PET-CT in Diagnosis of Pancreatic Cystic Neoplasms
研究概览
详细说明
Today, in clinical practice the diagnosis pancreatic cystic neoplasms are based on MDCT, MRI and ERCP followed by surgical exploration. The information gained by conventional imaging modalities is restricted to the morphological details, which usually is insufficient for the definitive staging of the pancreatic cystic neoplasms. Based on these previous studies, it seems that PET especially combined with CT modality could improve the diagnostic accuracy of the pancreatic cystic lesions.
So far, there are only few cases published concerning the role of 18F-FDG-PET-CT in the differential diagnosis of cystic pancreatic lesions. Therefore, more studies are needed to determine the role of combined 18F-FDG-PET-CT in the diagnosis of pancreatic cystic lesions.
The aim of the current project is to evaluate the possibility to enhance the diagnostic accuracy by using the combined 18F-FDG-PET-CT imaging in patients with pancreatic cystic neoplasms by combining PET-CT with MRI and MDCT.
The study consists of 20-30 patients with pancreatic cystic neoplasms. The patients enrolled in the study will be imaged by MDCT, MRI combined with magnetic resonance cholangiopancreatography (MRCP), endoscopic retrograde cholangiopancreatography (ERCP) and 18F-FDG-PET-CT followed by surgery or follow-up. The data will be collected between 2011 and 2013.
研究类型
注册 (实际的)
联系人和位置
学习地点
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Turku、芬兰、20521
- Turku University Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- suspicion of pancreatic cystic neoplasm using US, MDCT, MRI and/or ERCP
- laparotomy planned because of the lesion
- signed informed consent
Exclusion Criteria:
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学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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Patients having pancreatic cystic lesion
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
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Predictive Value of PET/CT imaging for Identifying Malignant and Benign Pancreatic Cystic Lesions
大体时间:1 mo
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To determine sensitivities, specificities, accuracy and positive/negative predictive values of PET/CT imaging for differentiating malignant and benign cystic lesions in patients who are to undergo surgical resection.
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1 mo
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次要结果测量
结果测量 |
大体时间 |
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To compare PET/CT to ERCP, MDCT and MRI-MRCP
大体时间:1 mo
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1 mo
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合作者和调查者
调查人员
- 首席研究员:Saila Kauhanen, PhD、Turku University Hospital
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
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