Patellar Tendon Physiotheraphy Acute Effects Trial (PTPAFT)

January 5, 2026 updated by: Elif Akduran, Dokuz Eylul University

Investigation of the Acute Effects of Different Physiotherapy Methods Applied to the Patellar Tendon: A Single-Blind Randomized Controlled Trial

This randomized controlled trial investigated the acute effects of different physiotherapy interventions applied to the patellar tendon. Participants were randomly assigned to one of four groups: deep friction massage, thermal agent application, quadriceps resistance exercise, or a control group. Each intervention was delivered in a single session. Outcomes of the study included changes in skin temperature, muscle strength, flexibility, and pulse rate. All measurements were taken immediately before the intervention and again immediately after, 15 minutes after, and 60 minutes after the intervention. The study was conducted with healthy adult volunteers. The results of this study are expected to contribute to a better understanding of how different physiotherapy modalities acutely influence the patellar tendon region.

Study Overview

Status

Status

Indicates the current recruitment status or the expanded access status.
Completed

Conditions

Conditions

The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.

Intervention / Treatment

Intervention / Treatment

A process or action that is the focus of a clinical study. Interventions include drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available. Interventions can also include noninvasive approaches, such as education or modifying diet and exercise.

Detailed Description

This study examined the immediate physiological responses of the patellar tendon region following different physiotherapy interventions. Participants were allocated into four groups: (1) deep friction massage applied directly to the patellar tendon, (2) a locally applied superficial thermal agent, (3) a structured quadriceps resistance exercise protocol, and (4) a no-intervention control group. Each intervention was administered as a single session under standardized laboratory conditions.

Outcome measures included skin temperature assessed with thermal imaging, quadriceps muscle strength measured with a handheld dynamometer, flexibility assessed by standardized clinical procedures, and pulse rate. All measurements were collected at four time points: immediately before the intervention, immediately after, 15 minutes after, and 60 minutes after the intervention.

The study was conducted with healthy adult volunteers to evaluate the acute physiological effects of commonly used physiotherapy modalities on the patellar tendon region. The findings are intended to inform clinical decision-making by clarifying how different physiotherapy techniques influence tendon-related parameters within the first hour following treatment.

Study Type

Study Type

Describes the nature of a clinical study. Study types include interventional studies (also called clinical trials), observational studies (including patient registries), and expanded access.
Interventional

Enrollment (Actual)

Enrollment

The number of participants in a clinical study. The "anticipated" enrollment is the target number of participants that the researchers need for the study.
84

Phase

Phase

The stage of a clinical trial studying a drug or biological product, based on definitions developed by the U.S. Food and Drug Administration (FDA). The phase is based on the study's objective, the number of participants, and other characteristics. There are five phases: Early Phase 1 (formerly listed as Phase 0), Phase 1, Phase 2, Phase 3, and Phase 4. Not Applicable is used to describe trials without FDA-defined phases, including trials of devices or behavioral interventions.
  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • balçova
      • Izmir, balçova, Turkey (Türkiye), 35330
        • Dokuz Eylül University, İzmir

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Eligibility Criteria

The key requirements that people who want to participate in a clinical study must meet or the characteristics they must have. Eligibility criteria consist of both inclusion criteria (which are required for a person to participate in the study) and exclusion criteria (which prevent a person from participating). Types of eligibility criteria include whether a study accepts healthy volunteers, has age or age group requirements, or is limited by sex.

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Ages 18 to 24 years
  • Not having engaged in regular exercise training within the past 6 months
  • Body Mass Index (BMI) below 30
  • Ability to complete all assessment procedures
  • Ability to understand the study procedures and provide written informed consent

Exclusion Criteria:

  • Presence of any systemic or musculoskeletal disorder
  • Onset of pain during the assessment procedure
  • History of knee joint or peri-articular injury within the past 6 months
  • Presence of neurological, vascular, or rheumatological disease
  • Any dermatological condition that may affect skin integrity

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm

Participant Group / Arm

A group or subgroup of participants in a clinical trial that receives a specific intervention/treatment, or no intervention, according to the trial's protocol.
Intervention / Treatment

Intervention / Treatment

A process or action that is the focus of a clinical study. Interventions include drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available. Interventions can also include noninvasive approaches, such as education or modifying diet and exercise.
Experimental: Deep Friction Massage
A single session of deep friction massage applied directly to the patellar tendon
Other: Deep Friction Massage
A single session of deep friction massage applied directly to the patellar tendon.
Experimental: Thermal Agent Application
A locally applied superficial thermal agent delivered as a single session.
Other: Thermal Agent Application
A single application of a thermal agent (hot pack) applied to the patellar tendon region.
Experimental: Quadriceps Exercise
A single session of standardized quadriceps resistance exercise protocol.
Other: Quadriceps Exercise
A single session of quadriceps resistance exercise targeting knee extensor muscles.
No Intervention: Control
No treatment administered; participants remained at rest during the session.

