Prevalence and associated factors of pre-eclampsia among pregnant women attending anti-natal care at Mettu Karl referal hospital, Ethiopia: cross-sectional study

Alemayehu Sayih Belay, Tofik Wudad, Alemayehu Sayih Belay, Tofik Wudad

Abstract

Background: Preeclampsia is leading causes of maternal and perinatal morbidity and mortality worldwide and it is a hypertensive disorder which usually occurs after 20 weeks of gestation. In Ethiopia, according to Ethiopian National Emergency Obstetric and Newborn Care about 10% of all maternal mortality (direct and indirect) were due to preeclampsia. Despite this condition has adverse effects on the maternal and child health, its prevalence is still significant especially in developing countries including Ethiopia.

Objectives: The aim of the study is to assess the prevalence and associated factors of preeclampsia among pregnant women attending antenatal care at Mettu Karl referral hospital.

Method: The study was conducted at Mettu Karl referral hospital using institutional based cross sectional study design among women whose age was greater or equal to eighteen from March to April 2018. Data were collected from 129 participants by face to face interview technique using structured and pretested questionnaire. Logistic regression analysis was used to identify the factors associated with preeclampsia development.

Result: A total of 129 participants were enrolled in the study with the mean age of 25.87 [SD ± 4.757]. Prevalence of preeclampsia among the current pregnant women who attend ANC in Mettu Karl Hospital were 16 (12.4%) with 95% CI (7, 18). Predictor variables like respondents age (AOR = .009, 95% CI = [.000, .317]), current multiple pregnancy (AOR = .071, 95% CI = [.007, .773]) and history of diabetes mellitus (AOR = .058, 95% CI = [.007-.465]) were significantly associated with the current preeclampsia.

Conclusion: The finding of this study showed that a considerable proportion of women had preeclampsia. Health seeking behavior towards pregnant women's should be encouraged for both urban and rural residents, which provide a chance to diagnose preeclampsia as early as possible and to prevent the coming complication towards preeclampsia.

Keywords: Anti-natal care; Factors; Preeclampsia; Pregnant women; Prevalence.

Conflict of interest statement

Competing interestsThe authors declare that they have no competing interests.

