Characterizing Orthodontic Tooth Movement With Photographic Scans

December 1, 2025 updated by: Flavio Uribe, UConn Health

Characterizing Orthodontic Tooth Movement in Real Time Using Dental Monitoring Scans: a Pilot Study

Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans. Canine retraction over the course of 1 orthodontic visit will be measured.

Study Overview

Status

Status

Indicates the current recruitment status or the expanded access status.
Completed

Conditions

Conditions

The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.

Intervention / Treatment

Intervention / Treatment

A process or action that is the focus of a clinical study. Interventions include drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available. Interventions can also include noninvasive approaches, such as education or modifying diet and exercise.

Detailed Description

The accuracy and reliability of Dental Monitoring scans is be evaluated and compared to that of iTero digital scans during maxillary canine retraction. The magnitude and type of tooth movement occurring in a one month period in patients undergoing maxillary canine retraction will be measured. Patients undergoing orthodontic treatment in the Center for Orthodontic Care at UConn Health will be evaluated for the inclusion criteria. A total of twenty patients whose orthodontic treatment plan required extraction of at least one premolar in the maxillary arch will be recruited. The patient will be required to take photographs and video scans as dictated by Dental Monitoring (DM) on the first and final days of the study period (four weeks), while iTero scans are taken by the provider in clinic on these same days. Patient will also be periodically taking photographic scans at home using Dental Monitoring. The DM scans taken by the patient will be compared to the iTero digital scans taken by the provider. This can be done by superimposing the stereolithographic (STL) files created from each scan and assessing the amount of deviation between the 3D models. The types of tooth movement occurring during canine retraction in buccolingual, mesiodistal, and incisogingival planes will be quantified using Doctor Dashboard software available in DM. DM's 3D matching technology allows superimposition of teeth from each 3D model created per scan. Each tooth and its movements are graphed in a detailed manner to provide precise information about its type of movement.

Study Type

Study Type

Describes the nature of a clinical study. Study types include interventional studies (also called clinical trials), observational studies (including patient registries), and expanded access.
Interventional

Enrollment (Actual)

Enrollment

The number of participants in a clinical study. The "anticipated" enrollment is the target number of participants that the researchers need for the study.
36

Phase

Phase

The stage of a clinical trial studying a drug or biological product, based on definitions developed by the U.S. Food and Drug Administration (FDA). The phase is based on the study's objective, the number of participants, and other characteristics. There are five phases: Early Phase 1 (formerly listed as Phase 0), Phase 1, Phase 2, Phase 3, and Phase 4. Not Applicable is used to describe trials without FDA-defined phases, including trials of devices or behavioral interventions.
  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact

The name and contact information for the person who can answer enrollment questions for a clinical study. Each location where the study is being conducted may also have a specific contact, who may be better able to answer those questions.

Study Contact Backup

Study Locations

  • United States
    • Connecticut
      • Farmington, Connecticut, United States, 06030
        • UConn Health

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Eligibility Criteria

The key requirements that people who want to participate in a clinical study must meet or the characteristics they must have. Eligibility criteria consist of both inclusion criteria (which are required for a person to participate in the study) and exclusion criteria (which prevent a person from participating). Types of eligibility criteria include whether a study accepts healthy volunteers, has age or age group requirements, or is limited by sex.

Ages Eligible for Study

11 years and older (Child, Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Patients with fixed orthodontic appliances
  • Treatment plan requiring extraction of at least one maxillary premolar
  • Male and female
  • Permanent dentition from first molar to first molar in the maxilla
  • Teeth with normal crown morphology
  • Fully erupted canines
  • Above 11 years of age
  • Patients with any cellular phone with a camera

Exclusion Criteria:

  • Lack of extraction in orthodontic treatment plan
  • Syndromic patients
  • Cleft lip/palate patients
  • Removable appliances

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm

Participant Group / Arm

A group or subgroup of participants in a clinical trial that receives a specific intervention/treatment, or no intervention, according to the trial's protocol.
Intervention / Treatment

Intervention / Treatment

A process or action that is the focus of a clinical study. Interventions include drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available. Interventions can also include noninvasive approaches, such as education or modifying diet and exercise.
Experimental: Canine retraction arm
Canine retraction
Device: Monitoring Tooth Movement
Monitoring Canine Retraction

What is the study measuring?

