Venous Thromboembolism and Bleeding in Hospitalized Medical Patients With Cancer
Patients with cancer hospitalized for an acute medical illness have an increased risk of venous thromboembolic events. Although international guidelines suggest the use of thromboprophylaxis in these patients, the recommendations are based on studies which included a percentage of patients with cancer without primarily focusing on this high risk group.
Since patients with cancer present an increased risk of bleeding complications it is critical to evaluate the safety of thromboprophylaxis in the cancer group. Recent studies suggest a limited use of thromboprophylaxis in these patients.
The aim of this study is to evaluate the use, efficacy and safety of thromboprophylaxis in medical cancer patients hospitalized for an acute medical disease.
Design: observational, prospective study Primary end-point: incidence of major and clinically relevant non major bleeding during hospitalization Secondary endpoints: frequency of use, doses and contraindications for pharmacological thromboprophylaxis; venous thromboembolic events up to three months after discharge
Studieöversikt
Status
Betingelser
Studietyp
Inskrivning (Faktisk)
Kontakter och platser
Studieorter
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Chieti, Italien, 66100
- Universita degli Studi G. d'Annunzio Chieti e Pescara
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Deltagandekriterier
Urvalskriterier
Åldrar som är berättigade till studier
Tar emot friska volontärer
Kön som är behöriga för studier
Testmetod
Studera befolkning
Beskrivning
Inclusion Criteria:
- all patients with cancer hospitalized for an acute medical illness
Exclusion Criteria:
- current use of oral or parenteral anticoagulant treatment
- no informed consent to participate
Studieplan
Hur är studien utformad?
Designdetaljer
- Observationsmodeller: Kohort
- Tidsperspektiv: Blivande
Vad mäter studien?
Primära resultatmått
Resultatmått |
Tidsram |
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Major bleeding and clinically relevant non major bleeding
Tidsram: Participants will be followed for the duration of hospital stay, an expected average of 1 week
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Participants will be followed for the duration of hospital stay, an expected average of 1 week
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Sekundära resultatmått
Resultatmått |
Tidsram |
|---|---|
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Venous thromboembolism
Tidsram: Participants will be followed up to 3 months after discharge, an expected average of 13 weeks
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Participants will be followed up to 3 months after discharge, an expected average of 13 weeks
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Minor bleeding
Tidsram: Participants will be followed for the duration of hospital stay, an expected average of 1 week
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Participants will be followed for the duration of hospital stay, an expected average of 1 week
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Samarbetspartners och utredare
Sponsor
Studieavstämningsdatum
Studera stora datum
Studiestart
Primärt slutförande (Faktisk)
Avslutad studie (Faktisk)
Studieregistreringsdatum
Först inskickad
Först inskickad som uppfyllde QC-kriterierna
Första postat (Uppskatta)
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
Senast verifierad
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- ChietiOnco2
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