Transpulmonary Pressures in Mechanical Ventilated Patients With Morbid Obesity

December 6, 2024 updated by: Rosa Estrada Y Martin, The University of Texas Health Science Center, Houston

The study consists in determine the transpulmonary pressure in morbidly obesity patients that require mechanical ventilation.

  • both gender
  • only adults
  • Medical intensive care patients.

Study Overview

Status

Completed

Conditions

Detailed Description

We are studying adult patients with morbid obesity with respiratory failure requiring mechanical ventilation.

We are measuring transesophageal presssures to estimate ideal PEEP and evaluate hemodynamic parameters.

Study Type

Observational

Enrollment (Actual)

15

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Texas
      • Houston, Texas, United States, 77030
        • The University of Texas - HSC at Houston

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adults mechanically ventilated with morbid obesity

Description

Inclusion Criteria:

  • both gender
  • morbid obesity
  • hemodynamically stable

Exclusion Criteria:

  • pregnant patients
  • cirrhotic patients with esophageal varicose

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
transpulmonary pressures
Esophageal balloon to measure transpulmonary pressures. PEEP adjustment as per transpulmonary pressures.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Transpulmonary pressure
Time Frame: one year
We will record the changes in transpulmonary pressure after adjusting PEEP (measure in cmH2O).
one year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
hemodynamics
Time Frame: one year
we will review hemodynamic changes while adjusting PEEP (BP, HR).
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

The University of Texas Health Science Center, Houston

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2018

Primary Completion (Actual)

December 1, 2024

Study Completion (Actual)

December 1, 2024

Study Registration Dates

First Submitted

September 16, 2014

First Submitted That Met QC Criteria

December 2, 2014

First Posted (Estimated)

December 5, 2014

Study Record Updates

Last Update Posted (Actual)

December 12, 2024

Last Update Submitted That Met QC Criteria

December 6, 2024

Last Verified

December 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HSC-MS-14-0444

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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