Magnetic Prefrontal Stimulation for Studying the Role of the Cortex in High-level Cognition Processes and Reward System

April 20, 2015 updated by: Moshe Isserles, Hadassah Medical Organization
The investigators intend to study the role of the cortex in high- level cognition processes and sensory adaptation, by the use of non-invasive Transcranial Magnetic stimulation and various cognitive tests.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

91

Phase

  • Early Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Israel
      • Jerusalem, Israel
        • Hadassah medical org

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 60 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • healthy men and women, age of 18-60
  • answered negatively to questions of TMS safety questionnaire
  • signed and declared about their agreement to participate in the study
  • hebrew speaker

Exclusion Criteria:

  • self history of significant mental disorder
  • self history or first-degree relatives history of epilepsy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Single Group Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: LT PFC HIGH FREQ TMS
Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Active Comparator: LT PFC LOW FREQ TMS
Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Active Comparator: RT PFC HIGH FREQ TMS
Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Active Comparator: RT PFC LOW FREQ TMS
Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Sham Comparator: SHAM STIMULATION
Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Changes in scoring of different tests and questionnaires
Time Frame: One year
One year

Secondary Outcome Measures

Outcome Measure
Time Frame
Correlation of different tests and questionnaires
Time Frame: One year
One year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hadassah Medical Organization

Collaborators

Ben-Gurion University of the Negev

Investigators

  • Principal Investigator: Moshe Isserles, Dr., Hadassa Medical Organization

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

June 1, 2009

Primary Completion (Actual)

June 1, 2014

Study Completion (Actual)

June 1, 2014

Study Registration Dates

First Submitted

June 2, 2009

First Submitted That Met QC Criteria

June 2, 2009

First Posted (Estimate)

June 3, 2009

Study Record Updates

Last Update Posted (Estimate)

April 22, 2015

Last Update Submitted That Met QC Criteria

April 20, 2015

Last Verified

April 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 0116-09-HMO-CTIL

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Healthy Volunteers

Clinical Trials on TMS

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe