- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02058498
Increasing Activity in Liver Transplant Patients
April 28, 2016 updated by: Jennifer L. Serotta, A.R.N.P., Mayo Clinic
Increasing Physical Activity in Post Liver Transplant Patients
Will adult liver transplant patients who are provided with physical activity (walking) instructions increase their physical activity and perceive an improved quality of life?
Study Overview
Study Type
Interventional
Enrollment (Actual)
12
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Florida
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Jacksonville, Florida, United States, 32224
- Mayo Clinic in Florida
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 65 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion criteria:
- Adult patients 18-65 years of age who receive a liver transplant at Mayo Clinic Jacksonville.
- Adult patients who are 5-21 days post liver transplant.
- Must be followed by Mayo Clinic Jacksonville at 4 months postoperatively.
- Approved by a hepatologist and/or transplant surgeon to participate.
Exclusion criteria:
- Patients with active infections
- Patients with encephalopathy or cognitive dysfunction
- Patients who receive a combined liver-kidney transplant
- Patients with severe debility
- Patients who require assistance to ambulate.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Liver Transplant Patients
Participants will be provided physical activity walking instructions and asked to record their daily activity on an activity log.
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Participants will be provided physical activity walking instructions and asked to record their daily activity on an activity log.
Participants will be given the International Physical Activity Questionnaire and asked about their quality of life at baseline, at 6 weeks and at 4 months.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Physical Activity Measured by the International Physical Activity Questionnaire (IPAQ)
Time Frame: Baseline, 6 weeks
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The IPAQ calculates the metabolic equivalent (MET) score by asking participants the days and minutes exercised in three categories of intensity (vigorous, moderate, and walking) during the previous one week.
The following formula is used to calculate the MET: MET=8(vigorous activity) (minutes) + 4 (moderate activity)(minutes) +3.3 (walking activity) (minutes).
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Baseline, 6 weeks
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Quality of Life at Baseline, 6 Weeks, and 4 Months
Time Frame: Baseline, 6 weeks, 4 months
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Participants reported their perceived quality of life using a scale 1 - 10, with 1 being the worst and 10 being the best.
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Baseline, 6 weeks, 4 months
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Number of Patients Who Document Their Physical Activity
Time Frame: Baseline to 6 weeks, repeated measure at 4 months
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8 participants documented their physical activity at 6 weeks.
6 participants documented their physical activity at 4 months.
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Baseline to 6 weeks, repeated measure at 4 months
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Jennifer Serotta, ARNP, Mayo Clinic
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
February 1, 2014
Primary Completion (Actual)
December 1, 2014
Study Completion (Actual)
December 1, 2014
Study Registration Dates
First Submitted
February 4, 2014
First Submitted That Met QC Criteria
February 6, 2014
First Posted (Estimate)
February 10, 2014
Study Record Updates
Last Update Posted (Estimate)
June 6, 2016
Last Update Submitted That Met QC Criteria
April 28, 2016
Last Verified
April 1, 2016
More Information
Terms related to this study
Other Study ID Numbers
- 13-004699
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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