- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00005770
Investigation of the Effect of Acupuncture Needling on Connective Tissue Using Ultrasound Elastography
June 23, 2005 updated by: National Center for Research Resources (NCRR)
During acupuncture treatment, acupuncture needles are inserted and manipulated until a characteristic local tissue reaction termed "de qi" is observed.
De qi can be perceived by the acupuncturist in the form of "needle grasp", a mechanical gripping of the needle by the tissue.
De qi is considered essential to the therapeutic effect of acupuncture.
Therefore, the investigator proposes that understanding this local tissue reaction will lead to an understanding of how the therapeutic effect of acupuncture therapy arises.
Specifically, it is hypothesized that needle manipulation causes winding of collagen and elastic fibers around the needle.
This action induces tension in the collagen network surrounding the needling site and results in a mechanical signal that is transduced into local cells.
The objective of the current work is to use ultrasound elastography, a recently developed ultrasound imaging technique, to visualize and quantify changes in the elastic properties of skin and subcutaneous tissue in 12 healthy human volunteers as a result of acupuncture needle manipulation.
Study Overview
Study Type
Observational
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Vermont
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Burlington, Vermont, United States, 05401
- University of Vermont
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 55 years (Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Healthy
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
June 1, 2000
First Submitted That Met QC Criteria
June 1, 2000
First Posted (Estimate)
June 2, 2000
Study Record Updates
Last Update Posted (Estimate)
June 24, 2005
Last Update Submitted That Met QC Criteria
June 23, 2005
Last Verified
November 1, 2001
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- NCRR-M01RR00109-0745
- M01RR000109 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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