Quality of Life and Treatment Satisfaction of People With Type 2 Diabetes: A European Survey (PANORAMA)

The present European survey seeks to assess quality of life and satisfaction with treatment in people with T2DM and to appreciate disease and treatment variables including hypoglycaemia and level of glycaemic control. It will also provide relevant information on other important aspects such as the level of correlation of objective measures such as HbA1c with health status, QoL and satisfaction with current treatment. Overall 5000 randomly selected patients will be invited to participate from a representative sample of clinical practices during a pre-specified period. The study will entail a single patient visit. Patients who agree to the study and give their informed consent will complete questionnaires which, combined with retrospective notes review & an HbA1c test, will allow patient, disease and treatment variables to be collected. An HbA1c test is a finger prick test to measure glycosylated haemoglobin in the blood indicating the level of blood glucose over the last 8-12 weeks.

Study Overview

• Status: Completed
• Conditions: Diabetes

• Study Type: Observational
• Enrollment (Actual): 5926

Contacts and Locations

Study Locations

• France
  • Antibes, France
    • Research Site
  • Athies, France
    • Research Site
  • Audruicq, France
    • Research Site
  • Auxerre, France
    • Research Site
  • Baigneux les Juifs, France
    • Research Site
  • Baume les Dames, France
    • Research Site
  • Beaumont sur leze, France
    • Research Site
  • Beaurepaire, France
    • Research Site
  • Beauvais, France
    • Research Site
  • Berat, France
    • Research Site
  • Bettacourt la Ferree, France
    • Research Site
  • Beziers, France
    • Research Site
  • Bezons, France
    • Research Site
  • Blois, France
    • Research Site
  • Boulogne sur Gesse, France
    • Research Site
  • Bresles, France
    • Research Site
  • Brest Cedex 3, France
    • Research Site
  • Breteuil Sur Iton, France
    • Research Site
  • Bruere Allichamps, France
    • Research Site
  • Bulles, France
    • Research Site
  • Burry, France
    • Research Site
  • Cany Barville, France
    • Research Site
  • Capdenac Gare, France
    • Research Site
  • Cappelle Brouck, France
    • Research Site
  • Carquefou, France
    • Research Site
  • Carresse Cassaber, France
    • Research Site
  • Carros, France
    • Research Site
  • Celles sur Plaine, France
    • Research Site
  • Chabons, France
    • Research Site
  • Champagnole, France
    • Research Site
  • Champigny Sur Marne, France
    • Research Site
  • Chanmpdeniers St Denis, France
    • Research Site
  • Chartrettes, France
    • Research Site
  • Chatillon sur Colmont, France
    • Research Site
  • Chauvigny, France
    • Research Site
  • Clairac, France
    • Research Site
  • Clichy, France
    • Research Site
  • Comps, France
    • Research Site
  • Concarneu, France
    • Research Site
  • Courbevoie, France
    • Research Site
  • Courpiere, France
    • Research Site
  • Coutances, France
    • Research Site
  • Coutouvre, France
    • Research Site
  • Dambach La Ville, France
    • Research Site
  • Dieulouard, France
    • Research Site
  • Digoin, France
    • Research Site
  • Donges, France
    • Research Site
  • Douchy Les Mines, France
    • Research Site
  • Drap, France
    • Research Site
  • Equeurdreville Hainneville, France
    • Research Site
  • Escaudain, France
    • Research Site
  • Faverges, France
    • Research Site
  • Fenouillet, France
    • Research Site
  • Firmi, France
    • Research Site
  • Francoville la Garenne, France
    • Research Site
  • Fruges, France
    • Research Site
  • Gelles, France
    • Research Site
  • Gondrecourt le Chateau, France
    • Research Site
  • Guitalens L' Albarede, France
    • Research Site
  • Hanvec, France
    • Research Site
  • Houilles, France
    • Research Site
