COVID-19 Vaccination Hesitancy in the United States: A Rapid National Assessment

Jagdish Khubchandani, Sushil Sharma, James H Price, Michael J Wiblishauser, Manoj Sharma, Fern J Webb, Jagdish Khubchandani, Sushil Sharma, James H Price, Michael J Wiblishauser, Manoj Sharma, Fern J Webb

Abstract

Given the results from early trials, COVID-19 vaccines will be available by 2021. However, little is known about what Americans think of getting immunized with a COVID-19 vaccine. Thus, the purpose of this study was to conduct a comprehensive and systematic national assessment of COVID-19 vaccine hesitancy in a community-based sample of the American adult population. A multi-item valid and reliable questionnaire was deployed online via mTurk and social media sites to recruit U.S. adults from the general population. A total of 1878 individuals participated in the study where the majority were: females (52%), Whites (74%), non-Hispanic (81%), married (56%), employed full time (68%), and with a bachelor's degree or higher (77%). The likelihood of getting a COVID-19 immunization in the study population was: very likely (52%), somewhat likely (27%), not likely (15%), definitely not (7%), with individuals who had lower education, income, or perceived threat of getting infected being more likely to report that they were not likely/definitely not going to get COVID-19 vaccine (i.e., vaccine hesitancy). In unadjusted group comparisons, compared to their counterparts, vaccine hesitancy was higher among African-Americans (34%), Hispanics (29%), those who had children at home (25%), rural dwellers (29%), people in the northeastern U.S. (25%), and those who identified as Republicans (29%). In multiple regression analyses, vaccine hesitancy was predicted significantly by sex, education, employment, income, having children at home, political affiliation, and the perceived threat of getting infected with COVID-19 in the next 1 year. Given the high prevalence of COVID-19 vaccine hesitancy, evidence-based communication, mass media strategies, and policy measures will have to be implemented across the U.S. to convert vaccines into vaccinations and mass immunization with special attention to the groups identified in this study.

Keywords: COVID-19; Infection; Pandemic; Prevention; Public health; Vaccine.

Conflict of interest statement

Authors have no conflicts of interests to declare.

