Granulocyte transfusions in patients with chronic granulomatous disease and refractory infections: The NIH experience
Beatriz E Marciano, Elisabeth S Allen, Cathy Conry-Cantilena, Ervand Kristosturyan, Harvey G Klein, Thomas A Fleisher, Steven M Holland, Harry L Malech, Sergio D Rosenzweig, Beatriz E Marciano, Elisabeth S Allen, Cathy Conry-Cantilena, Ervand Kristosturyan, Harvey G Klein, Thomas A Fleisher, Steven M Holland, Harry L Malech, Sergio D Rosenzweig
Abstract
Granulocyte transfusions are a relatively safe adjunctive therapeutic option for patients with chronic granulomatous disease and severe/refractory bacterial or fungal infections. Early initiation, high frequency and sustained therapy is associated with significantly better outcomes.
Source: PubMed