Relationship of diet to small and large adenomas of the sigmoid colon

S Kono, K Imanishi, K Shinchi, F Yanai, S Kono, K Imanishi, K Shinchi, F Yanai

Abstract

The relation of dietary factors to the risk of adenomas of the sigmoid colon was examined in men receiving a retirement health examination at the Self-Defense Forces Fukuoka Hospital between October 1986 and 1990. A total of 187 adenoma cases and 1557 controls with normal colonoscopy were identified in the series. Cases were further classified into small-adenoma (< 5 mm, n = 78) and large-adenoma (> or = 5 mm, n = 67) groups. The consumptions of selected foods and beverages were ascertained before colonoscopy by means of a self-administered questionnaire. After adjustment for smoking, alcohol use, rank and body mass index, low rice consumption and high meat intake were independently associated with an increased risk of large adenomas. The risk of small adenomas was not related to either rice consumption or meat intake. Adjusted odds ratios of large adenomas for the low, intermediate and high consumption levels of rice were estimated to be 1.0 (referent), 0.83 and 0.43, respectively (trend P = 0.08), and the corresponding figures for meat consumption were 1.0 (referent), 1.58 and 2.38, respectively (trend P = 0.02). The findings suggest that low rice consumption and high meat intake may promote the growth of colon adenomas, thereby increasing the risk of colon cancer.

