- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02281747
Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries
Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries and Other Databases
Background:
- Orthopedic procedures are common in the United States. These include joint replacement and spine surgeries. Researchers want to study data about these procedures over time. They want to see if treatment has gotten better. They also want to find ways to change the care that people get before and after they have these procedures. These changes may lower the risk of problems people can have during and after treatment. They may also improve people s results.
Objectives:
- To study a series of questions about surgery, medicine, treatments, and outcomes for orthopedic procedures.
Eligibility:
- Data from the U.S. Centers for Medicare and Medicaid Services from 1999 to 2015.
Design:
- Researchers will look at data for people ages 20-100.
- No new participants will be used in this study.
- The study will last 6 years.
Study Overview
Status
Conditions
Detailed Description
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
Maryland
-
Bethesda, Maryland, United States, 20892
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), 9
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
- Subjects will be either Medicare or Medicaid beneficiaries with available claims from 1999 to 2015. For projects requiring detailed medication information, inclusion will be limited to those with Part D claims from 2006 to 2015. Eligibility for each project will be based on claims for the appropriate disease (e.g. RA) or procedure (e.g. hip arthroplasty).
Medicare beneficiaries will be excluded (or censored) if they do not have both Part A and Part B coverage, or enrolled in Medicare Advantage plans (Part C), as detailed claims for these beneficiaries are not available. We will also exclude dual-eligible (Medicare and Medicaid recipients) as these subjects have distinct clinical conditions (e.g. blindness) that distinguishes them from most Medicare beneficiaries. There will be no exclusions based on gender, race, ethnicity, or cognitive impairment.
Study Plan
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Retrospective
Cohorts and Interventions
Group / Cohort |
---|
affected with arthritis
arthritis may be either rheumatoid, osteoarthritis, or ankylosing spondylitis
|
unaffected with arthritis
in some analyses, the comparison is by arthritis status. in other analyses, it is within arthritis status by clinically relevant subgroups.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Complications
Time Frame: 30 days
|
Complications
|
30 days
|
Collaborators and Investigators
Investigators
- Principal Investigator: Robert A Colbert, M.D., National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimated)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Infections
- Immune System Diseases
- Autoimmune Diseases
- Joint Diseases
- Musculoskeletal Diseases
- Rheumatic Diseases
- Connective Tissue Diseases
- Spinal Diseases
- Bone Diseases
- Spondylarthropathies
- Spondylarthritis
- Bone Diseases, Infectious
- Ankylosis
- Axial Spondyloarthritis
- Arthritis
- Arthritis, Rheumatoid
- Spondylitis
- Spondylitis, Ankylosing
Other Study ID Numbers
- 999915010
- 15-AR-N010
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
IPD Plan Description
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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