A Correlation Between Hair Cortisol Levels and the Development of Post Traumatic Stress Disorder (PTSD)
This observational study follows subjects who have been exposed to a traumatic event and are at risk of developing PTSD symptoms. Participants are recruited within six hours of a traumatic event, and, starting from the recruitment session, are then examined on six set points of time within a period of thirteen months. The examinations include both biological studies of cortisol in hair, blood and saliva, and psychological examinations and questionaires that assess the development and severity of PTSD symptoms.
The novel method of sampling hair cortisol allows investigators to retroactively estimate the mean levels of blood cortisol during the tree months prior to the sampling.
The study aims at further illuminating the correlation between cortisol levels both prior and following a traumatic event, and the development and severity of PTSD symptoms
研究概览
地位
条件
研究类型
注册 (预期的)
联系人和位置
学习地点
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Tel Hashomer、以色列、52621
- Chaim Sheba Medical Center
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Age 18-70.
- Experienced a traumatic and were at risk (or perceived risk) of serious injury to themselves or others in their surroundings.
- Signed an informed consent form.
Exclusion Criteria:
- Age under 18 or over 70.
- Severe or complex physical injury, such as severe head trauma, massive burns or injuries that require surgery under full anesthesia.
- A personal history of Psychotic state or PTSD.
- Pregnancy
- Weight below 45 Kg or over 120 Kg.
- Hair shorter than 1.5 cm.
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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Participants exposed to tramautic event
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
---|---|
PTSD diagnosis and symptom severity as measured by Clinician Administered PTSD Scale (CAPS).
大体时间:13 months
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13 months
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合作者和调查者
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- SHEBA-13-0910-JZ-CTIL
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