Cystic fibrosis bone disease: Pathophysiology, assessment and prognostic implications
Abeer Anabtawi, Trang Le, Melissa Putman, Vin Tangpricha, Maria Luisa Bianchi, Abeer Anabtawi, Trang Le, Melissa Putman, Vin Tangpricha, Maria Luisa Bianchi
Abstract
Cystic fibrosis bone disease (CFBD) is a common long-term complication of cystic fibrosis (CF) that can lead to increased fractures and significant morbidity and mortality in this patient population. CFBD pathophysiology remains poorly understood and is likely to be multifactorial. There are limited studies evaluating diagnostic tools and tests to guide therapeutic decisions and monitoring of CFBD. This review will present and discuss the current evidence.
Keywords: Bone turn over markers; Cystic fibrosis; Cystic fibrosis bone disease; DXA.
Copyright © 2019 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
Source: PubMed