  • Hyeres, France
    • Research Site
  • Ivry Sur Seine, France
    • Research Site
  • Jussey, France
    • Research Site
  • L' Hay Les Roses, France
    • Research Site
  • La Courneuve, France
    • Research Site
  • La Crau, France
    • Research Site
  • La Ferte st Aubin, France
    • Research Site
  • La Mulatiere, France
    • Research Site
  • La Tranche sur Mer, France
    • Research Site
  • Lamagistere, France
    • Research Site
  • Lanouaille, France
    • Research Site
  • Laroquebrou, France
    • Research Site
  • Lathus st Remy, France
    • Research Site
  • Le Cannet, France
    • Research Site
  • Le Grand Lemps, France
    • Research Site
  • Le Havre, France
    • Research Site
  • Le Monastier sur Gazeille, France
    • Research Site
  • Le Nouvion en Thierache, France
    • Research Site
  • Le Pertre, France
    • Research Site
  • Le Plessis Trevise, France
    • Research Site
  • Le Pontet, France
    • Research Site
  • Les Mees, France
    • Research Site
  • Leyme, France
    • Research Site
  • Lezignan Corbieres, France
    • Research Site
  • Locmiquelic, France
    • Research Site
  • Luneray, France
    • Research Site
  • Lyon, France
    • Research Site
  • Magland, France
    • Research Site
  • Maintenon, France
    • Research Site
  • Mantes La Ville, France
    • Research Site
  • Marcq en Baroeul, France
    • Research Site
  • Marles les Mines, France
    • Research Site
  • Marseille, France
    • Research Site
  • Mauleon Soule, France
    • Research Site
  • Mayet, France
    • Research Site
  • Meximieux, France
    • Research Site
  • Mezzavia, France
    • Research Site
  • Miramas, France
    • Research Site
  • Monce en Berlin, France
    • Research Site
  • Montelimar, France
    • Research Site
  • Montfort en Chalosse, France
    • Research Site
  • Montoire Sur le Loir, France
    • Research Site
  • Montreuil, France
    • Research Site
  • Monts sur Guesnes, France
    • Research Site
  • Mussidan, France
    • Research Site
  • Narbonne, France
    • Research Site
  • Neuilly Les Dijon, France
    • Research Site
  • Nice, France
    • Research Site
  • Niederschaeffolsheim, France
    • Research Site
  • Noisy Le Sec, France
    • Research Site
  • Nordausques, France
    • Research Site
  • Nouatre, France
    • Research Site
  • Oberhausbergen, France
    • Research Site
  • Orchies, France
    • Research Site
  • Orlienas, France
    • Research Site
  • Ormes, France
    • Research Site
  • Pantin, France
    • Research Site
  • Paris, France
    • Research Site
  • Pau, France
    • Research Site
  • Pauillac, France
    • Research Site
  • Pernes les Fontaines, France
    • Research Site
  • Pibrac, France
    • Research Site
  • Pierrepont sur Avre, France
    • Research Site
  • Pitgam, France
    • Research Site
  • Plancoet, France
    • Research Site
  • Pleneuf val Andre, France
    • Research Site
  • Plouvorn, France
    • Research Site
  • Pornic, France
    • Research Site
  • Port La Nouvelle, France
    • Research Site
  • Pradines, France
    • Research Site
  • Puilley Les Vignes, France
    • Research Site
  • Puttelange aux Lacs, France
    • Research Site
  • Quessoy, France
    • Research Site
  • Quiberon, France
    • Research Site
  • Quimper, France
    • Research Site
  • Rambervillers, France
    • Research Site
  • Renaze, France
    • Research Site
  • Richemont, France
    • Research Site
  • Robion, France
    • Research Site
  • Romainville, France
    • Research Site
  • Rombas, France
    • Research Site
  • Romorantin Lanthenay, France
    • Research Site
  • Salles, France
    • Research Site
  • Salome, France
    • Research Site
  • Sassenage, France
    • Research Site
  • Sault les Rethel, France
    • Research Site
  • Soissons, France
    • Research Site
  • Soisy sur Ecole, France
    • Research Site
  • Soyaux, France
    • Research Site
  • St Andre de Sangonis, France
    • Research Site
