The Impact of Anxiety and Depression on the Quality of Life of Hemodialysis Patients

Chrysoula Vasilopoulou, Eirini Bourtsi, Sophia Giaple, Ioannis Koutelekos, Paraskevi Theofilou, Maria Polikandrioti, Chrysoula Vasilopoulou, Eirini Bourtsi, Sophia Giaple, Ioannis Koutelekos, Paraskevi Theofilou, Maria Polikandrioti

Abstract

Purpose: This study was to explore the impact of anxiety and depression on the quality of life of hemodialysis patients.

Material & methods: The sample studied consisted of 395 hemodialysis patients. Data was collected by the completion of a specially designed questionnaire for the needs of the present study which apart from socio-demographic and clinical, it also included HADS scale to assess the level of anxiety and depression as well as the scale Missoula-VITAS Quality of Life Index (MVQOLI) to assess patients' quality of life.

Results: The results of this study showed that 47.8% had high anxiety levels and 38.2% had high levels of depression. The average total score of quality of life was found to be 17.14. It was also shown that the total score of quality of life presented statistically significant association with family status (p=0.007), educational level (p<0.001), the number of children (p=0.001), patients' adherence to doctors' orders (p=0.003) and proposed diet (p=0.002) and the relations of patients with healthcare professionals and the other patients (p<0.001). The multiple linear regression showed that the overall quality of life score was statistically associated with the levels of depression after adjusted for possible confounders. More specifically, it was found that total score of quality of life was 2.5 and 4.4 points lower for patients with moderate and high levels of depression, respectively, compared to patients with low levels of depression (p<0.001).

Conclusions: Evaluation of anxiety and depression in conjunction with quality of life in hemodialysis patients should be an integral part of the therapeutic regimen.

