Lactate levels with glioblastoma multiforme
Arunpreet Singh Kahlon, Mariam Alexander, Arundeep Kahlon, Jonathan Wright, Arunpreet Singh Kahlon, Mariam Alexander, Arundeep Kahlon, Jonathan Wright
Abstract
A 37-year-old woman with known glioblastoma multiforme was admitted for treatment of new deep vein thrombosis. Anion gap and plasma lactate levels were found to be elevated. Magnetic resonance imaging of the brain showed a stable, advanced glioblastoma multiforme. All causes of lactic acidosis, including infections and medications, were ruled out. Aggressive tumors have been shown to produce lactate levels in minute quantities in their microenvironment, which helps them metastasize and evade immune response and even radiation.
Figures
MRI of the brain showing glioblastoma multiforme in the right brain stem.
Source: PubMed