Minimally invasive procedures in severe acute pancreatitis treatment - assessment of benefits and possibilities of use

Jacek Szeliga, Marek Jackowski, Jacek Szeliga, Marek Jackowski

Abstract

Introduction: Acute pancreatitis (AP) consists of an extremely varied complex of pathological symptoms and clinical conditions, ranging from mild gastric complaints to multi-organ failure resulting in death.

Aim: To present the authors' own experience regarding surgical treatment for pancreatic necrosis complicated by infection using different methods, including classic and laparoscopic methods as well as those combined with percutaneous techniques.

Material and methods: In the period 2007-2010, 34 patients with the diagnosis of severe AP were treated at the Department of General, Gastroenterological and Oncological Surgery, Collegium Medicum, Nicolaus Copernicus University. In 7 patients classic necrosectomy with repeated peritoneal flushing was performed (type 1), in 5 patients laparotomy with active drainage (type 2), in 12 video-assisted retroperitoneal debridement (type 3), and in 10 only percutaneous drainage methods (type 4).

Results: Total duration of hospitalisation was from 10 to 192 days. The highest death rate was observed for type 1 procedures. Significant differences with regard to the absolute number of postoperative complications between different groups were not observed; however, their quality varied. Classic methods were used in patients whose general and local condition was more severe.

Conclusions: When AP and its complications are diagnosed, a suitable method of surgical treatment has to be selected extremely precisely and in an individualised way. Minimally invasive methods used in selected patients provide better outcomes and higher safety superseding classic, open techniques of surgical treatment.

Keywords: acute pancreatitis; infected pancreatic necrosis; video-assisted retroperitoneal debridement.

Figures

Photo 1
Photo 1
Flushing drainage after VARD
Photo 2
Photo 2
Sample tomograms of the abdominal cavity of a patient who had percutaneous drainage placed (A) and after VARD (B)

References

    1. Banks PA, Freeman ML. Practice guidelines in acute pancreatitis. Am J Gastroenterol. 2006;101:2379–400.
    1. Horvath K, Freeny P, Escallon J, et al. Safety and efficacy of video-assisted retroperitoneal debridement for infected pancreatic collections: a multicenter, prospective, single-arm phase 2 study. Arch Surg. 2010;145:817–25.
    1. Shelat VG, Diddapur RK. Minimally invasive retroperitoneal pancreatic necrosectomy in necrotising pancreatitis. Singapore Med J. 2007;48:220–3.
    1. Besselink MG, van Santvoort HC, Nieuwenhuijs VB, et al. Minimally invasive ‘step-up approach’ versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTERtrial): design and rationale of a randomised controlled multicenter trial. BMC Surg. 2006;6:6.
    1. van Santvoort HC, Besselink MG, Horvath KD, et al. Dutch Acute Pancreatis Study Group. Videoscopic assisted retroperitoneal debridement in infected necrotizing pancreatitis. HPB (Oxford) 2007;9:156–9.
    1. Yi F, Ge L, Zhao J, et al. Meta-analysis: total parenteral nutrition versus total enteral nutrition in predicted severe acute pancreatitis. Intern Med. 2012;51:523–30.
    1. Deng ZG, Zhou JY, Yin ZY, et al. Continuous regional arterial infusion and laparotomic decompression for severe acute pancreatitis with abdominal compartment syndrome. World J Gastroenterol. 2011;17:4911–6.
    1. Khorsandi M, Beatson K, Dougherty S, et al. Interventional radiology in acute pancreatitis: friend or Foe? J Pancreas (Online) 2012;13:91–3.
    1. Mier J, Leon E, Castillo A, et al. Early versus late necrosectomy in severe necrotzing pancreatitis. Am J Surg. 1997;173:71–5.
    1. Doctor N, Philip S, Gandhi V, et al. Analysis of the delayed approach to the management of infected pancreatic necrosis. World J Gastroenterol. 2011;17:366–71.
    1. Freeman ML, Werner J, van Santvoort HC, et al. Interventions for necrotizing pancreatitis: summary of a multidisciplinary consensus conference. Pancreas. 2012;41:1176–94.
    1. Bausch D, Wellner U, Kahl S, et al. Minimally invasive operations for acute necrotizing pancreatitis: comparison of minimally invasive retroperitoneal necrosectomy with endoscopic transgastricnecrosectomy. Surgery. 2012;152(3 Suppl.1):S128–34.
    1. Sileikis A, Beiša V, Beiša A, et al. Minimally invasive retroperitoneal necrosectomy in management of acute necrotizing pancreatitis. Videosurgery Miniinv. 2013;8:29–35.
    1. Carter R. Percutaneous management of necrotizing pancreatitis. HPB (Oxford) 2007;9:235–9.
    1. Connor S, Alexakis N, Raraty MG, et al. Early and late complications after pancreatic necrosectomy. Surgery. 2005;137:499–505.
    1. Castellanos G, Pinero A, Serrano A, et al. Translumbar retroperitoneal endoscopy: an alternative in the follow-up and management of drained infected pancreatic necrosis. Arch Surg. 2005;140:952–5.
    1. Beenen E, Brown L, Connor S. A comparison of the hospital costs of open vs. minimally invasive surgical management of necrotizing pancreatitis. HPB (Oxford) 2011;13:178–84.

Source: PubMed

3
Abonneren