Assessing Depression in a Geriatric Cancer Population

January 12, 2024 updated by: Memorial Sloan Kettering Cancer Center
The goal of this study is to learn more about how we measure depression in elderly cancer patients (patients aged 70 and older). Depression is one of the most common causes of emotional distress in the elderly and continues to be under-recognized. This is a problem because depression can have a negative impact on quality of life. The symptoms of depression are linked to poor health outcomes and higher costs of health care. In fact, depression is one of the top five concerns facing the elderly today.

Study Overview

Status

Active, not recruiting

Conditions

Detailed Description

We have a few questionnaires that have been used to measure depression, but we do not know how these measures work with people with cancer. This study will help us answer this question. To complete this study, we need people who may or may not be feeling down or depressed.

If you choose to take part, you will be asked to do the following:

  1. Fill out questionnaires that ask about:

    • Your age, eduction, race, and income
    • Your mood

    In all, these questionnaires will take about 10 minutes to complete.

  2. Answer questions about your mood. This will also take about 10 minutes to complete.

Study Type

Observational

Enrollment (Actual)

201

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • New York
      • New York, New York, United States, 10065
        • Memorial Sloan Kettering Cancer Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

70 years and older (Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Geriatric Patients with Breast or Prostate Cancer

Description

Inclusion Criteria:

  1. Age 70 and older
  2. Diagnosis of early or late stage prostate cancer, or diagnosis of early or late stage breast cancer
  3. Actively engaged in one of the following cancer treatments: chemotherapy, radiation therapy, hormone therapy
  4. Able to provide informed consent
  5. Ability to converse, write and read English

Exclusion Criteria:

1.Major psychopathology or cognitive impairment likely in the judgment of the research staff to interfere with the participation or completion of the protocol.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
1
150 patients will be women with breast cancer (75 early stage and 75 late stage)
2
150 will be men with prostate cancer (75 early stage and 75 late stage)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Test the sensitivity and specificity of the Geriatric Depression Scale-Short Form and two other widely used assessments of depression to detect major and minor depression in a geriatric breast and prostate cancer population.
Time Frame: 2 years
2 years

Secondary Outcome Measures

Outcome Measure
Time Frame
To develop a cut-off score for the GDS that is specific to a cancer population.
Time Frame: 2 years
2 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Memorial Sloan Kettering Cancer Center

Collaborators

City of Hope National Medical Center

Investigators

  • Principal Investigator: Christian Nelson, Ph.D., Memorial Sloan Kettering Cancer Center

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2006

Primary Completion (Estimated)

June 10, 2025

Study Completion (Estimated)

June 10, 2025

Study Registration Dates

First Submitted

December 19, 2007

First Submitted That Met QC Criteria

December 19, 2007

First Posted (Estimated)

December 24, 2007

Study Record Updates

Last Update Posted (Actual)

January 16, 2024

Last Update Submitted That Met QC Criteria

January 12, 2024

Last Verified

January 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 06-100

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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