Interactive visuo-motor therapy system for stroke rehabilitation

Kynan Eng, Ewa Siekierka, Pawel Pyk, Edith Chevrier, Yves Hauser, Monica Cameirao, Lisa Holper, Karin Hägni, Lukas Zimmerli, Armin Duff, Corina Schuster, Claudio Bassetti, Paul Verschure, Daniel Kiper, Kynan Eng, Ewa Siekierka, Pawel Pyk, Edith Chevrier, Yves Hauser, Monica Cameirao, Lisa Holper, Karin Hägni, Lukas Zimmerli, Armin Duff, Corina Schuster, Claudio Bassetti, Paul Verschure, Daniel Kiper

Abstract

We present a virtual reality (VR)-based motor neurorehabilitation system for stroke patients with upper limb paresis. It is based on two hypotheses: (1) observed actions correlated with self-generated or intended actions engage cortical motor observation, planning and execution areas ("mirror neurons"); (2) activation in damaged parts of motor cortex can be enhanced by viewing mirrored movements of non-paretic limbs. We postulate that our approach, applied during the acute post-stroke phase, facilitates motor re-learning and improves functional recovery. The patient controls a first-person view of virtual arms in tasks varying from simple (hitting objects) to complex (grasping and moving objects). The therapist adjusts weighting factors in the non-paretic limb to move the paretic virtual limb, thereby stimulating the mirror neuron system and optimizing patient motivation through graded task success. We present the system's neuroscientific background, technical details and preliminary results.

References

    1. Exp Brain Res. 1988;71(3):491-507
    1. Arch Phys Med Rehabil. 2005 Aug;86(8):1616-22
    1. J Clin Neurophysiol. 2004 May-Jun;21(3):157-69
    1. Hum Brain Mapp. 2000 Dec;11(4):273-85
    1. Brain Lang. 2004 May;89(2):370-6
    1. Arch Phys Med Rehabil. 1994 Apr;75(4):394-8
    1. J Neurophysiol. 2004 May;91(5):2376-9
    1. Cyberpsychol Behav. 2005 Jun;8(3):187-211; discussion 212-9
    1. Eur J Neurosci. 2001 Jan;13(2):400-4
    1. Neurorehabil Neural Repair. 2006 Dec;20(4):503-7
    1. J Neurosci. 1998 Aug 15;18(16):6539-48
    1. Restor Neurol Neurosci. 2004;22(3-5):281-99
    1. Brain. 1998 Sep;121 ( Pt 9):1603-30
    1. Arch Phys Med Rehabil. 1999 Jun;80(6):624-8
    1. Neuropsychologia. 1999 Feb;37(2):147-58
    1. Artif Organs. 2002 Mar;26(3):219-23
    1. Neuromodulation. 2003 Apr;6(2):108-15
    1. J Neurosci. 2005 Oct 12;25(41):9339-46
    1. Scand J Rehabil Med. 1997 Mar;29(1):3-10
    1. Lancet. 1999 Jun 12;353(9169):2035-6
    1. Conf Proc IEEE Eng Med Biol Soc. 2005;3:2547-50
    1. Neuron. 2003 Sep 11;39(6):1053-8
    1. Curr Opin Neurol. 2003 Dec;16(6):705-10
    1. Stroke. 2004 Jun;35(6):1410-4
    1. Stroke. 2006 Jul;37(7):1941-52
    1. J Neuroeng Rehabil. 2004 Oct 26;1(1):5
    1. J Neurophysiol. 1995 Jun;73(6):2608-11
    1. Curr Atheroscler Rep. 2002 Jul;4(4):270-6
    1. Arch Phys Med Rehabil. 2003 Jul;84(7):1090-2
    1. Arch Phys Med Rehabil. 2006 Jun;87(6):842-52

Source: PubMed

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