Effect of Avastin in Juxtafoveal Telangiectasias

Does Avastin Change Evolution in Juxtafoveal Telangiectasias?

Sponsors

Lead Sponsor: Asociación para Evitar la Ceguera en México

Source Asociación para Evitar la Ceguera en México
Brief Summary

Evaluation of efficacy of Intravitreal Injection of Bevacizumab in patients with Yuxtafoveal Telangiectasias

Detailed Description

After diagnose Yuxtafoveal telangiectasias secondary to Branch Retinal Vein Occlusion and with Idiopathic Ethiology by clinical signs and Fluorescein angiogram (FA)findings we treated patients with Intravitreal Injection of Bevacizumab (2.5mg/0.1ml). We performed a complete ophthalmological evaluation and at baseline and follow-up (1 and 3 months) we evaluate ETDRS Best Corrected visual acuity (BCVA), fluorescein angiogram (FA) and Optical Coherence Tomography (OCT)findings. We found an improvement in visual acuity and reduction of FA leakage and decrease retinal thickness in OCT.

Overall Status Unknown status
Start Date September 2006
Completion Date November 2006
Phase Phase 3
Study Type Interventional
Primary Outcome
Measure Time Frame
Best corrected Visual Acuity
Fluorescein Angiogram: Leakage
Optical Coherence Tomography: Retinal thickness
Condition
Intervention

Intervention Type: Drug

Intervention Name: Bevacizumab

Intervention Type: Procedure

Intervention Name: Intravitreal injection of Bevacizumab

Eligibility

Criteria:

Inclusion Criteria:

- Patients with Telangiectasias secondary to Branch Retinal Vein Occlusion

- Patients with Idiopathic Juxtafoveal Retinal Telangiectasias

Exclusion Criteria:

- Diabetic Retinopathy and Diabetic Macular Edema

- Hypertensive Retinopathy

- Choroidal Neovascularization

Gender: All

Minimum Age: 40 Years

Maximum Age: 70 Years

Overall Official
Last Name Role Affiliation
Veronica Kon-Jara, MD Principal Investigator Asociación para Evitar la Ceguera en México
Overall Contact

Last Name: Verónica Kon-Jara, MD

Phone: 5510841400

Phone Ext.: 1171-1172

Email: [email protected]

Location
Facility: Status: Contact: Investigator: Asociacion para Evitar la Ceguera en Mexico Veronica Kon-Jara, MD 5510841400 1171-1172 [email protected] Orlando Ustariz-Gonzalez, MD Sub-Investigator Elizabeth Reyna-Castelan, MD Sub-Investigator Nelida Salazar-Teran, MD Sub-Investigator Jans Fromow-Guerra, MD Sub-Investigator Hugo Quiroz-Mercado, MD Sub-Investigator
Location Countries

Mexico

Verification Date

November 2006

Keywords
Has Expanded Access No
Condition Browse
Study Design Info

Allocation: Non-Randomized

Intervention Model: Factorial Assignment

Primary Purpose: Treatment

Masking: None (Open Label)

Source: ClinicalTrials.gov