Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis

October 24, 2016 updated by: Simo Saarakkala, University of Oulu

Comparison Between Intra-articular Ultrasound Imaging, Non-invasive Ultrasound Imaging, Quantitative MRI Imaging, Contrast-enhanced CT Imaging and Arthroscopy for Diagnostics of Knee Osteoarthritis

The purpose of this study is to clarify the potential of intra-articular ultrasound imaging, non-invasive ultrasound imaging, quantitative MRI imaging, contrast-enhanced CT imaging and arthroscopy for diagnostics of knee osteoarthritis. All methods will be cross-correlated and compared with the arthroscopic findings.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

12

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Finland
      • Oulu, Finland, FI-90029
        • Oulu University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients will be selected from those referred to an arthroscopy because of pain symptoms in the knee.

Description

Inclusion Criteria:

  • Kellgren-Lawrence grade = 1-3 or cartilage defect detected in MRI
  • Age >= 20 years

Exclusion Criteria:

  • Tumor or inflammation in the knee
  • Severe general diseases
  • Diabetes

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Knee pain
Group with knee pain problems referred to an arthroscopy.
Other: Intra-articular ultrasound imaging of knee joint during arthroscopy
Other: Non-invasive ultrasound imaging of knee
Other: Quantitative MRI imaging of knee
Other: Contrast-enhanced CT imaging of knee

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Arthroscopical OA grade
Time Frame: 2014
2014

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Oulu

Collaborators

Oulu University Hospital
Kuopio University Hospital
University of Eastern Finland

Investigators

  • Principal Investigator: Simo Saarakkala, Ph.D., University of Oulu and Oulu University Hospital
  • Study Director: Petri Lehenkari, M.D., Ph.D., University of Oulu and Oulu University Hospital
  • Study Director: Miika T Nieminen, Ph.D., University of Oulu and Oulu University Hospital
  • Study Director: Risto Ojala, M.D., Ph.D., Oulu University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2011

Primary Completion (Actual)

April 1, 2014

Study Completion (Actual)

May 1, 2014

Study Registration Dates

First Submitted

May 22, 2011

First Submitted That Met QC Criteria

May 22, 2011

First Posted (Estimate)

May 24, 2011

Study Record Updates

Last Update Posted (Estimate)

October 26, 2016

Last Update Submitted That Met QC Criteria

October 24, 2016

Last Verified

October 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • UltraRusto

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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