Multimodal Analgesia in Total Knee Arthroplasty: A Randomized, Double-Blind, Controlled Trial on Additional Efficacy of Periarticular Anesthesia
Patrizia Milani, Piergiorgio Castelli, Massimo Sola, Marco Invernizzi, Giuseppe Massazza, Carlo Cisari, Patrizia Milani, Piergiorgio Castelli, Massimo Sola, Marco Invernizzi, Giuseppe Massazza, Carlo Cisari
Abstract
Pain management is a main determinant of functional recovery after total knee arthroplasty (TKA). We performed a randomized, controlled, double blind study to evaluate additive efficacy of periarticular anesthesia in patients undergoing TKA in reducing post-operative pain, operated limb edema and improving post-operative mobility. Patients were randomly assigned to study or control group; all subjects received the same analgesic protocol; before wound closure, the study group received also a periarticular anesthesia (ropivacaine 1% 20 mL). The results show no statistical differences in any of the variable evaluated. Our data suggest that additive periarticular anesthetic protocol with ropivacaine 1% 20 mL is not superior to oral and intravenous analgesia alone in patients undergoing TKA, regarding post-operative pain control, operated limb edema reduction and post-operative mobility improvement.
Keywords: analgesia; arthroplasty; knee replacement; outcome; periarticular injection; range of motion.
Copyright © 2015 Elsevier Inc. All rights reserved.
Source: PubMed