Changes in the Permeability of the Blood Brain Barrier and Intestinal Barrier in Humans During Conditions of Stress and Immune Activation: in Vivo Studies
August 15, 2011 updated by: National University Hospital, Singapore
The relevance of BBB and IB permeability changes as a major precipitating cause for cognitive and digestive dysfunction in the military stress setting.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
16 years to 48 years (Adult)
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
Male
Sampling Method
Probability Sample
Study Population
Healthy male troops during combat training
Description
Inclusion Criteria:
- Healthy male troops (aged 18-50 yrs) scheduled to be engaged in a protracted multi-day stressful field exercises.
Exclusion Criteria:
- Significantly systemic disease, including cardiovascular, psychiatric, neurological (including polyneuropathies) and endocrine disease including diabetes mellitus.
- No written informed consent obtained from subject.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Prospective
Cohorts and Interventions
Group / Cohort |
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with combat training stress
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without combat training stress
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
August 15, 2011
First Submitted That Met QC Criteria
August 15, 2011
First Posted (Estimate)
August 16, 2011
Study Record Updates
Last Update Posted (Estimate)
August 16, 2011
Last Update Submitted That Met QC Criteria
August 15, 2011
Last Verified
February 1, 2009
More Information
Terms related to this study
Other Study ID Numbers
- C/08/236
- DSOCL08210 (Other Grant/Funding Number: DSTA Singapore)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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