudal approach. (a) Lateral view, pre-contrast and (b) lateral view, post-contrast
Fig. 5
Fig. 5
Fluoroscopic images of a right L5-S1 transforaminal approach targeting the right L5 nerve root. (a) AP view, pre-contrast and (b) AP view, post-contrast

References

    1. Kirkaldy-Willis WH, Wedge JH, Yong-Hing K, et al. Pathology and pathogenesis of lumbar spondylosis and stenosis. Spine. 1978;3:319–28. doi: 10.1097/00007632-197812000-00004.
    1. Atlas SJ, Deyo RA, Keller RB, et al. The Maine lumbar spine study, Part III: 1-Year outcomes of surgical and nonsurgical management of lumbar spinal stenosis. Spine. 1996;21:1787–94. doi: 10.1097/00007632-199608010-00012.
    1. Johnsson KE, Rosen I, Uden A. The natural course of lumbar spinal stenosis. Clin Orthop 1992;Jun:82–6
    1. Simotas AC, Dorey FJ, Hansraj KK, et al. Nonoperative treatment for lumbar spinal stenosis: clinical and outcome Results and a 3-year survivorship analysis. Spine. 2000;25:197–204. doi: 10.1097/00007632-200001150-00009.
    1. Swezey RL. Outcomes for lumbar stenosis: a 5-year follow-up study. J Cir Rheumatol. 1996;2:129–34. doi: 10.1097/00124743-199606000-00004.
    1. Atlas SJ, Keller RB, Wu YA, et al. Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the Maine lumbar spine study. Spine. 2005;30:936–43. doi: 10.1097/01.brs.0000158953.57966.c0.
    1. Crock HV. The applied anatomy of spinal circulation in spinal stenosis. In: McNeill TW, editor. Lumbar spinal stenosis. St. Louis: Mosby; 1992.
    1. Ooi Y, MIta F, Satoh Y. Myeloscopic study on lumbar spinal canal stenosis with special reference to intermittent claudication. Spine. 1990;15:544–9. doi: 10.1097/00007632-199006000-00021.
    1. Akuthota V, Lento P, Sowa G. Pathogenesis of lumbar spinal stenosis pain: why does an asymptomatic stenotic patient flare? Phys Med Rehabil Clin N Am. 2003;14:17–28.
    1. Goupille P, Jayson MI, Valat JP, et al. The role of inflammation in disk herniation-associated radiculopathy. Semin Arthritis Rheum. 1998;28:60–7. doi: 10.1016/S0049-0172(98)80029-2.
    1. Airaksinen O, Herno A, Turunen V, et al. Surgical outcome of 438 patients treated surgically for lumbar spinal stenosis. Spine. 1997;22:2278–82. doi: 10.1097/00007632-199710010-00016.
    1. Botwin KP, Gruber RD. Lumbar epidural steroid injections in the patient with lumbar stenosis. Phys Med Rehabil Clin N Am. 2003;14:121–41.
    1. Johansson A, Hao J, Sjolund B. Local corticosteroid application blocks transmission in normal nociceptive C-fibers. Acta Anesthesiol Scand. 1990;34:335–58.
    1. Olmarker K, Byrod G, Cornefjord M, et al. Effects of Methylprednisolone on nucleus pulposus-induced nerve root injury. Spine. 1994;19:1803–8. doi: 10.1097/00007632-199408150-00003.
    1. Renfrew DL, Morre TE, Kathol MH, et al. Correct placement of epidural steroid injections: fluoroscopic guidance and contrast administration. Am J Neuroradiol. 1991;12:1003–7.
    1. Sitz M, Sommer HM. Accuracy of blind versus fluoroscepically guided caudal epidural injections. Spine. 1999;13:1371–6. doi: 10.1097/00007632-199907010-00016.
    1. Ciocon JO, Galindo-Ciocon D, Amaranath L, et al. Caudal epidural blocks for elderly patients with lumbar canal stenosis. J Am Geriatric Soc. 1994;42:593–6.
    1. Fukusaki M, Kobayashi I, Hara T, et al. Symptoms of spinal stenosis do not improve after epidural steroid injection. Clin J Pain. 1998;14:148–51. doi: 10.1097/00002508-199806000-00010.
    1. Hoogmartens M, Morelle P. Epidural injections in the treatment of spinal stenosis. Acta Orthop Belg. 1987;53:409–11.
    1. Rosen CD, Kahanovitz N, Bernstein R, et al. A retrospective analysis of the efficacy of epidural steroid injections. Clin Orthop. 1988;228:270–2.
    1. Barre’ L, Lutz GE, Southern D, et al. Fluoroscopically guided caudal epidural steroid injections for lumbar stenosis: a retropective evaluation of long term efficacy. Pain Physician. 2004;7:187–93.
    1. Botwin KP, Gruber RD, Bouchlas CG, et al. Fluoroscopically guided lumbar transformational epidural steroid injections in degenerative lumbar stenosis: an outcome study. Am J Phys Med Rehabil. 2002;81:898–905. doi: 10.1097/00002060-200212000-00003.
    1. Cooper G, Lutz GE, Boachie-Adjei O, et al. Effectiveness of transforaminal epidural steroid injections in patients with degenerative lumbar scoliotic stenosis and radiculopathy. Pain Physician. 2004;7:311–7.
    1. Delport EG, Cucuzella AR, Marley JK, et al. Treatment of lumbar spinal stenosis with epidural steroid injections: a retrospective outcome study. Arh Phys Med Rehabil. 2004;85:479–84. doi: 10.1016/S0003-9993(03)00472-6.
    1. Riew KD, Yin Y, Gilula L, et al. The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study. J Bone Joint Surg Am. 2000;82-A:1589–93.
    1. Schaufele M, Hatch L, Jones W. Interlaminar versus transforaminal epidural injections for the treatment of symptomatic lumbar intervertebral disc herniations. Pain Physician. 2006;9:361–6.
    1. Vad VB, Bhat AL, Lutz GE, et al. Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study. Spine. 2002;27:11–6. doi: 10.1097/00007632-200201010-00005.

Source: PubMed

3
Abonneren