International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons

Abstract

Osteosarcoma incidence rates in the United States peak in adolescence and in the elderly. The international patterns of osteosarcoma incidence in children have been described, whereas those for young, middle age or elderly adults have not. Using the Cancer Incidence in Five Continents, International Agency for Cancer Research database we compared incidence rates for children and adolescents (age 0-24 years), the middle age group (25-59 years) and elderly (>or=60 years) persons by world regions and individual countries. Overall, worldwide osteosarcoma incidence rates were quite similar in the younger age groups. The greatest variation in incidence rates was observed in the elderly.

Figures

Figure 1

Osteosarcoma incidence by country or region. Calendar period and the countries with national or regional registries are shown in Table 1. The world rates include data from all countries and registries listed in Table 1. Black triangles are male rates, grey circles are female rates; †, number of osteosarcoma cases were available for all ages in this region but rate data was not; *, 75–79 age group includes data from only East, West, and South European countries; §, 65–69 and 70–74 age groups do not include data from Asia, Latin America or North European countries.