  • St Aubin des Chateaux, France
    • Research Site
  • St Bonnet le Chateau, France
    • Research Site
  • St Jean de Maurienne, France
    • Research Site
  • St Laurent d Aigouze, France
    • Research Site
  • St Martin des Champs, France
    • Research Site
  • St Saens, France
    • Research Site
  • St Thuriau, France
    • Research Site
  • St Yorre, France
    • Research Site
  • Ste Menehould, France
    • Research Site
  • Strasbourg, France
    • Research Site
  • Thann, France
    • Research Site
  • Thure, France
    • Research Site
  • Toufflers, France
    • Research Site
  • Toulon, France
    • Research Site
  • Tourcoing, France
    • Research Site
  • Troyes, France
    • Research Site
  • Uzes, France
    • Research Site
  • Vailly Sur Aisne, France
    • Research Site
  • Valenton, France
    • Research Site
  • Valras Plage, France
    • Research Site
  • Vaugneray, France
    • Research Site
  • Villefagnan, France
    • Research Site
  • Villejuif, France
    • Research Site
  • Villeurbanne, France
    • Research Site
  • Vitry Le Francois, France
    • Research Site
• Germany
  • Aachen, Germany
    • Research Site
  • Alsdorf, Germany
    • Research Site
  • Ampfing, Germany
    • Research Site
  • Aschersleben, Germany
    • Research Site
  • Augsburg, Germany
    • Research Site
  • Bad Freienwalde, Germany
    • Research Site
  • Bad Staffelstein, Germany
    • Research Site
  • Berlin, Germany
    • Research Site
  • Biberbach, Germany
    • Research Site
  • Bonn, Germany
    • Research Site
  • Coburg, Germany
    • Research Site
  • Duisburg, Germany
    • Research Site
  • Edenkoben, Germany
    • Research Site
  • Erfurt, Germany
    • Research Site
  • Eschweiler, Germany
    • Research Site
  • Essen, Germany
    • Research Site
  • Frechen, Germany
    • Research Site
  • Fuchsstadt, Germany
    • Research Site
  • Fulda, Germany
    • Research Site
  • G�ntersleben, Germany
    • Research Site
  • Hamburg, Germany
    • Research Site
  • Heinsberg, Germany
    • Research Site
  • Holzkirchen, Germany
    • Research Site
  • Homburg, Germany
    • Research Site
  • Iserlohn, Germany
    • Research Site
  • Kaisersesch, Germany
    • Research Site
  • Kalkar, Germany
    • Research Site
  • Kehl, Germany
    • Research Site
  • Kirchheim, Germany
    • Research Site
  • Klingenberg, Germany
    • Research Site
  • Ludwigshafen, Germany
    • Research Site
  • Magdeburg, Germany
    • Research Site
  • Marpingen, Germany
    • Research Site
  • Moers, Germany
    • Research Site
  • Munchen, Germany
    • Research Site
  • Nurnberg, Germany
    • Research Site
  • Oberursel, Germany
    • Research Site
  • Pretzfeld, Germany
    • Research Site
  • Reit im Winkl, Germany
    • Research Site
  • Rimbach, Germany
    • Research Site
  • Sand, Germany
    • Research Site
  • Schwaig, Germany
    • Research Site
  • Sinntal, Germany
    • Research Site
  • Sonthofen, Germany
    • Research Site
  • Westerkappeln, Germany
    • Research Site
  • Wiesbaden, Germany
    • Research Site
  • Zweibrucken, Germany
    • Research Site
  • Zwenkau, Germany
    • Research Site
• Greece
  • Athens, Greece
    • Research Site
• Ireland
  • Belfast, Ireland
    • Research Site
  • Co. ANRTIM, Ireland
    • Research Site
• Italy
  • Latina, Italy
    • Research Site
  • Rome, Italy
    • Research Site
  • Viterbo, Italy
    • Research Site
  • Bari
    • Andria, Bari, Italy
      • Research Site
• Netherlands
  • Drenthe
    • Beilen, Drenthe, Netherlands
      • Research Site
    • Coevorden, Drenthe, Netherlands
      • Research Site
    • Zwartemeer, Drenthe, Netherlands
      • Research Site
  • Flevoland
    • Almere, Flevoland, Netherlands
      • Research Site
  • Friesland
    • Drachten, Friesland, Netherlands
      • Research Site
  • Gelderland
    • Lichtenvoorde, Gelderland, Netherlands
      • Research Site
    • Nijmegen, Gelderland, Netherlands
