Single-Step Transepithelial PRK vs Alcohol-Assisted PRK in Myopia and Compound Myopic Astigmatism Correction

Bartlomiej J Kaluzny, Iwona Cieslinska, Samuel A Mosquera, Shwetabh Verma, Bartlomiej J Kaluzny, Iwona Cieslinska, Samuel A Mosquera, Shwetabh Verma

Abstract

Transepithelial photorefractive keratectomy (tPRK), where both the epithelium and stroma are removed in a single-step, is a relatively new procedure of laser refractive error correction. This study compares the 3-month results of myopia and compound myopic astigmatism correction by tPRK or conventional alcohol-assisted PRK (aaPRK).This prospective, nonrandomized, case-control study recruited 148 consecutive patients; 93 underwent tPRK (173 eyes) and 55 aaPRK (103 eyes). Refractive results, predictability, safety, and efficacy were evaluated during the 3-month follow-up. The main outcome measures were uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and mean refractive spherical equivalent (MRSE).Mean preoperative MRSE was -4.30 ± 1.72 D and -4.33 ± 1.96 D, respectively (P = 0.87). The 3-month follow-up rate was 82.1% in the tPRK group (n = 145) and 86.4% in aaPRK group (n = 90), P = 0.81. Postoperative UDVA was 20/20 or better in 97% and 94% of eyes, respectively (P = 0.45). In the tPRK and aaPRK groups, respectively, 13% and 21% of eyes lost 1 line of CDVA, and 30% and 31% gained 1 or 2 lines (P = 0.48). Mean postoperative MRSE was -0.14 ± 0.26 D in the tPRK group and -0.12 ± 0.20 D in the aaPRK group (P = 0.9). The correlation between attempted versus achieved MRSE was equally high in both groups.Single-step transepithelial PRK and conventional PRK provide very similar results 3 months postoperatively. These procedures are predictable, effective, and safe for correction of myopia and compound myopic astigmatism.

Conflict of interest statement

The authors have no funding and conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Comparison of uncorrected distance visual acuity (A), change in corrected distance visual acuity (B), and attempted vs achieved spherical equivalent (C) in single-step transepithelial photorefractive keratectomy (tPRK; left panels) and alcohol-assisted photorefractive keratectomy (aaPRK; right panels) groups.
FIGURE 2
FIGURE 2
Comparison of the spherical equivalent refractive accuracy (D), refractive astigmatism (E), and stability of spherical equivalent refraction (F) in single-step transepithelial photorefractive keratectomy (tPRK; left panels) and alcohol-assisted photorefractive keratectomy (aaPRK; right panels) groups.

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