- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00786630
Intervention to Reduce Injection Drug Use
December 19, 2014 updated by: University of Colorado, Denver
This is a five-year prospective randomized trial comparing two intervention conditions designed to facilitate substance abuse treatment entry and enhance retention in order to reduce the behaviors associated with HIV and HCV risk among injection drug users (IDUs) and to improve client overall functioning.
The overall goal of this project is to compare strengths-based case-management (CM) to an enhanced version of CM that uses case managers to facilitate a therapeutic alliance (CM/FTA) among out-of-treatment IDUs in Denver.
Study Overview
Status
Completed
Conditions
Study Type
Interventional
Enrollment (Actual)
726
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Colorado
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Denver, Colorado, United States, 80205
- Project Safe
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- opiate injection at least 3 times a week during the last 6-months
- 18 years of age or older
- no drug abuse treatment in the 30-days prior to the interview
- not transient
- no known reason (e.g. pending jail time) why they will not be available for follow-up interviews
- not involved in Project Safe research activities in the previous 12 months
- willing to meet with an Addiction Research and Treatment Services (methadone clinic) counselor
- eligible to be treated at ARTS
Exclusion Criteria:
- too intoxicated or impaired mentally to voluntarily consent to participate in the project and/or respond to the interview
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Case Management
|
Clients will receive counseling and/or referrals for help with nine life domains (life skills, finances, leisure activities, relationships, living arrangements, occupation/education, health, mental health, recovery from substances, legal assistance) for a period of five months after baseline.
|
Experimental: Facilitated Treatment Alliance
|
Clients will receive counseling and/or referrals for help with nine life domains (life skills, finances, leisure activities, relationships, living arrangements, occupation/education, health, mental health, recovery from substances, legal assistance) for a period of five months after baseline.
They will also receive a facilitated treatment alliance, which consists of meetings with methadone counselors to aid in treatment entry.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Treatment entry and retention
Time Frame: Baseline, 6 months after baseline, 12 months after baseline
|
Baseline, 6 months after baseline, 12 months after baseline
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Drug injection and HIV/HCV risk behaviors
Time Frame: Baseline, 6 months after baseline, 12 months after baseline
|
Baseline, 6 months after baseline, 12 months after baseline
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Robert E. Booth, Ph.D., University of Colorado, Denver
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
November 1, 2007
Primary Completion (Actual)
December 1, 2012
Study Completion (Actual)
February 1, 2013
Study Registration Dates
First Submitted
November 4, 2008
First Submitted That Met QC Criteria
November 5, 2008
First Posted (Estimate)
November 6, 2008
Study Record Updates
Last Update Posted (Estimate)
December 23, 2014
Last Update Submitted That Met QC Criteria
December 19, 2014
Last Verified
December 1, 2014
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 06-1131
- 2R01DA009832-11 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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