Effect of Compression Garments on Exercise Performance Following Acute High Intensity Exercise

To examine the influence of compression garments manufactured with Far-Infrared technology on exercise performance during and after repeated eccentric isokinetic muscle actions of the leg extensors.

Study Overview

• Status: Completed
• Conditions: Muscle Damage
• Intervention / Treatment: Other: Far Infrared Fabric; Other: Spandex

Detailed Description

Participants: Eighty recreationally active (1-5 hrs per week) healthy participants between the ages of 18 - 35 will visit the Neuromuscular Research Laboratory on 6 separate occasions, with 4 of those occasions also requiring a visit to Health services for a blood draw.

Procedures (methods): During pre-screening, each participant will complete an informed consent document, a health history questionnaire, and have their stature and body mass assessed. A familiarization session will then be conducted on a separate day where all participants will practice the strength assessment, eccentric isokinetic protocol, and ultrasound assessments. Participants will be assigned to 1 of the 4 treatment groups based on their initial maximal isometric strength values using a matched-participants design. The first experimental session will then begin 2-10 days later, where the participants will perform the repeated eccentric exercise protocol (10 sets of 15 eccentric contractions 210 deg/sec with 3 min of rest between sets) with the non-dominant leg following a 60 min rest period where they will wear the apparel and perform a 5 min warm-up on a cycle ergometer. Follow-up blood draws and strength and ultrasound assessments will be obtained at 24 and 48 hours post-exercise. Each participant will also complete a visual analog scale at baseline, 24, 48, and 72 hours post-exercise to examine perceived muscle soreness.

• Study Type: Interventional
• Enrollment (Actual): 84
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • North Carolina
    • Chapel Hill, North Carolina, United States, 27599
      • Exercise and Sport Science (University of North Carolina)

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 35 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Cohort of Adult Males & Females
• Participant is between the ages of 18-35
• Healthy, Recreationally Active (1-5 hours per week)
• Participant has provided written and dated informed consent to participate in the study
• Participant is apparently healthy and free from disease, as determined by a health history questionnaire
• Participant agrees to abstain from smoking, caffeine (4hrs prior), tobacco (24hrs prior), and alcohol (24 hrs) before testing days
• Participant agrees to abstain from exercise 24 hours prior to each testing visit and after 72 hours of the induced exercise damage
• Participant will refrain from the use of non-steroidal anti-inflammatory drugs (NSAIDs) and protein supplementation 24 hours before the exercise testing protocol, as well as for the 72 hour period following the exercise testing protocol.

Exclusion Criteria:

• Participant is using, or has used one of the following dietary supplements within 12 weeks prior to enrollment: beta-alanine, creatine, taurine, or any supplemental antioxidants (Acai, pomegranate, beet juice).
• Participant is in, or has participated in another clinical trial within 6 weeks prior to enrollment
• Participant has a known allergy or sensitivity to test product (determined from health history questionnaire and consent form)

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Factorial Assignment
• Masking: Triple

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Compression + normal garment; Far Infrared Fabric during exercise + Spandex at night	Other: Far Infrared Fabric; Other: Spandex
Active Comparator: Normal Garment + Test garment at night; Spandex during exercise + Far Infrared Fabric at night	Other: Far Infrared Fabric; Other: Spandex
Sham Comparator: Normal Garment + normal garment; Spandex during exercise + Spandex at night	Other: Spandex
Active Comparator: Test garment + Test garment; Far Infrared Fabric during exercise + Far Infrared Fabric at night	Other: Far Infrared Fabric

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Maximal Voluntary Contraction (MVC)	up to 72 hours

Secondary Outcome Measures

Outcome Measure	Time Frame
Creatine Kinase	baseline, 24 hrs and 48 hrs post

Collaborators and Investigators

• Sponsor: University of North Carolina, Chapel Hill
• Collaborators: Rhodia, Inc

Publications and helpful links

Helpful Links

• Related Info

Study record dates

Study Major Dates

• Study Start: February 1, 2014
• Primary Completion (Actual): August 1, 2014
• Study Completion (Actual): August 1, 2014

Study Registration Dates

• First Submitted: February 24, 2014
• First Submitted That Met QC Criteria: February 27, 2014
• First Posted (Estimate): March 3, 2014

Study Record Updates

• Last Update Posted (Actual): July 11, 2017
• Last Update Submitted That Met QC Criteria: April 13, 2017
• Last Verified: April 1, 2017

More Information

Terms related to this study

• Keywords: compression, isokinetic, far-infrared
• Other Study ID Numbers: 13-3101

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No