Multimodal imaging reveals the role of γ activity in eating-reflex seizures
Thomas Blauwblomme, Philippe Kahane, Lorella Minotti, Frédéric Grouiller, Alexandre Krainik, Laurent Vercueil, Stéphan Chabardès, Dominique Hoffmann, Olivier David, Thomas Blauwblomme, Philippe Kahane, Lorella Minotti, Frédéric Grouiller, Alexandre Krainik, Laurent Vercueil, Stéphan Chabardès, Dominique Hoffmann, Olivier David
Abstract
In reflex epilepsies, alteration of γ oscillations may mediate transition between interictal and ictal states. Here, we explored a patient having seizures triggered by syrup intake. From intracranial electroencephalography combined with functional MRI, the overlap of the gustatory cortex and of the preictal and ictal onset zones, as defined by early gamma changes, motivated the successful resective surgery of the middle short gyrus of the right insula. This case provides a rare demonstration from human gamma activity that the route to seizure may be supported by the interplay between physiological and epileptogenic networks.
Conflict of interest statement
DISCLOSURE OF CONFLICTS OF INTEREST
None of the authors has any conflict of interest to disclose.
Figures
![Figure 1](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/3338065/bin/halms612950f1.jpg)
Source: PubMed