      • Research Site
  • Groningen
    • Onstwedde, Groningen, Netherlands
      • Research Site
  • Limburg
    • Maastricht, Limburg, Netherlands
      • Research Site
    • Vlodorp, Limburg, Netherlands
      • Research Site
  • Noord-Braband
    • Beek en Donk, Noord-Braband, Netherlands
      • Research Site
    • Den Bosch, Noord-Braband, Netherlands
      • Research Site
    • Etten-Leur, Noord-Braband, Netherlands
      • Research Site
    • Lieshout, Noord-Braband, Netherlands
      • Research Site
    • Schijndel, Noord-Braband, Netherlands
      • Research Site
    • Soerendonk, Noord-Braband, Netherlands
      • Research Site
  • Noord-Holland
    • Edam, Noord-Holland, Netherlands
      • Research Site
    • Hoogwoud, Noord-Holland, Netherlands
      • Research Site
    • Huizen, Noord-Holland, Netherlands
      • Research Site
    • Volendam, Noord-Holland, Netherlands
      • Research Site
  • Overijssel
    • Ermelo, Overijssel, Netherlands
      • Research Site
    • Heeten, Overijssel, Netherlands
      • Research Site
    • Hengelo, Overijssel, Netherlands
      • Research Site
    • Nijverdal, Overijssel, Netherlands
      • Research Site
    • Tubbergen, Overijssel, Netherlands
      • Research Site
  • Utrecht
    • Amersfoort, Utrecht, Netherlands
      • Research Site
  • Zeeland
    • Poortvliet, Zeeland, Netherlands
      • Research Site
  • Zuid-Holland
    • Bennebroek, Zuid-Holland, Netherlands
      • Research Site
    • Den Haag, Zuid-Holland, Netherlands
      • Research Site
    • Dordrecht, Zuid-Holland, Netherlands
      • Research Site
    • Lisse, Zuid-Holland, Netherlands
      • Research Site
    • Rijswijk, Zuid-Holland, Netherlands
      • Research Site
    • Roelofarendsveen, Zuid-Holland, Netherlands
      • Research Site
    • Rotterdam, Zuid-Holland, Netherlands
      • Research Site
    • Spijkernisse, Zuid-Holland, Netherlands
      • Research Site
    • Woerden, Zuid-Holland, Netherlands
      • Research Site
• Spain
  • Madrid, Spain
    • Research Site
  • Andalucia
    • Cadiz, Andalucia, Spain
      • Research Site
  • Cantabria
    • Santander, Cantabria, Spain
      • Research Site
  • Castilla Y Leon
    • Burgos, Castilla Y Leon, Spain
      • Research Site
  • Cataluna
    • Manresa, Cataluna, Spain
      • Research Site
  • Catalu�a
    • Barcelona, Catalu�a, Spain
      • Research Site
  • Comunidad Valenciana
    • Elche, Comunidad Valenciana, Spain
      • Research Site
  • Galicia
    • Pontevedra, Galicia, Spain
      • Research Site
  • Las Palmas De Gran Canaria
    • Gran Canaria, Las Palmas De Gran Canaria, Spain
      • Research Site
  • Madrid
    • Coslada, Madrid, Spain
      • Research Site
    • Fuenlabrada, Madrid, Spain
      • Research Site
• United Kingdom
  • Bath, United Kingdom
    • Research Site
  • Bedford, United Kingdom
    • Research Site
  • Birmingham, United Kingdom
    • Research Site
  • Blackburn, United Kingdom
    • Research Site
  • Blackpool, United Kingdom
    • Research Site
  • Bristol, United Kingdom
    • Research Site
  • Bury St Edmunds, United Kingdom
    • Research Site
  • Cambridge, United Kingdom
    • Research Site
  • Canterbury, United Kingdom
    • Research Site
  • Cardiff, United Kingdom
    • Research Site
  • Cornwall, United Kingdom
    • Research Site
  • Coventry, United Kingdom
    • Research Site
  • Darlington, United Kingdom
    • Research Site
  • Glasgow, United Kingdom
    • Research Site
  • Guildford, United Kingdom
    • Research Site
  • London, United Kingdom
    • Research Site
  • Manchester, United Kingdom
    • Research Site
  • Newcastle, United Kingdom
    • Research Site
  • Penzance, United Kingdom
    • Research Site
  • Plymouth, United Kingdom
    • Research Site
  • Reading, United Kingdom
    • Research Site
  • Salisbury, United Kingdom
    • Research Site
  • Sheffield, United Kingdom
    • Research Site
  • St Albans, United Kingdom
    • Research Site