What is the study measuring?

Primary Outcome Measures

Primary Outcome Measures

In a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment. Most clinical studies have one primary outcome measure, but some have more than one.
Outcome Measure
Measure Description
Time Frame
Skin Temperature Change
Time Frame: Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Skin temperature of the patellar tendon region measured using infrared thermography at four time points to analyze acute thermal response.
Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Quadirceps Muscle Strength
Time Frame: Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Isometric quadriceps muscle strength measured with a handheld dynamometer at four time points to assess acute changes following intervention.
Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Hamstring and Quadriceps Flexibility
Time Frame: Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Flexibility of the quadriceps and hamstring assessed using a standardized stretching test at four time points to assess evaluate changes.
Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Dorsalis Pedis Pulse Rate
Time Frame: Baseline, immediately after intervention, 15 minutes after, 60 minutes after
Pulse rate measured by palpation at four time points (baseline, immediately after intervention, 15 minutes, and 60 minutes) to evaluate acute cardiovascular response to the intervention.
Baseline, immediately after intervention, 15 minutes after, 60 minutes after

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sponsor

The organization or person who initiates the study and who has authority and control over the study.
Dokuz Eylul University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

Study Start

The actual date on which the first participant was enrolled in a clinical study. The "anticipated" study start date is the date that the researchers think will be the study start date.
April 25, 2025

Primary Completion (Actual)

Primary Completion

The date on which the last participant in a clinical study was examined or received an intervention to collect final data for the primary outcome measure. Whether the clinical study ended according to the protocol or was terminated does not affect this date. For clinical studies with more than one primary outcome measure with different completion dates, this term refers to the date on which data collection is completed for all the primary outcome measures. The "anticipated" primary completion date is the date that the researchers think will be the primary completion date for the study.
June 20, 2025

Study Completion (Actual)

Study Completion

The date on which the last participant in a clinical study was examined or received an intervention/treatment to collect final data for the primary outcome measures, secondary outcome measures, and adverse events (that is, the last participant's last visit). The "anticipated" study completion date is the date that the researchers think will be the study completion date.
December 1, 2025

Study Registration Dates

First Submitted

First Submitted

The date on which the study sponsor or investigator first submitted a study record to ClinicalTrials.gov. There is typically a delay of a few days between the first submitted date and the record's availability on ClinicalTrials.gov (the first posted date).
December 21, 2025

First Submitted That Met QC Criteria

First Submitted That Met QC Criteria

The date on which the study sponsor or investigator first submits a study record that is consistent with National Library of Medicine (NLM) quality control (QC) review criteria. The sponsor or investigator may need to revise and submit a study record one or more times before NLM's QC review criteria are met. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
December 21, 2025

First Posted (Estimated)

First Posted

The date on which the study record was first available on ClinicalTrials.gov after National Library of Medicine (NLM) quality control (QC) review has concluded. There is typically a delay of a few days between the date the study sponsor or investigator submitted the study record and the first posted date.
January 5, 2026

Study Record Updates

Last Update Posted (Actual)

Last Update Posted

The most recent date on which changes to a study record were made available on ClinicalTrials.gov. There may be a delay between when the changes were submitted to ClinicalTrials.gov by the study's sponsor or investigator (the last update submitted date) and the last update posted date.
January 7, 2026

Last Update Submitted That Met QC Criteria

Last Update Submitted That Met QC Criteria

The most recent date on which the study sponsor or investigator submitted changes to a study record that are consistent with National Library of Medicine (NLM) quality control (QC) review criteria. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
January 5, 2026

Last Verified

Last Verified

The most recent date on which the study sponsor or investigator confirmed the information about a clinical study on ClinicalTrials.gov as accurate and current. If a study with a recruitment status of recruiting; not yet recruiting; or active, not recruiting has not been confirmed within the past 2 years, the study's recruitment status is shown as unknown.
January 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

Other Study ID Numbers

Identifiers or ID numbers other than the NCT number that are assigned to a clinical study by the study's sponsor, funders, or others. These numbers may include unique identifiers from other trial registries and National Institutes of Health grant numbers.
  • PTT-2025-DEU

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Patellar Tendon

Clinical Trials on Deep Friction Massage

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Cookie Settings

We use cookies to ensure that we give you the best experience on our website. For more details carefully read our Privacy and Cookies Policy. ...>>>You can change your preferences or withdraw your consent at any time by deleting the cookies from your website or computer as described in the policy. Please accept it and choose your preferences by ticking the corresponding boxes in the "Manage Settings" section below. Please carefully read our Terms of Service before you proceed with using any part of this website.
«Manage Settings