Primary Outcome Measures

Primary Outcome Measures

In a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment. Most clinical studies have one primary outcome measure, but some have more than one.
Outcome Measure
Measure Description
Time Frame
Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan
Time Frame: Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)
Deviation between the photographic and intraoral scan will be measured via root mean square (RMS) in millimeters (mm).
Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)

Secondary Outcome Measures

Secondary Outcome Measures

In a clinical study's protocol, a planned outcome measure that is not as important as the primary outcome measure for evaluating the effect of an intervention but is still of interest. Most clinical studies have more than one secondary outcome measure.
Outcome Measure
Measure Description
Time Frame
Tracking Maxillary Canine Tooth Movement (Displacement)
Time Frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Magnitude of canine tooth movement for every 4-5 days during a one month period. Measurements will be done in mm in three planes of space. Measurement reported in mm at each timepoint is the cumulative movement up to that timpoint during the one month of monitoring of tooth movement.
T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary First Molar Movement (Displacement)
Time Frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Magnitude of maxillary first molar tooth movement for every 4-5 days during a one month period. Measurements will be done in mm in three planes of space.
T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary Canine Tooth Movement (Rotation)
Time Frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Magnitude of canine tooth movement for every 4-5 days during a one month period. Measurements will be done in degrees in three planes of space.
T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Tracking Maxillary First Molar Displacement (Rotation)
Time Frame: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).
Magnitude of maxillary first molar tooth movement for every 4-5 days during a one month period. Measurements will be done in degrees in three planes of space.
T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sponsor

The organization or person who initiates the study and who has authority and control over the study.
UConn Health

Investigators

Investigators

A researcher involved in a clinical study. Related terms include site principal investigator, site sub-investigator, study chair, study director, and study principal investigator.
  • Principal Investigator: Flavio Uribe, DDS, UConn Health

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

Study Start

The actual date on which the first participant was enrolled in a clinical study. The "anticipated" study start date is the date that the researchers think will be the study start date.
December 31, 2020

Primary Completion (Actual)

Primary Completion

The date on which the last participant in a clinical study was examined or received an intervention to collect final data for the primary outcome measure. Whether the clinical study ended according to the protocol or was terminated does not affect this date. For clinical studies with more than one primary outcome measure with different completion dates, this term refers to the date on which data collection is completed for all the primary outcome measures. The "anticipated" primary completion date is the date that the researchers think will be the primary completion date for the study.
March 20, 2024

Study Completion (Actual)

Study Completion

The date on which the last participant in a clinical study was examined or received an intervention/treatment to collect final data for the primary outcome measures, secondary outcome measures, and adverse events (that is, the last participant's last visit). The "anticipated" study completion date is the date that the researchers think will be the study completion date.
June 30, 2024

Study Registration Dates

First Submitted

First Submitted

The date on which the study sponsor or investigator first submitted a study record to ClinicalTrials.gov. There is typically a delay of a few days between the first submitted date and the record's availability on ClinicalTrials.gov (the first posted date).
February 28, 2023

First Submitted That Met QC Criteria

First Submitted That Met QC Criteria

The date on which the study sponsor or investigator first submits a study record that is consistent with National Library of Medicine (NLM) quality control (QC) review criteria. The sponsor or investigator may need to revise and submit a study record one or more times before NLM's QC review criteria are met. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
March 9, 2023

First Posted (Actual)

First Posted

The date on which the study record was first available on ClinicalTrials.gov after National Library of Medicine (NLM) quality control (QC) review has concluded. There is typically a delay of a few days between the date the study sponsor or investigator submitted the study record and the first posted date.
March 23, 2023

Study Record Updates

Last Update Posted (Estimated)

Last Update Posted

The most recent date on which changes to a study record were made available on ClinicalTrials.gov. There may be a delay between when the changes were submitted to ClinicalTrials.gov by the study's sponsor or investigator (the last update submitted date) and the last update posted date.
December 17, 2025

Last Update Submitted That Met QC Criteria

Last Update Submitted That Met QC Criteria

The most recent date on which the study sponsor or investigator submitted changes to a study record that are consistent with National Library of Medicine (NLM) quality control (QC) review criteria. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
December 1, 2025

Last Verified

Last Verified

The most recent date on which the study sponsor or investigator confirmed the information about a clinical study on ClinicalTrials.gov as accurate and current. If a study with a recruitment status of recruiting; not yet recruiting; or active, not recruiting has not been confirmed within the past 2 years, the study's recruitment status is shown as unknown.
December 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

Other Study ID Numbers

Identifiers or ID numbers other than the NCT number that are assigned to a clinical study by the study's sponsor, funders, or others. These numbers may include unique identifiers from other trial registries and National Institutes of Health grant numbers.
  • 21-113-2

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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