Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients

June 24, 2015 updated by: yin ying zhao, Wenzhou Medical University

The purpose of this study is to identify age-related changes in chinese meibomian glands that may be associated with meibomian gland dysfunction (MGD).

Study Overview

Status

Unknown

Conditions

Dry Eye

Study Type

Observational

Enrollment (Anticipated)

100

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

China
- Zhejiang
  - Wenzhou, Zhejiang, China, 325027
    - Recruiting
    - Wenzhou Medical University
    - Contact:
      
      XIXIA DING, PHD
      
      Phone Number: 86-057788068859

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

40 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

This study was consisted of patients with older than 40 years of age who complained with dry eye. The institutional review board of Wenzhou Medical College approved the study protocol, and all patients provided their informed consent.

Description

Inclusion Criteria:

have dry eye symptom
have meibomian gland dysfunction

Exclusion Criteria:

diabetes
history of ocular surgery
systemic disease or inflammation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort
group1 This study was consisted of patients with older than 40 years of age who complained with dry eye.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Tear film break-up time Time Frame: 1 year	Tear film break-up time (TBUT) was evaluated by placing a single fluorescein strip over the inferior tear meniscus after instilling a drop of normal saline.	1 year
Lower tear meniscus Time Frame: 1 year	Lower tear meniscus was evaluated by keratography	1 year
The morphology of meibomian glands Time Frame: 1 year	The morphology of meibomian glands was evaluated by keratography	1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Wenzhou Medical University

Investigators

Study Chair: ZHAO YUNE, MS, Wenzhou Medical University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2015

Primary Completion (Anticipated)

April 1, 2016

Study Completion (Anticipated)

January 1, 2018

Study Registration Dates

First Submitted

June 15, 2015

First Submitted That Met QC Criteria

June 24, 2015

First Posted (Estimate)

June 25, 2015

Study Record Updates

Last Update Posted (Estimate)