Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study (MBSRforPTSD)
Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study
PTSD is a common consequence of war, for soldiers and civilians. PTSD results in hyperarousal, avoidance, numbing, and re-experiencing, causing persistent decreased quality of life. Mindfulness involves the ability to bring attention to the present moment without judgment; this ability is correlated with measures of mental health. Within health care, mindfulness is taught as an 8-week course called Mindfulness-Based Stress Reduction (MBSR). MBSR is unstudied for PTSD. We propose to assess the feasibility of MBSR as an intervention for PTSD, since it may affect hypervigilance, avoidance, and reactivity associated with this disorder.
Specific Aims: Aim 1: Assess the feasibility of recruiting and retaining a sample of veterans with PTSD to complete a study protocol that involves randomization to usual care or usual care plus MBSR. Aim 2: Apply measures of PTSD symptom severity, depression and quality of life before and after randomization, to assess whether there is evidence of benefit and whether MBSR warrants further study for PTSD, and allow calculation of standardized effect sizes. Aim 3: Apply a validated measure of mindfulness before and after treatment. Aim 4: Explore the relationship between PTSD symptoms, mindfulness score, and frequency of meditation practice.
研究概览
研究类型
注册 (预期的)
阶段
- 不适用
联系人和位置
学习地点
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Washington
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Seattle、Washington、美国、98108
- VA Puget Sound Health Care System
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-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Must have PTSD
Exclusion Criteria:
- Active substance use
- Active suicidal ideations
- Borderline or antisocial personality disorder
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:无(打开标签)
武器和干预
参与者组/臂 |
干预/治疗 |
---|---|
实验性的:MBSR
An 8-week course in mindfulness-based stress reduction (MBSR)
|
An 8-week course in mindfulness training
|
无干预:2
Treatment as usual
|
研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
---|---|
PTSD symptom score
大体时间:baseline, after MBSR and 4 months later
|
baseline, after MBSR and 4 months later
|
次要结果测量
结果测量 |
大体时间 |
---|---|
depression (PHQ9)
大体时间:baseline, after MBSR and 4 months later
|
baseline, after MBSR and 4 months later
|
合作者和调查者
调查人员
- 首席研究员:David Kearney, MD、VA Puget Sound Health Care System
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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