- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02346981
Resistance Training and Post-exercise Blood Pressure in Normotensive Older Women
Chronic Resistance Training and Post-exercise Blood Pressure in Normotensive Older Women
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Older (≥60 years) normotensive and physically inactive women were recruited. Women were randomized into training group (TG) or control group (CG) and submitted to 12 weeks of intervention. The intervention programs were divided into three phases: initial (first two weeks), intermediate (from week 3 to week 10) and final (last two weeks). The TG was submitted to a resistance training program that consisted of eight exercises performed in two sets of 10 to 15 repetitions, three times per week. The CG performed a stretching training program for the major muscle groups, in sessions of 30 minutes, twice a week. These interventions were maintained during the 12 weeks.
During initial and final phases subjects of both groups were submitted to two acute experimental sessions: resistance exercise and control, which were performed in random order. The resistance exercise session was similar to those performed during the resistance training program (i.e., 7 exercises, 2 sets, 10-15 repetitions). In the control session participants remained seated for 40 min. Before and after each session the BP parameters were obtained. The chronic effect of resistance training on post-exercise BP were assessed by analyzing the changes (∆) in BP after acute experimental sessions at initial and final phases. The correlation between acute and chronic responses of blood pressure following resistance training was analyses correlating the acute blood pressure observed in initial phase with the chronic effect of resistance training on rest blood pressure.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- normotensive female;
- aged 60-to-80 years old;
- nonsmokers;
- without diabetes, cardiac disease or renal dysfunction;
- not practicing regular physical activity over the six months preceding the beginning of the investigation;
- being free of any musculoskeletal or other disorders that might affect their ability to participate in the study,
- should not be taking drugs with inotropic or chronotropic actions;
- should not be using hormonal replacement therapy;
- have no restriction for participation in physical exercise, after diagnostic, graded exercise stress test with 12-lead ECG.
Exclusion Criteria:
- insufficient attendance to the training sessions (< 85 % of the total sessions);
- unavailability of time to perform the evaluations
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Intervention gruop
The intervention group was submitted to a resistance training program that consisted of eight exercises performed in two sets of 10 to 15 repetitions, three times per week.
|
Supervised resistance training program was performed on three nonconsecutive days per week at morning period for 12 weeks.
The resistance training program included eight exercises in two consecutive sets of 10-15 repetitions until moderate fatigue, except for crunch exercise which was performed on 20 to 30 repetitions without overload.
The participants were instructed to perform repetitions at a ratio of 1:2 (concentric and eccentric phases, respectively).
Subjects rested for 60- to 90-s between each set and for 2- to 3-min between each exercise.
Each subject was individually supervised.
Increases of 2-5 % for the upper limb exercises and 5-10 % for the lower limb exercises every time that subjects were able to complete 15 repetitions in both sets.
|
No Intervention: Control group
The control group performed a stretching training program for the major muscle groups, in sessions of 30 minutes, twice a week
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
changes in clinic blood pressure
Time Frame: baseline, 12 weeks
|
baseline, 12 weeks
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
changes in post-exercise blood pressure
Time Frame: baseline, 12 weeks
|
baseline, 12 weeks
|
Collaborators and Investigators
Investigators
- Principal Investigator: Aline M Gerage, Master, Universidade Estadual de Londrina
- Study Director: Edilson S Cyrino, Doctor, Universidade Estadual de Londrina
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- PIUEL2008
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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