The Follow Study of Speech Functions in Preschool Children With Cerebral Palsy: Clinical Measures and Acoustic Analysis

The aims of this study:

1. to investigate the difference in motor speech functions among children with cerebral palsy (CP) of different motor severities.
2. to investigate the longitudinal in motor speech functions at 6 months follow-up phase among children with CP of different motor severities.
3. the correlation between motor severity, personal factors, family factors, language ability and motor speech in children with CP.
4. to identify the variables that can predict motor speech functions in children with CP.

Study Overview

• Status: Completed
• Conditions: Cerebral Palsy

Detailed Description

Mental impairment, language and speech disorders are the common associated problems in children with CP. Previous studies focus on language and motor speech dysfunctions in children with CP at school-age child, adolescents and adults. Few literatures identify the determinants for predicted the motor speech performance in these children. It is important issue to follow-up the language and motor speech functions in children with CP. These data will provide clinicians for outcome prediction and goal setting.The aims of this study: (1) to investigate the difference in motor speech functions among children with CP of different motor severities, and(2) to investigate the longitudinal in motor speech functions at 6 months follow-up phase among children with CP of different motor severities, and(3) the correlation between motor severity, personal factors, family factors, language ability and motor speech in children with CP, and(4) to identify the variables that can predict motor speech functions in children with CP.

• Study Type: Observational
• Enrollment (Actual): 46

Contacts and Locations

Study Locations

• Taiwan
  • Taoyuan, Taiwan, 333
    • Chang Gung Memorial Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 4 years to 8 years (Child)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

children with CP having language ability greater than 3 years

Description

Inclusion Criteria:

1. Subjects between the ages of 4-8 years old children.
2. Subjects which aged 7 years or older should sign a consent form by themself.
3. In line with the assessment, the case must be able to follow simple verbal commands, and can be done in a simple sentence description.
4. were diagnosed with spastic cerebral palsy.

Exclusion Criteria:

1. physiological condition is unstable: Included in three months for surgery or infection and other major diseases
2. there is progressive or degenerative symptoms or diseases (such as degenerative epilepsy), peripheral nerve injury, spinal cord injury.
3. visual perception or hearing problems, after correction difficult communicators.
4. other movement disorders patterns for children with cerebral palsy (athetoid type, offset type, etc.).

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort
Typical developmental children; Normal children
CP children with GMFCS level I and II; Children with CP were classified into Levels I-II based on the Gross Motor Function Classification System (GMFCS).
CP children with GMFCS level III and IV; Children with CP were classified into Levels III-IV based on the Gross Motor Function Classification System (GMFCS).

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change of Peabody Picture Vocabulary Test-Revised	Children with CP underwent the assessments of Peabody Picture Vocabulary Test-Revised.	baseline and six months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change of Percentage of Correct Consonant in six months	Children with CP underwent the assessments of Percentage of Correct Consonant	baseline and six months

Collaborators and Investigators

• Sponsor: Chang Gung Memorial Hospital
• Investigators: Principal Investigator: Chia-Ling Chen, PhD, Department of Physical Medicine & Rehabilitation, Chang Gung Memorial Hospital

Study record dates

Study Major Dates

• Study Start: October 1, 2010
• Primary Completion (Actual): July 1, 2012
• Study Completion (Actual): August 1, 2012

Study Registration Dates

• First Submitted: February 25, 2015
• First Submitted That Met QC Criteria: March 2, 2015
• First Posted (Estimate): March 4, 2015

Study Record Updates

• Last Update Posted (Estimate): March 11, 2015
• Last Update Submitted That Met QC Criteria: March 10, 2015
• Last Verified: August 1, 2010

More Information

Terms related to this study

• Keywords: follow-up; language; cerebral palsy; acoustic; motor speech
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Brain Damage, Chronic; Cerebral Palsy; Paralysis
• Other Study ID Numbers: 99-1917B