- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00580268
Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity
August 11, 2014 updated by: Viguera, Adele, Massachusetts General Hospital
The purpose of this study is to examine risk factors for relapse of bipolar disorder during pregnancy and the postpartum period.
The main goal of this study is to find the risks that may make it more likely for a woman with bipolar disorder to experience a depressive, manic, or hypomanic episode during her pregnancy and the postpartum period.
Study Overview
Status
Completed
Study Type
Observational
Enrollment (Actual)
118
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Georgia
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Atlanta, Georgia, United States, 30322
- Emory University
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Massachusetts
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Boston, Massachusetts, United States, 02114
- Massachusetts Geral Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 45 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Sampling Method
Non-Probability Sample
Study Population
psychiatrists, referring obstetricians, community-based health centers, triage, and women who have previously given written permission to be contacted about research studies within the MGH Perinatal and Reproductive Psychiatry Program
Description
Inclusion Criteria:
- medically healthy adult women (ages 18-45) fulfilling DSM-IV criteria for bipolar disorder of any type (1 or 2) who are currently pregnant within 14 weeks gestation dated by last menstrual period;
- euthymic at the time of conception;
- able to give informed consent and comply with study procedures;
- have a treating psychiatrist, physician or mental health clinician. Gravid women between the ages of 18 and 45
Exclusion Criteria:
- active suicidality or homicidality;
- active substance use disorder with 6 months prior to enrollment, or
- positive urine drug screen at enrollment.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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H
Pregnant women with bipolar disorder
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
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psychiatric morbidity
Time Frame: 15 months
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15 months
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Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
obstetrical outcomes
Time Frame: 6 months
|
6 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Adele C Viguera, MD, MGH
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
August 1, 2005
Primary Completion (Actual)
December 1, 2010
Study Completion (Actual)
July 1, 2013
Study Registration Dates
First Submitted
December 20, 2007
First Submitted That Met QC Criteria
December 20, 2007
First Posted (Estimate)
December 24, 2007
Study Record Updates
Last Update Posted (Estimate)
August 12, 2014
Last Update Submitted That Met QC Criteria
August 11, 2014
Last Verified
August 1, 2014
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2005P001167
- R01MH071762 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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