Metabolic Changes as a Diagnostic Indicator for Cancer

February 9, 2015 updated by: Prof. dr. Michiel Thomeer, Hasselt University
This study aims to determine whether metabolic changes occur in blood plasma of cancer patients, and whether these changes can be used as a biomarker to detect cancer. These analyses will be done by means of nuclear magnetic resonance (NMR) spectroscopy.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

426

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Belgium
    • Limburg
      • Genk, Limburg, Belgium, 3600
        • Ziekenhuis Oost-Limburg
      • Hasselt, Limburg, Belgium, 3500
        • Hasselt University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Diagnosis of breast or lung cancer

Description

Inclusion Criteria:

  • Diagnosis of breast or lung cancer (new lesion)

Exclusion Criteria:

  • Not fasted for at least 6 hours
  • Plasma glucose concentration ≥ 200 mg/dl
  • Intake of medication at the day of investigation
  • History/treatment of cancer in the previous 5 years

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
control subjects
Other: Venous blood sample
Collection of a venous blood sample to investigate metabolic changes in blood
lung cancer patients
Other: Venous blood sample
Collection of a venous blood sample to investigate metabolic changes in blood
breast cancer patients
Other: Venous blood sample
Collection of a venous blood sample to investigate metabolic changes in blood

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Metabolic phenotype of cancer
Time Frame: day 1
Significant metabolic changes in blood between cancer patients & control subjects
day 1

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hasselt University

Collaborators

Ziekenhuis Oost-Limburg
Algemeen Ziekenhuis Vesalius
Ziekenhuis Maas en Kempen
Mariaziekenhuis Noord-Limburg

Investigators

  • Principal Investigator: Michiel Thomeer, prof. dr., Ziekenhuis Oost-Limburg
  • Principal Investigator: Kurt Baeten, dr., Hasselt University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2009

Primary Completion (Actual)

July 1, 2012

Study Completion (Actual)

July 1, 2012

Study Registration Dates

First Submitted

December 10, 2013

First Submitted That Met QC Criteria

February 9, 2015

First Posted (Estimate)

February 13, 2015

Study Record Updates

Last Update Posted (Estimate)

February 13, 2015

Last Update Submitted That Met QC Criteria

February 9, 2015

Last Verified

February 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 09/046U

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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