Renal-related adverse effects of intravenous contrast media in computed tomography

Abstract

Renal-related adverse effects of intravascular contrast media (CM) include contrast-induced nephropathy in computed tomography and angiography. While large retrospective studies have been published, the exact pathogenesis of this condition is still unknown. We review the main international guidelines, including the American College of Radiology white paper and the guidelines of European Society of Urogenital Radiology, Royal College of Radiologists and Canadian Association of Radiologists, as well as their references, regarding this subject. We present a simplified, concise approach to renal-related adverse effects of CM, taking into consideration the basis for each recommendation in these published guidelines. This will allow the reader to better understand the rationale behind appropriate patient preparation for cross-sectional imaging.

Figures

Fig. 1

Mehran’s scoring system. CIN: contrast-induced nephropathy; CM: contrast media; Cr: creatinine; DM: diabetes mellitus; eGFR: estimated glomerular filtration rate; NYHA: New York Heart Association