Akershus Cardiac Examination (ACE) 1950 Study (ACE1950)

December 18, 2022 updated by: Vestre Viken Hospital Trust

Akershus Cardiac Examination 1950 Study - a Cohort Study on Cardio- and Cerebrovascular Disease in 62-65-year-old Subjects

Akershus Cardiac Examination (ACE) 1950 Study is a large, observational, prospective, longitudinal, population-based cohort study. The overall aim is to establish an extensive cardio- and cerebrovascular age cohort of elderly subjects for various longitudinal long-term follow-up studies of cardiovascular and cerebrovascular disease.

Study Overview

Status

Active, not recruiting

Conditions

Detailed Description

Design: The Akershus Cardiac Examination (ACE) 1950 Study is a population-based, prospective, cerebro- and cardiovascular age-cohort study of all men and women born in 1950 in Akershus County, Norway.

Time schedule: Study inclusion and baseline examinations took place in the period September 2012 - May 2015. Follow-up and sub-studies are ongoing.

Current status: As per May 2018, follow-up and sub-studies are ongoing.

Study Type

Observational

Enrollment (Anticipated)

3706

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Norway
    • Akershus
      • Lørenskog, Akershus, Norway, 1478
        • Akershus University Hospital
      • Sandvika, Akershus, Norway, 3004
        • Vestre Viken HT, Baerum Hospital, Department of Medical Research

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years to 63 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Residents of Akershus County, Norway, born in 1950.

Description

Inclusion Criteria:

  • Resident in Akershus County (as per October 2011, prior to study invitation)
  • Born in the year of 1950
  • Ability to consent to participation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
No treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Outcomes related to CVD and CV-associated conditions
Time Frame: Maximum 35 years
Maximum 35 years

Secondary Outcome Measures

Outcome Measure
Time Frame
Specific CV endpoints; e.g. acute myocardial infarction, heart failure, atrial fibrillation, etc.
Time Frame: Maximum 35 years
Maximum 35 years
Specific CV-associated conditions, including renal, cerebrovascular, pulmonary, etc.
Time Frame: Maximum 35 years
Maximum 35 years
Specific clinical phenotypes; e.g. myocardial and arterial structure and function, lung function, etc.
Time Frame: Maximum 35 years
Maximum 35 years

Other Outcome Measures

Outcome Measure
Time Frame
Impact of left atrial size and function measurements by echocardiography on stroke risk in an 62-65-year-old cohort
Time Frame: Within 35 years
Within 35 years
Relation between cognitive function and sub-clinical CVD in a 62-65-year-old Norwegian population cohort
Time Frame: Maximum 35 years
Maximum 35 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Vestre Viken Hospital Trust

Collaborators

University Hospital, Akershus

Investigators

  • Study Director: Arnljot Tveit, MD, PhD, Vestre Viken Hospital Trust, Department of Medical Research
  • Study Director: Helge Røsjø, MD, PhD, University Hospital, Akershus
  • Principal Investigator: Trygve Berge - member of steering committee, MD, Vestre Viken Hospital Trust, Department of Medical Research
  • Principal Investigator: Pål Smith - member of steering committee, MD, PhD, University Hospital, Akershus
  • Principal Investigator: Kjetil Steine - member of steering committee, MD, PhD, University Hospital, Akershus
  • Principal Investigator: Torbjørn Omland - member of steering committee, MD, PhD, University Hospital, Akershus
  • Principal Investigator: Magnus N Lyngbakken - member of steering committee, MD, University Hospital, Akershus

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 1, 2012

Primary Completion (Anticipated)

December 1, 2050

Study Completion (Anticipated)

December 1, 2050

Study Registration Dates

First Submitted

March 13, 2012

First Submitted That Met QC Criteria

March 13, 2012

First Posted (Estimate)

March 15, 2012

Study Record Updates

Last Update Posted (Estimate)

December 20, 2022

Last Update Submitted That Met QC Criteria

December 18, 2022

Last Verified

December 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2011/1475 C
  • AFIA (initial study name) (Other Identifier: Vestre Viken Hospital Trust and Akershus University Hospital)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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