Figures

Figure 1
Figure 1
Anxiety and depression levels

References

    1. Akman B, Uyar M, Afsar B, Sezer S, Ozdemir F. N, Haberal M. Adherence, depression and quality of life in patients on a renal transplantation waiting list. Transpl Int. 2007;20(8):682–7.
    1. Avramovic M, Stefanovic V. Health-related quality of life in different stages of renal failure. Artif Organs. 2012;36(7):581–9. .
    1. Birmelé B, Le Gall A, Sautenet B, Aguerre C, Camus V. Clinical, sociodemographic, and psychological correlates of health-related quality of life in chronic hemodialysispatients. Psychosomatics. 2012;53(1):30–7.
    1. Chilcot J, Wellsted D, Da Silva-Gane M, Farrington K. Depression on dialysis. Nephron Clin Pract. 2008;108(4):c25664. .
    1. Cohen S. D, Norris L, Acquaviva K, Peterson R. A, Kimmel P. L. Screening, diagnosis, and treatment of depression in patients with end-stage renal disease. Clin J Am Soc Nephrol. 2007;2(6):1332–42.
    1. Cruz L. N, Fleck M. P, Polanczyk C. A. Depression as a determinant of quality -of life in patients with chronic disease: data from Brazil. Soc Psychiatry Psychiatr Epidemiol. 2010;45(10):953–61. .
    1. Cukor D, Coplan J, Brown C, Friedman S, Cromwell-Smith A, Peterson R. A, Kimmel P. L. Depression and anxiety in urban hemodialysis patients. Clin J Am Soc Nephrol. 2007;2(3):484–490.
    1. Drayer R. A, Piraino B, Reynolds C. F, Houck P. R, Mazumdar S, Bernardini J, Rollman B. L. Characteristics of depression in hemodialysis patients: symptoms, quality of life and mortality risk. Gen Hosp Psychiatry. 2006;28(4):306–12.
    1. Feroze U, Martin D, Reina-Patton A, Kalantar-Zadeh K, Kopple J. D. Mental health, depression, and anxiety in patients on maintenance dialysis. Iran J Kidney Dis. 2010;4(3):173–80.
    1. Finkelstein F. O, Wuerth D, Finkelstein S. H. An approach to addressing depression in patients with chronic kidney disease. Blood Purif. 2010;29(2):121–4. .
    1. Hmwe N. T, Subramanian P, Tan L. P, Chong W. K. The effects of acupressure on depression, anxiety and stress in patients with hemodialysis: A randomized controlled trial. Int J Nurs Stud. 2015;52(2):509–18. .
    1. Iyasere O, Brown E. A. Determinants of quality of life in advanced kidney disease: time to screen? Postgrad Med J. 2014;90(1064):340–7. .
    1. Kimmel P. L, Patel S. S. Quality of life in patients with chronic kidney disease: focus on end-stage renal disease treated with hemodialysis. Semin Nephrol. 2006;26(1):68–79.
    1. Lee Y. J, Kim M. S, Cho S, Kim S. R. Association of depression and anxiety with reduced quality of life in patients with predialysis chronic kidney disease. Int J Clin Pract. 2013;67(4):363–8. .
    1. Levy N. B. What is psychonephrology ? J Nephrol. 2008;21(Suppl 13):S51–3.
    1. McCann K, Boore J. R. Fatigue in persons with renal failure who require maintenance haemodialysis. J Adv Nurs. 2000;32(5):1132–42.
    1. Michopoulos I, Douzenis A, Kalkavoura C, Christodoulou C, Michalopoulou P, Kalemi G, Lykouras L. Hospital Anxiety and Depression Scale (HADS): validation in a Greek general hospital sample. Annals of General Psychiatry. 2008;7(4):1–5. .
    1. Mstakidou K, Tsilika E, Parpa E, Katsouda E, Galanos A, Vlahos L. The Hospital Anxiety and Depression Scale in Greek cancer patients: psychometric analyses and applicability. Support Care Cancer. 2004;12(12):821–825.
    1. Olaqunju A. T, Campbell E. A, Adeyemi J. D. Interplay of anxiety and depression with quality of life in endstage renal disease. Psychosomatic. 2015;56(1):67–77. .
    1. Ossareh S, Tabrizian S, Zebarjadi M, Joodat R. S. Prevalence of depression in maintenance hemodialysis patients and its correlation with adherence to medications. Iran J Kidney Dis. 2014;8(6):467–74.
    1. Park H. C, Yoon H. B, Son M. J, Jung E. S, Joo K. W, Chin H. J, Oh Y. K. Depression and health-related quality of life in maintenance hemodialysis patients. Clin Nephrol. 2010;73(5):374–80.
    1. Preljevic V. T, Østhus T. B, Os I, Sandvik L, Opjordsmoen S, Nordhus I. H, Dammen T. Anxiety and depressive disorders in dialysis patients: association to health-related quality of life and mortality. Gen Hosp Psychiatry. 2013;35(6):619–24. .
    1. Stein M. B, Cox B. J, Afifi T. O, Belik S. L, Sareen J. Does co-morbid depressive illness magnify the impact of chronic physical illness? A population-based perspective. Psychol Med. 2006;36(5):587–59.
    1. Theofilou P. Association of insomnia symptoms with kidney disease quality of life reported by patients on maintenance dialysis. Psychol Health Med. 2013;18(1):70–8. .
    1. Theofilou P, Kapsalis F, Panagiotaki H. Greek version of MVQOLI - 15: Translation and cultural adaptation. International Journal of Caring Sciences. 2012;5(3):289–294.
    1. Turkistani I, Nuqali A, Badawi M, Taibah O, Alserihy O, Morad M, Kalantan E. The prevalence of anxiety and depression among end-stage renal disease patients on hemodialysis in Saudi Arabia. Rem Fail. 2014;36(10):1510–1515. .
    1. Unruh M. L, Hess R. Assessment of health-related quality of life among patients with chronic kidney disease. Adv Chronic Kidney Dis. 2007;14(4):345–52.
    1. Watnick S, Wang P. L, Demadura T, Ganzini L. Validation of 2 depression screening tools in dialysis patients. Am J Kidney Dis. 2005;46(5):919–924.
    1. Zigmond A. S, Snaith R. P. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand. 1983;67(6):361–370.

Source: PubMed

3
Abonneren