Dexmedetomidine and Laparoscopic Surgery
The Effect of Adding Intrathecal Dexmedetomidine on Shoulder Tip Pain During Laparoscopic Ovarian Cystectomy Under Bupivacaine Spinal Anaesthesia. Randomised Controlled Study.
Conventionally General anaesthesia remains the choice for the majority of open abdominal surgical procedures, and regional anaesthesia is preferred only for patients who are at high risk under general anaesthesia . The main reason for selecting spinal anaesthesia as the first choice for laparoscopic cases was its advantages over general anaesthesia which include uniform total muscle relaxation, a conscious patient, economical, relatively uneventful recovery, pain free early postoperative period and the protection from potential complications of general anaesthesia. The main debatable point, however, seems to be the status of respiratory parameters among the two modes of anaesthesia during laparoscopic surgery. In this context it can be stated that spontaneous physiological respiration during spinal anaesthesia would always be better than an assisted respiration as in general anaesthesia.
The pneumo-peritoneum induced rise in intra-abdominal pressure including pressure on the diaphragm and carbon dioxide induced peritoneal irritation are the factors to be considered
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Assiut、埃及、71111
- Assiut University
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Elective gynaecological laparoscopic surgery
- Age 20-45 yrs
- Suspected surgery time 30 minutes
- Inflation pressure <13 Cm H20
Exclusion Criteria:
- Contraindications to regional block (infection at the needle insertion site)
- Altered conscious level.
- Pregnancy
- Body mass index >35
- Height <155 cm
- Patients who have difficulty understanding the study protocol
学习计划
研究是如何设计的？
设计细节
- 主要用途：预防
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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其他：control group
will receive 3.5 ml (17.5 mg) hyperbaric Bupivacaine + 0.5 ml saline
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intravenous flluid
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其他：Dexmedetomidine group
will receive 3.5 ml (17.5 mg) hyperbaric Bupivacaine + 0.5 ml dexmedetomidine (0.5 mic)
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anaesthetic adjuvants and pain killer medication.
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研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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occurrence shoulder tip pain
大体时间：48 hours
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48 hours
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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intraoperative haemodynamic stability, et co2, sao2.
大体时间：2 hours
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2 hours
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Normal saline的临床试验
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Julphar Gulf Pharmaceutical IndustriesParexel; Profil Institut für Stoffwechselforschung GmbH完全的