Infraclavicular Perineural Dexmedetomidine

February 26, 2017 updated by: ILKE KUPELI, Cukurova University

Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Improve Postoperative Analgesia Deadline?

Infraclavicular block is one of the peripheral nerve block used in upper extremity surgery. Adjuvant agents are used in peripheral nerve blocks to increase the duration and block quality. We investigated that the effects of patient-controlled perineural dexmedetomidine application on postoperative analgesia.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

60

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
    • Merkez
      • Erzincan, Merkez, Turkey, 24100
        • Erzincan University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • be undergoing distal upper extremity surgery
  • Be between 18-65 years
  • to agree to participate in research

Exclusion Criteria:

  • allergy to dexmedetomidine
  • AV block or bradycardia
  • being serious cardiac - liver - kidney function disorders
  • Being coagulopathy
  • neuropathy in the upper extremity
  • adrenoceptor agonists or antagonists use

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: perineural bupivacaine

patient-controlled infraclavicular perineural bupivacaine

(1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
Drug: Bupivacaine
patient- controlled infraclavicular perineural marcaine infusion
Drug: Dexmedetomidine
patient- controlled infraclavicular perineural marcaine with dexmedetomidine infusion
Experimental: perineural dexmedetomidine

patient-controlled infraclavicular perineural dexmedetomidine

(1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
Drug: Bupivacaine
patient- controlled infraclavicular perineural marcaine infusion
Drug: Dexmedetomidine
patient- controlled infraclavicular perineural marcaine with dexmedetomidine infusion

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
visual analog scale
Time Frame: 3 month
Scores range from 0 [no pain] to 10 [worst possible pain
3 month

Secondary Outcome Measures

Outcome Measure
Time Frame
side effects
Time Frame: 3 month
3 month
The effect of dexmedetomidine to the Ramsey Sedation Scale
Time Frame: 3 month
3 month

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cukurova University

Collaborators

Erzincan University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 1, 2015

Primary Completion (Actual)

December 1, 2015

Study Completion (Actual)

December 1, 2015

Study Registration Dates

First Submitted

September 14, 2015

First Submitted That Met QC Criteria

September 14, 2015

First Posted (Estimate)

September 16, 2015

Study Record Updates

Last Update Posted (Actual)

February 28, 2017

Last Update Submitted That Met QC Criteria

February 26, 2017

Last Verified

February 1, 2017

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Mengücek gazi

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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