Emotional Brain Processes in Recreational Cannabis Users

February 1, 2017 updated by: Benjamin Becker, University of Electronic Science and Technology of China

Effects of Recreational Cannabis Use on Brain Activation Patterns Associated With Emotional Processes

This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Anticipated)

50

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 40 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Sampling Method

Non-Probability Sample

Study Population

Recreational male cannabis users

Description

Inclusion Criteria:

  • Recreational cannabis use
  • 72 hours of abstinence

Exclusion Criteria:

  • neurological disorders
  • psychiatric disorders according to DSM-4

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Recreational Cannabis Use
ages 18-40
Other: fMRI
Healthy control subjects
socio-demographically matched
Other: fMRI

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
fMRI neural correlates of emotional brain processes in recreational cannabis users after 72 hours of abstinence
Time Frame: one time point = fMRI assessment after 72 hours of abstinence
Activation patterns in brain regions known to be involved in emotional processing and to be altered by cannabis use (e.g. striatum, prefrontal cortex, insula, ACC)
one time point = fMRI assessment after 72 hours of abstinence

Secondary Outcome Measures

Outcome Measure
Time Frame
Ratings of subjective experience (affect, craving)
Time Frame: one time point = during fMRI assessment after 72 hours of abstinence
one time point = during fMRI assessment after 72 hours of abstinence

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Electronic Science and Technology of China

Collaborators

German Research Foundation
University Hospital, Bonn

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2015

Primary Completion (ACTUAL)

December 1, 2015

Study Completion (ACTUAL)

December 1, 2016

Study Registration Dates

First Submitted

June 11, 2016

First Submitted That Met QC Criteria

June 11, 2016

First Posted (ESTIMATE)

June 15, 2016

Study Record Updates

Last Update Posted (ESTIMATE)

February 2, 2017

Last Update Submitted That Met QC Criteria

February 1, 2017

Last Verified

February 1, 2017

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ART_Can_02

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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