Chronic lymphocytic leukaemia genetics overview

Neil Caporaso, Lynn Goldin, Christoph Plass, George Calin, Gerald Marti, Steven Bauer, Elizabeth Raveche, Mary Lou McMaster, David Ng, Ola Landgren, Susan Slager, Neil Caporaso, Lynn Goldin, Christoph Plass, George Calin, Gerald Marti, Steven Bauer, Elizabeth Raveche, Mary Lou McMaster, David Ng, Ola Landgren, Susan Slager

Abstract

Although the familial aspect of chronic lymphocytic leukaemia (CLL) has been appreciated for decades, it is only with the recent confluence of improved molecular and gene technologies and world-wide collaborative networks that accelerated progress has become apparent. In this summary we highlight selected themes in the genetics of CLL emphasizing the opportunities and challenges of this malignancy.

Source: PubMed

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