References

    1. Centers for Disease Control and Prevention. (2020). CDC COVID data tracker. Retrieved from .
    1. Cutler DM, Summers LH. The COVID-19 pandemic and the $16 trillion virus. JAMA. 2020;324(15):1495–1496. doi: 10.1001/jama.2020.19759.
    1. Cohen J. Vaccine wagers on coronavirus surface protein pay off. Science. 2020;370(6519):894–895. doi: 10.1126/science.370.6519.894.
    1. Branswell, H. (2020). The Covid-19 vaccines are a marvel of science. Here’s how we can make the best use of them. Retrieved from .
    1. Centers for Disease Control and Prevention. (2020). How CDC is making COVID-19 vaccine recommendations. Retrieved from .
    1. Ball P. Anti-vaccine movement could undermine efforts to end coronavirus pandemic, researchers warn. Nature. 2020;581(7808):251. doi: 10.1038/d41586-020-01423-4.
    1. Dror AA, Eisenbach N, Taiber S, Morozov NG, Mizrachi M, Zigron A, et al. Vaccine hesitancy: The next challenge in the fight against COVID-19. European Journal of Epidemiology. 2020;35(8):775–779. doi: 10.1007/s10654-020-00671-y.
    1. Badur S, Ota M, Öztürk S, Adegbola R, Dutta A. Vaccine confidence: The keys to restoring trust. Human Vaccines & Immunotherapeutics. 2020;16(5):1007–1017. doi: 10.1080/21645515.2020.1740559.
    1. National Academies of Sciences, Engineering, and Medicine. (2020). Framework for equitable allocation of COVID‐19 vaccine. Retrieved from .
    1. McAteer J, Yildirim I, Chahroudi A. The VACCINES Act: Deciphering vaccine hesitancy in the time of COVID-19. Clinical Infectious Diseases. 2020;71(15):703–705. doi: 10.1093/cid/ciaa433.
    1. World Health Organizations. (2019). Ten threats to global health in 2019. Retrieved from .
    1. Harrison EA, Wu JW. Vaccine confidence in the time of COVID-19. European Journal of Epidemiology. 2020;35(4):325–330. doi: 10.1007/s10654-020-00634-3.
    1. Khubchandani J, Price JH. Public perspectives on firearm sales in the United States during the COVID-19 pandemic. Journal of the American College of Emergency Physicians Open. 2020 doi: 10.1002/emp2.12293.
    1. Price JH, Dake JA, Murnan J, Dimmig J, Akpanudo S. Power analysis in survey research: Importance and use for health educators. American Journal of Health Education. 2005;36(4):202–209. doi: 10.1080/19325037.2005.10608185.
    1. Lazarus JV, Ratzan SC, Palayew A, Gostin LO, Larson HJ, Rabin K, et al. A global survey of potential acceptance of a COVID-19 vaccine. Nature Medicine. 2020 doi: 10.1038/s41591-020-1124-9.
    1. Fisher KA, Bloomstone SJ, Walder J, Crawford S, Fouayzi H, Mazor KM. Attitudes toward a potential SARS-CoV-2 vaccine: A survey of US adults. Annals of Internal Medicine. 2020 doi: 10.7326/M20-3569.
    1. Callaghan T, Moghtaderi A, Lueck JA, Hotez PJ, Strych U, Dor A, et al. Correlates and disparities of COVID-19 vaccine hesitancy. Available at SSRN 3667971. 2020 doi: 10.2139/ssrn.3667971.
    1. Kaiser Family Foundation. (2020). Poll: Most Americans worry political pressure will lead to premature approval of a COVID-19 vaccine; half say they would not get a free vaccine approved before election day. Retrieved from .
    1. Webb FJ, Khubchandani J, Striley CW, Cottler LB. Black–white differences in willingness to participate and perceptions about health research: Results from the Population-Based HealthStreet Study. Journal of Immigrant and Minority Health. 2019;21(2):299–305. doi: 10.1007/s10903-018-0729-2.
    1. Ferdinand KC, Nedunchezhian S, Reddy TK. The COVID-19 and influenza “Twindemic”: Barriers to influenza vaccination and potential acceptance of SARS-CoV2 Vaccination in African-Americans. Journal of the National Medical Association. 2020 doi: 10.1016/j.jnma.2020.11.001.
    1. Quinn SC, Jamison AM, Freimuth V. Communicating effectively about emergency use authorization and vaccines in the COVID-19 pandemic. American Journal of Public Health. 2020 doi: 10.2105/AJPH.2020.306036.
    1. Shen AK, Hughes R, IV, DeWald E, Rosenbaum S, Pisani A, Orenstein W. Ensuring equitable access to COVID-19 vaccines in the US: Current system challenges and opportunities. Health Affairs. 2020 doi: 10.1377/hlthaff.2020.01554.
    1. Malik AA, et al. Determinants of COVID-19 vaccine acceptance in the US. EClinicalMedicine. 2020;26:100495. doi: 10.1016/j.eclinm.2020.100495.
    1. Khubchandani J, Saiki D, Kandiah J. Masks, gloves, and the COVID-19 pandemic: Rapid assessment of public behaviors in the United States. Epidemiologia. 2020;1(1):16–22. doi: 10.3390/epidemiologia1010004.
    1. Griffith DM, et al. Men and COVID-19: A biopsychosocial approach to understanding sex differences in mortality and recommendations for practice and policy interventions. Preventing Chronic Disease. 2020;17:E63. doi: 10.5888/pcd17.200247.
    1. Applewhite A, Stancampiano FF, Harris DM, Manaois A, Dimuna J, Glenn J, et al. A retrospective analysis of gender-based difference in adherence to influenza vaccination during the 2018-2019 season. Journal of Primary Care & Community Health. 2020 doi: 10.1177/2150132720958532.
    1. Bruine de Bruin W, Saw HW, Goldman DP. Political polarization in US residents’ COVID-19 risk perceptions, policy preferences, and protective behaviors. Journal of Risk and Uncertainty. 2020 doi: 10.1007/s11166-020-09336-3.

Source: PubMed

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