Economic burden of maternal depression among women with a low income in Cape Town, South Africa

Susan Cleary, Stacey Orangi, Emily Garman, Hanani Tabani, Marguerite Schneider, Crick Lund, Susan Cleary, Stacey Orangi, Emily Garman, Hanani Tabani, Marguerite Schneider, Crick Lund

Abstract

Background: Maternal depression is a notable concern, yet little evidence exists on its economic burden in low- and middle-income countries.

Aims: This study assessed societal costs and economic outcomes across pregnancy to 12 months postpartum comparing women with depression with those without depression. Trial registration: ClinicalTrials.gov: NCT01977326 (registered on 24 October 2013); Pan African Clinical Trials Registry (www.pactr.org): PACTR201403000676264 (registered on 11 October 2013).

Method: Participants were recruited during the first antenatal visit to primary care clinics in Khayelitsha, Cape Town. In total, 2187 women were screened, and 419 women who were psychologically distressed were retained in the study. Women were interviewed at baseline, 8 months gestation and at 3 and 12 months postpartum; the Hamilton Rating Scale for Depression was used to categorise women as having depression or not having depression at each interview. Collected data included sociodemographics; health service costs; user fees; opportunity costs of accessing care; and travelling expenses for the women and their child(ren). Using Markov modelling, the incremental economic burden of maternal depression was estimated across the period.

Results: At 12 months postpartum, women with depression were significantly more likely to be unemployed, to have lower per capita household income, to incur catastrophic costs and to be in a poorer socioeconomic group than those women without depression. Costs were higher for women with depression and their child(ren) at all time points. Modelled provider costs were US$805 among women without depression versus US$1303 in women with depression.

Conclusions: Economic costs and outcomes were worse in perinatal women with depression. The development of interventions to reduce this burden is therefore of significant policy importance.

Keywords: Low and middle income countries; economic burden; maternal depression; societal costs.

Conflict of interest statement

None.

ICMJE forms are in the supplementary material, available online at https://doi.org/10.1192/bjo.2020.15.

Figures

Fig. 1
Fig. 1
Relationship between timing of interview and assumptions made to model costs during pregnancy and up to 12 months postpartum.
Fig. 2
Fig. 2
Public provider costs of care for mothers and their child(ren) (US$) by depression status.
Fig. 3
Fig. 3
Patient costs of accessing care for mothers and their child(ren) by depression status (US$).

References

    1. Lund C, Schneider M, Davies T, Nyatsanza M, Honikman S, Bhana A, et al. Task sharing of a psychological intervention for maternal depression in Khayelitsha, South Africa: study protocol for a randomized controlled trial. Trials 2014; 15: 457.
    1. Kathree T, Selohilwe OM, Bhana A, Petersen I. Perceptions of postnatal depression and health care needs in a South African sample: the “mental” in maternal health care. BMC Womens Health 2014; 14: 140.
    1. Ramchandani PG, Richter LM, Stein A, Norris SA. Predictors of postnatal depression in an urban South African cohort. J Affect Disord 2009; 113: 279–84.
    1. Rochat TJ, Tomlinson M, Bärnighausen T, Newell M-L, Stein A. The prevalence and clinical presentation of antenatal depression in rural South Africa. J Affect Disord 2011; 135: 362–73.
    1. Herba CM, Glover V, Ramchandani PG, Rondon MB. Maternal depression and mental health in early childhood: an examination of underlying mechanisms in low-income and middle-income countries. Lancet Psychiatry 2016; 3: 983–92. Available from: 10.1016/S2215-0366(16)30148-1.
    1. Gelaye B, Rondon MB, Araya R, Williams MA. Epidemiology of maternal depression, risk factors, and child outcomes in low-income and middle-income countries.Lancet Psychiatry 2016; 3: 973–82. Available from: 10.1016/S2215-0366(16)30284-X.
    1. Lund C, Breen A, Flisher AJ, Kakuma R, Corrigall J, Joska JA, et al. Poverty and common mental disorders in low and middle income countries: a systematic review. Soc Sci Med 2010; 71: 517–28.
    1. Lund C, Cois A. Simultaneous social causation and social drift: longitudinal analysis of depression and poverty in South Africa. J Affect Disord 2018; 229: 396–402. Available from: 10.1016/j.jad.2017.12.050.
    1. Saraceno B, van Ommeren M, Batniji R, Cohen A, Gureje O, Mahoney J, et al. Barriers to improvement of mental health services in low-income and middle-income countries. Lancet 2007; 370: 1164–74.
    1. Docrat S, Besada D, Cleary S, Daviaud E, Lund C. Mental health system costs, resources and constraints in South Africa: a national survey. Heal Policy Plan 2019; 34: 706–19. Available from: 10.1093/heapol/czz085.
    1. Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, et al. No health without mental health. Lancet 2007; 370: 859–77.
    1. Zimmerman M, Martinez JH, Young D, Chelminski I, Dalrymple K. Severity classification on the Hamilton Depression Rating Scale. J Affect Disord 2013; 150: 384–8.
    1. Drummond MF, Sculpher MJ, Claxton K, Stoddart GL, Torrance GW. Methods for the Economic Evaluation of Health Care Programmmes (4th ed). Oxford University Press, 2015.
    1. Lund C, Schneider M, Garman EC, Davies T, Munodawafa M, Honikman S, et al. Task-sharing of psychological treatment for antenatal depression in Khayelitsha, South Africa: effects on antenatal and postnatal outcomes in an individual randomised controlled trial. Behav Res Ther [Epub ahead of print] 31 Oct 2019. Available from: 10.1016/j.brat.2019.103466.
    1. Fox R, Goemaere E. They call it in Khayelitsha: the experience of Médecins Sans Frontières–South Africa in enrolling patients to receive antiretroviral treatment for HIV/AIDS. Camb Q Healthc Ethics 2006; 15: 302–12.
    1. Sheehan D, Lecrubier Y, Sheehan K, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998; 59 (suppl 20): 22–33.
    1. Cleary S, Birch S, Chimbindi N, Silal S, Mcintyre D. Investigating the affordability of key health services in South Africa. Soc Sci Med 2013; 80: 37–46.
    1. Foster N, Vassall A, Cleary S, Cunnama L, Churchyard G, Sinanovic E. The economic burden of TB diagnosis and treatment in South Africa. Soc Sci Med 2015; 130: 42–50. Available from: .
    1. X-RATES. Monthly Average South African Rand per 1 US Dollar. X-RATES, 2015 ().
    1. Western Cape Government: Health. Annual Report 2014/15 Western Cape Government, 2015 ().
    1. Palmer S, Raftery J. Economic Notes: opportunity cost. BMJ 1999; 318: 1551–2.

Source: PubMed

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