Reducing the Risk of Developing Major Depression in Adolescents/Young Adults With Minor Depression/Depression Symptoms
27. mars 2014 oppdatert av: University of Chicago
Randomized Trial of a Motivational Interview Versus Brief Advice in Primary Care to Engage Mid-Late Adolescents With a Web-based Depression Prevention Intervention
The purpose of this research study is to assess the feasibility of a combined primary care/web-based depression prevention intervention. Primary care physicians (PCP) currently lack an alternative behaviorally-based approach to antidepressant medications for individuals with depression symptoms or minor depression, but who have not yet developed Major Depression.
The objective of this study is to compare the feasibility and efficacy of motivational interviewing (MI) versus brief advice in primary care to engage adolescents with a web-based depression prevention intervention.
Studieoversikt
Status
Avsluttet
Forhold
Intervensjon / Behandling
Detaljert beskrivelse
There is no population-based approach to prevent the onset of major depression in adolescence.
Adolescents with current sub-threshold depression symptoms (not meeting criteria for major depression, 5 < symptoms including depressed mood, irritability or loss of pleasure), a personal history of a depressive episode in the past or with a family history of depressive disorders are at increased risk.
Because most adolescents have regular contact with primary care physicians, the primary care clinics could provide a setting to disseminate evidence-based preventive approaches.
We have developed a combined primary care/Web-based preventive intervention to reduce the risk of developing depressive disorders in adolescents and young adults by adapting interventions of demonstrated benefit in study settings to a primary care/Web-based format in collaboration with leading investigators in the field.
The goal of this research program is to evaluate the feasibility and possible efficacy of an alternative delivery mechanism for evidence-based behavioral approaches to depression treatment and prevention that have already demonstrated benefit with face-to-face delivery in study settings.
Each component this intervention will need to be carefully evaluated for acceptability, safety, feasibility and efficacy.
The focus of this study is the primary care component.
Studietype
Observasjonsmessig
Registrering (Faktiske)
93
Kontakter og plasseringer
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Studiesteder
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Illinois
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Chicago, Illinois, Forente stater, 60637
- University of Chicago
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Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
14 år til 75 år (Barn, Voksen, Eldre voksen)
Tar imot friske frivillige
Ja
Kjønn som er kvalifisert for studier
Alle
Prøvetakingsmetode
Ikke-sannsynlighetsprøve
Studiepopulasjon
- Subjects are between the ages of 14-18 years and
- have one risk factor for developing depression in the next two years:
- sub-clinical depressed mood (not meeting criteria of major depression),
- a family history of depression in a parent or sibling, or
- past personal history of depression or personal perception of risk depression and desire to participate
Beskrivelse
Inclusion criteria include:
- (1) age 14-18 years and
- (2) one risk factor for developing depression in the next two years: sub-clinical depressed mood (not meeting criteria of major depression),
- a family history of depression in a parent or sibling, or past personal history of depression or personal perception of risk depression and desire to participate
Exclusion Criteria:
- criteria include meeting criteria or undergoing active treatment for major depression (5 or more symptoms nearly every day with functional impairment, minor depression),
- bipolar disorder,
- panic disorder,
- conduct disorder,
- substance abuse or having suicidal ideation.
- Active treatment for depression is defined as receiving anti-depressant medication or counseling within one year of remission of symptoms from the most recent episode.
- Those who meet DSM-IV criteria for minor depression (3-4 symptoms) or who report significant functional impairment (very difficult or above on the Prime MD functional impairment scale) will be notified and offered a referral for an evaluation by a mental health specialist (and will be strongly encouraged to attend).
- Those with 1-2 symptoms of depression will also be offered evaluation and treatment from a mental health specialist. In each case, the primary care physician will be notified and the parents (if under the age of 19).
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
Kohorter og intervensjoner
Gruppe / Kohort |
Intervensjon / Behandling |
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1
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2
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3
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motivational interviewing, brief advice in primary care
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Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart
1. mai 2006
Primær fullføring (Faktiske)
1. september 2007
Studiet fullført (Faktiske)
1. desember 2011
Datoer for studieregistrering
Først innsendt
1. september 2005
Først innsendt som oppfylte QC-kriteriene
2. september 2005
Først lagt ut (Anslag)
5. september 2005
Oppdateringer av studieposter
Sist oppdatering lagt ut (Anslag)
28. mars 2014
Siste oppdatering sendt inn som oppfylte QC-kriteriene
27. mars 2014
Sist bekreftet
1. mars 2014
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- 13798A
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