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

To be recruited in Primary Care Centres mainly, but hospitals will be allowed in some countries

Description

Inclusion Criteria:

• With T2DM, diagnosed at least 1 year prior to entry in the study
• Currently treated with diet, OAD(s) and/or insulin with no change in the type of OAD(s) or insulin in the previous three months

Exclusion Criteria:

• Type 1 diabetes and/or history of diabetic ketoacidosis
• Secondary diabetes (including disease of the exocrine pancreas, endocrinopathies or drug-induced)
• Treatment with systemic glucocorticoids other than replacement therapy. Inhaled, local injected and topical use of glucocorticoids is allowed

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
1; Patients ³ 40 years old, with T2DM diagnosed and followed up in the participating site at least 1 year prior to entry in the study, treated with diet, OADs and/or insulin for at least the past three months

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Diabetes-related QoL and treatment satisfaction questionnaires: DTSQ, ADDQoL, HFSws and EQ5D	Cross-sectional and retrospective

Secondary Outcome Measures

Outcome Measure	Time Frame
Disease-related variables: Years with diabetes, use of SMBG and frequency of monitoring, Hypoglycaemic episodes, Past Medical History, Macro and micro-vascular complications	Retrospective (previous 24 months)
Health-economic variables: Use of healthcare resources Days off work (for either hypoglycaemias, acute or chronic complications)	Retrospective (previous 24 months)

Collaborators and Investigators

• Sponsor: AstraZeneca
• Investigators: Study Director: Angeles Porta, Medical Department.AstraZeneca Spain

Publications and helpful links

General Publications

• Bradley C, Eschwege E, de Pablos-Velasco P, Parhofer KG, Simon D, Vandenberghe H, Gonder-Frederick L. Predictors of Quality of Life and Other Patient-Reported Outcomes in the PANORAMA Multinational Study of People With Type 2 Diabetes. Diabetes Care. 2018 Feb;41(2):267-276. doi: 10.2337/dc16-2655. Epub 2017 Nov 28.
• Simon D, de Pablos-Velasco P, Parhofer KG, Gonder-Frederick L, Duprat Lomon I, Vandenberghe H, Eschwege E, Bradley C. Hypoglycaemic episodes in patients with type 2 diabetes--risk factors and associations with patient-reported outcomes: The PANORAMA Study. Diabetes Metab. 2015 Dec;41(6):470-9. doi: 10.1016/j.diabet.2015.08.007. Epub 2015 Oct 9.
• de Pablos-Velasco P, Parhofer KG, Bradley C, Eschwege E, Gonder-Frederick L, Maheux P, Wood I, Simon D. Current level of glycaemic control and its associated factors in patients with type 2 diabetes across Europe: data from the PANORAMA study. Clin Endocrinol (Oxf). 2014 Jan;80(1):47-56. doi: 10.1111/cen.12119. Epub 2013 May 6.
• Bradley C, de Pablos-Velasco P, Parhofer KG, Eschwege E, Gonder-Frederick L, Simon D. PANORAMA: a European study to evaluate quality of life and treatment satisfaction in patients with type-2 diabetes mellitus--study design. Prim Care Diabetes. 2011 Dec;5(4):231-9. doi: 10.1016/j.pcd.2011.04.004. Epub 2011 Jul 14.

Study record dates

Study Major Dates

• Study Start: May 1, 2009
• Primary Completion (Actual): March 1, 2010
• Study Completion (Actual): March 1, 2010

Study Registration Dates

• First Submitted: June 5, 2009
• First Submitted That Met QC Criteria: June 8, 2009
• First Posted (Estimate): June 9, 2009

Study Record Updates

• Last Update Posted (Estimate): April 27, 2010
• Last Update Submitted That Met QC Criteria: April 26, 2010
• Last Verified: April 1, 2010

More Information

Terms related to this study

• Keywords: Diabetes; Quality of Life; Treatment Satisfaction; HbA1c levels and goals; Healthcare resources consumption
• Additional Relevant MeSH Terms: Glucose Metabolism Disorders; Metabolic Diseases; Endocrine System Diseases; Diabetes Mellitus
• Other Study ID Numbers: NIS-CEU-DUM-2008/2