References

    1. Davey D. A., Macgillivray I. The Classification and Definition of the Hypertensive Disorders of Pregnancy: Proposals Submitted to the International Society for the Study of Hypertension in Pregnancy. Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy. 1986;5(1):97–133. doi: 10.3109/10641958609023478.
    1. Gynecologists A. of O and, Pregnancy TF on H in Hypertension in pregnancy report of the American College of Obstetricians and Gynecologists’ task force on. Hypertens Pregnancy Obs Gynecol. 2013;122:1122–1131.
    1. Goldenberg RL, Rouse DJ. Prevention of premature birth. N Engl J Med. 1998;339(5):313–320. doi: 10.1056/NEJM199807303390506.
    1. Alkema L, Chou D, Hogan D, Zhang S, Moller A-B, Gemmill A, et al. Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN maternal mortality estimation inter-agency group. Lancet. 2016;387(10017):462–474. doi: 10.1016/S0140-6736(15)00838-7.
    1. Ethiopia - Demographic and Health Survey 2016 [ it appeared on 15 Oct 2018 10:26:16 GMT]; Available from: .
    1. Say L, Chou D, Gemmill A, Tunçalp Ö, Moller A-B, Daniels J, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014;2(6):e323–ee33. doi: 10.1016/S2214-109X(14)70227-X.
    1. WHO U. UNFPA, World Bank Group and the United Nations Population Division . Trends in maternal mortality: 1990 to 2015. Estimates by WHO, UNICEF. UNFPA. Geneva: World Bank Group and the United Nations population division; 2015.
    1. Lakew Y, Reda AA, Tamene H, Benedict S, Deribe K. Geographical variation and factors influencing modern contraceptive use among married women in Ethiopia: evidence from a national population based survey. Reprod Health. 2013;10(1):52. doi: 10.1186/1742-4755-10-52.
    1. Nakimuli A, Chazara O, Byamugisha J, Elliott AM, Kaleebu P, Mirembe F, et al. Pregnancy, parturition and preeclampsia in women of African ancestry. Am J Obstet Gynecol. 2014;210(6):510–520. doi: 10.1016/j.ajog.2013.10.879.
    1. Garomssa H, Dwivedi A. Maternal mortality in ambo hospital: a five year retrospective review. Ethiop J Reprod Health. 2008;2:1.
    1. Gaym A, Bailey P, Pearson L, Admasu K, Gebrehiwot Y. Disease burden due to pre-eclampsia/eclampsia and the Ethiopian health system's response. Int J Gynecol Obstet. 2011;115(1):112–116. doi: 10.1016/j.ijgo.2011.07.012.
    1. Moussa HN, Arian SE, Sibai BM. Management of hypertensive disorders in pregnancy. Women’s Health. 2014;10(4):385–404.
    1. Tessema GA, Tekeste A, Ayele TA. Preeclampsia and associated factors among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia: a hospital-based study. BMC Pregnancy Childbirth. 2015;15(1):73. doi: 10.1186/s12884-015-0502-7.
    1. Seyom E, Abera M, Tesfaye M, Fentahun N. Maternal and fetal outcome of pregnancy related hypertension in Mettu Karl referral hospital, Ethiopia. J Ovarian Res. 2015;8(1):10. doi: 10.1186/s13048-015-0135-5.
    1. Grum T, Seifu A, Abay M, Angesom T, Tsegay L. Determinants of pre-eclampsia/eclampsia among women attending delivery Services in Selected Public Hospitals of Addis Ababa, Ethiopia: a case control study. BMC Pregnancy Childbirth. 2017;17(1):307. doi: 10.1186/s12884-017-1507-1.
    1. Vata PK, Chauhan NM, Nallathambi A, Hussein F. Assessment of prevalence of preeclampsia from Dilla region of Ethiopia. BMC Res Notes. 2015;8(1):816. doi: 10.1186/s13104-015-1821-5.
    1. Kintiraki E, Papakatsika S, Kotronis G, Goulis DG, Kotsis V. Pregnancy-induced hypertension. Hormones. 2015;14(2):211–223. doi: 10.14310/horm.2002.1582.
    1. Klungsøyr K, Morken NH, Irgens L, Vollset SE, Skjærven R. Secular trends in the epidemiology of pre-eclampsia throughout 40 years in Norway: prevalence, risk factors and perinatal survival. Paediatr Perinat Epidemiol. 2012;26(3):190–198. doi: 10.1111/j.1365-3016.2012.01260.x.
    1. Schneider S, Freerksen N, Maul H, Roehrig S, Fischer B, Hoeft B. Risk groups and maternal-neonatal complications of preeclampsia–current results from the national German perinatal quality registry. J Perinat Med. 2011;39(3):257–265. doi: 10.1515/jpm.2011.010.
    1. Direkvand-Moghadam A, Khosravi A, Sayehmiri K. Predictive factors for preeclampsia in pregnant women: a unvariate and multivariate logistic regression analysis. Acta Biochim Pol. 2012;59(4):674.
    1. Zibaeenezhad MJ, Ghodsi M, Arab P, Gholzom N. The prevalence of hypertensive disorders of pregnancy in Shiraz, Southern Iran. 2010.
    1. Kimbally K, Barassoumbi H, Buambo S, Gombet T, Kibeke P, Monabeka H, et al. Arterial hypertension: epidemiological aspects and risk factors on pregnant and delivered woman. Dakar Med. 2007;52(2):148–152.
    1. Guerrier G, Oluyide B, Keramarou M, Grais RF. Factors associated with severe preeclampsia and eclampsia in Jahun, Nigeria. Int J Women's Health. 2013;5:509. doi: 10.2147/IJWH.S47056.
    1. Wolde Z, Segni H, Woldie M. Hypertensive disorders of pregnancy in Jimma University specialized hospital. Ethiop J Health Sci. 2011;21:3.
    1. Shamsi U, Saleem S, Nishter N, Ameen A. Epidemiology and risk factors of preeclampsia; an overview of observational studies. Al Ameen J Med Sci. 2013;6(4):292–300.
    1. Kashanian M, Baradaran HR, Bahasadri S, Alimohammadi R. Risk factors for pre-eclampsia: a study in Tehran, Iran. Arc Iran Med. 2011;14(6):412.
    1. Yossy S. Why does blood pressure rise with age? March 30. 2016.
    1. El-Moselhy EA, Khalifa HO, Amer SM, Mohammad KI, El-Aal HMA. Risk factors and impacts of pre-eclampsia: an epidemiological study among pregnant mothers in Cairo, Egypt. J Am Sci. 2011;7(5):311–323.
    1. English FA, Kenny LC, McCarthy FP. Risk factors and effective management of preeclampsia. Integr Blood Press Control. 2015;8:7.
    1. Bdolah Y, Lam C, Rajakumar A, Shivalingappa V, Mutter W, Sachs BP, et al. Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia? Am J Obstet Gynecol. 2008;198(4):428. e1–428. e6. doi: 10.1016/j.ajog.2007.10.783.
    1. Östlund I, Haglund B, Hanson U. Gestational diabetes and preeclampsia. Eur J Obstet Gynecol Reprod Biol. 2004;113(1):12–16. doi: 10.1016/j.ejogrb.2003.07.001.
    1. Schneider S, Freerksen N, Röhrig S, Hoeft B, Maul H. Gestational diabetes and preeclampsia–similar risk factor profiles? Early Hum Dev. 2012;88(3):179–184. doi: 10.1016/j.earlhumdev.2011.08.004.

Source: PubMed

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