Management of Prostate Cancer in Central China

Comparisons of Management and Outcome of Prostate Cancer in Central China Between 2003 and 2008: A Multi-institutional Report

Some recent reports indicate that incidence of prostate cancer is increasing rapidly in China. However, no large-scale survey of prostate cancer has been done in central China, few data are available regarding its management. The investigators aimed to analyze the management of prostate cancer and compare the outcome of patients with such a survey.

The investigators collected data of patients diagnosed with prostate cancer from the 2003 and 2008 in central China. Data were disaggregated by rural and urban hukou. The survival rate of patients was analyzed using Kaplan-Meier method. Prognostic factors were analyzed using the log-rank test and Cox proportional hazards model.

Study Overview

• Status: Completed
• Conditions: Prostate Cancer

• Study Type: Observational
• Enrollment (Actual): 789

Contacts and Locations

Study Locations

• China
  • Henan
    • Zhengzhou, Henan, China, 450052
      • The First Affiliated Hospital of Zhengzhou University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

• Sampling Method: Probability Sample

Study Population

all inpatients with prostate cancer in 14 hospitals

Description

Inclusion Criteria:

• patients with newly diagnosed prostate cancer were included in the study. Exclusion Criteria:
• Those with a history of prostate cancer who were treated for another disease were excluded from study.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

all patients; We selected 9 cities (Zhengzhou, Luoyang, Kaifeng, Anyang, Xinyang, Zhoukou, Shangqiu, Nanyang, Zhumadian) by probability proportional to size sampling from geographical regions in central China. All cases with complete follow-up data of histological-proven prostate cancer treated in 2003 and 2008 at 14 department of urology in the 9 cities were retrospectively collected. Only patients with newly diagnosed prostate cancer were included in the study. Those with a history of prostate cancer who were treated for another disease were excluded from study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
overall survival	overall survival that was defined as the interval from the date of diagnosis to the Medicare date of death	3 years

Collaborators and Investigators

• Sponsor: Zhengzhou University
• Collaborators: The First Affiliated Hospital of Zhengzhou University; Luoyang Central Hospital; Xinyang Central Hospital; Third Affiliated Hospital of Zhengzhou University; People's Hospital of Zhengzhou University; Anyang Regional Hospital; Zhoukou Central Hospital; the cancer hospital of Zhengzhou University; Center hospital of Nanyang; Center hospital of Shangqiu; Center hospital of Zhumadian; First People's Hospital of Kaifeng
• Investigators: Principal Investigator: Liu Bingqian, Ph.D MD, The First Affiliated Hospital of Zhengzhou University

Study record dates

Study Major Dates

• Study Start: January 1, 2003
• Primary Completion (Actual): December 1, 2011
• Study Completion (Actual): December 1, 2011

Study Registration Dates

• First Submitted: June 2, 2012
• First Submitted That Met QC Criteria: June 5, 2012
• First Posted (Estimate): June 8, 2012

Study Record Updates

• Last Update Posted (Estimate): June 8, 2012
• Last Update Submitted That Met QC Criteria: June 5, 2012
• Last Verified: June 1, 2012

More Information

Terms related to this study

• Keywords: Prostate Cancer; Rural; Prostatic Neoplasms; Disease Management; Urban
• Additional Relevant MeSH Terms: Neoplasms; Urogenital Neoplasms; Neoplasms by Site; Genital Neoplasms, Male; Prostatic Diseases; Prostatic Neoplasms
• Other Study ID Numbers: ZZU2012