References

    1. ) Correa , P. and Haenszel , W.The epidemiology of large‐bowel cancer . Adv. Cancer Res. , 26 , 1 – 141 ( 1978. ).
    1. ) Muto , T. , Bussey , H. J. R. and Morson , B. C.The evolution of cancer of the colon and rectum . Cancer , 36 , 2251 – 2270 ( 1975. ).
    1. ) O'Brien , M. J. , Winawer , S. J. , Zauber , A. G. , Gottlieb , L. S. , Sternberg , S. S. , Diaz , B. , Dickersin , G. R. , Ewing , S. , Geller , S. , Kasimian , D. , Komorowski , R. , Szporn , A. and The National Polyp Study Workgroup . The National Polyp Study: patients and polyp characteristics associated with high‐grade dysplasia in colorectal adenomas . Gastroenterology , 98 , 371 – 379 ( 1990. ).
    1. ) Vogelstein , B. , Fearon , E. R. , Hamilton , S. R. , Kern , S. E. , Preisinger , A. C. , Leppert , M. , Nakamura , Y. , White , R. , Smits , A. M. M. and Bos , J. L.Genetic alterations during colorectal‐tumor development . N. Engl. J. Med. , 319 , 525 – 532 ( 1988. ).
    1. ) Editorial. Colorectal cancer: new evidence for the adenoma/carcinoma sequence . Lancet , 340 , 210 – 211 ( 1992. ).
    1. ) Hill , M. J. , Morson , B. C. and Bussey , H. J. R.Aetiology of adenoma‐carcinoma sequence in large bowel . Lancet , i , 245 – 247 ( 1978. ).
    1. ) Hoff , G. , Moen , I. E. , Trygg , K. , Frølich , W. , Sauar , J. , Vatn , M. , Gjone , E. and Larsen , S.Epidemiology of polyps in the rectum and sigmoid colon: evaluation of nutritional factors . Scand. J. Gastroenterol. , 21 , 199 – 204 ( 1986. ).
    1. ) Macquart‐Moulin , G. , Riboli , E. , Cornée , J. , Kaaks , R. and Berthezène , P.Colorectal polyps and diet: a case‐control study in Marseilles . Int. J. Cancer , 40 , 179 – 188 ( 1987. ).
    1. ) Giovannucci , E. , Stampfer , M. J. , Colditz , G. , Rimm , E. B. and Willett , W. C.Relationship of diet to risk of colorectal adenoma in men . J. Natl. Cancer Inst. , 84 , 91 – 98 ( 1992. ).
    1. ) Kato , I. , Tominaga , S. , Matsuura , A. , Yoshii , Y. , Shirai , M. and Kobayashi , S.A comparative case‐control study of colorectal cancer and adenoma . Jpn. J. Cancer Res. , 81 , 1101 – 1108 ( 1990. ).
    1. ) Willett , W.The search for the causes of breast and colon cancer . Nature , 338 , 389 – 394 ( 1989. ).
    1. ) Trock , B. , Lanza , E. and Greenwald , P.Dietary fiber, vegetables, and colon cancer: critical review and meta‐analyses of the epidemiologic evidence . J. Natl. Cancer Inst. , 82 , 650 – 661 ( 1990. ).
    1. ) Kono , S. , Shinchi , K. , Ikeda , N. , Yanai , F. and Imanishi , K.Physical activity, dietary habits and adenomatous polyps of the sigmoid colon: a study of self‐defense officials in Japan . J. Clin. Epidemiol. , 44 , 1255 – 1261 ( 1991. ).
    1. ) Kono , S. , Ikeda , N. , Yanai , F. , Shinchi , K. and Imanishi , K.Alcoholic beverages and adenomatous polyps of the sigmoid colon: a study of male self‐defence officials in Japan . Int. J. Epidemiol. , 19 , 848 – 852 ( 1990. ).
    1. ) Honjo , S. , Kono , S. , Shinchi , K. , Imanishi , K. and Hirohata , T.Cigarette smoking, alcohol use and adenomatous polyps of the sigmoid colon . Jpn. J. Cancer Res. , 83 , 806 – 811 ( 1992. ).
    1. ) Harrell , F. E. , Jr.The LOGIST procedure . In “ SUGI Supplementary Library User's Guide, 1983 Edition ,” ed. Joyner S. P. , pp. 181 – 202 ( 1983. ). SAS Institute Inc. , Cary , North Carolina .
    1. ) Hirayama , T.Association between alcohol consumption and cancer of the sigmoid colon: observations from a Japanese cohort study . Lancet , ii , 725 – 727 ( 1989. ).
    1. ) Haenszel , W. , Locke , F. B. and Segi , M.A case‐control study of large bowel cancer in Japan . J. Natl. Cancer Inst. , 64 , 17 – 22 ( 1980. ).
    1. ) Macquart‐Moulin , G. , Riboli , E. , Cornée , J. , Charnay , B. , Berthezène , P. and Day , N.Case‐control study on colo‐rectal cancer and diet in Marseilles . Int. J. Cancer , 38 , 183 – 191 ( 1986. ).
    1. ) La Vecchia , C. , Negri , E. , Decarli , A. , D'Avanzo , B. , Gallotti , L. , Gentile , A. and Franceschi , S.A case‐control study of diet and colo‐rectal cancer in northern Italy . Int. J. Cancer , 41 , 492 – 498 ( 1988. ).
    1. ) Cummings , J. H. and Bingham , S. A.Dietary fibre, fermentation and large bowel cancer . Cancer Surv. , 6 , 601 – 621 ( 1987. ).
    1. ) Rosenberg , L.Coffee and tea consumption in relation to the risk of large bowel cancer: a review of epidemiologic studies . Cancer Lett. , 52 , 163 – 171 ( 1990. ).
    1. ) Jacobsen , B. K. , Kvåle , G. and Heuch , I.Coffee drinking and the risk of colon cancer: unfinished business . Epidemiology , 2 , 77 – 78 ( 1991. ).
    1. ) Yamane , T. , Hagiwara , N. , Tateishi , M. , Akachi , S. , Kim , M. , Okuzumi , J. , Kitao , Y. , Inagake , M. , Kuwata , K. and Takahashi , T.Inhibition of azoxymethane‐induced colon carcinogenesis in rat by green tea polyphenol fraction . Jpn. J. Cancer Res. , 82 , 1336 – 1339 ( 1991. ).

Source: PubMed

Sponsors en medewerkers

Medische omstandigheden

Geneesmiddelinterventies

3
Abonneren